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Results: 1 to 20 of 65

1.

Resetting the transcription factor network reverses terminal chronic hepatic failure.

Nishikawa T, Bell A, Brooks JM, Setoyama K, Melis M, Han B, Fukumitsu K, Handa K, Tian J, Kaestner KH, Vodovotz Y, Locker J, Soto-Gutierrez A, Fox IJ.

J Clin Invest. 2015 Apr 1;125(4):1533-44. doi: 10.1172/JCI73137. Epub 2015 Mar 16.

PMID:
25774505
2.

Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.

Tafaleng EN, Chakraborty S, Han B, Hale P, Wu W, Soto-Gutierrez A, Feghali-Bostwick CA, Wilson AA, Kotton DN, Nagaya M, Strom SC, Roy-Chowdhury J, Stolz DB, Perlmutter DH, Fox IJ.

Hepatology. 2015 Feb 18. doi: 10.1002/hep.27753. [Epub ahead of print]

PMID:
25690322
3.

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.

Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR.

Gastroenterology. 2015 Feb;148(2):392-402.e13. doi: 10.1053/j.gastro.2014.10.040. Epub 2014 Nov 4.

PMID:
25447848
4.

A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression.

Dutta-Moscato J, Solovyev A, Mi Q, Nishikawa T, Soto-Gutierrez A, Fox IJ, Vodovotz Y.

Front Bioeng Biotechnol. 2014 May 30;2:18. doi: 10.3389/fbioe.2014.00018. eCollection 2014.

5.

Reply to: "Is the pathway of energy metabolism modified in advanced cirrhosis?".

Nagrath D, Soto-Gutierrez A.

J Hepatol. 2014 Aug;61(2):453. doi: 10.1016/j.jhep.2014.04.040. Epub 2014 May 2. No abstract available.

6.

A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.

Nishikawa T, Bellance N, Damm A, Bing H, Zhu Z, Handa K, Yovchev MI, Sehgal V, Moss TJ, Oertel M, Ram PT, Pipinos II, Soto-Gutierrez A, Fox IJ, Nagrath D.

J Hepatol. 2014 Jun;60(6):1203-11. doi: 10.1016/j.jhep.2014.02.014. Epub 2014 Feb 26.

PMID:
24583248
7.

Assembly of human organs from stem cells to study liver disease.

Handa K, Matsubara K, Fukumitsu K, Guzman-Lepe J, Watson A, Soto-Gutierrez A.

Am J Pathol. 2014 Feb;184(2):348-57. doi: 10.1016/j.ajpath.2013.11.003. Epub 2013 Dec 12. Review.

8.

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury.

Yannam GR, Han B, Setoyama K, Yamamoto T, Ito R, Brooks JM, Guzman-Lepe J, Galambos C, Fong JV, Deutsch M, Quader MA, Yamanouchi K, Kabarriti R, Mehta K, Soto-Gutierrez A, Roy-Chowdhury J, Locker J, Abe M, Enke CA, Baranowska-Kortylewicz J, Solberg TD, Guha C, Fox IJ.

Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):404-11. doi: 10.1016/j.ijrobp.2013.10.037. Epub 2013 Dec 5.

9.

Transplantable liver organoids made from only three ingredients.

Willenbring H, Soto-Gutierrez A.

Cell Stem Cell. 2013 Aug 1;13(2):139-40. doi: 10.1016/j.stem.2013.07.014.

10.

The regeneration of organogenesis.

Soto-Gutierrez A, Wertheim JA.

Organogenesis. 2013 Jan-Mar;9(1):1-2. doi: 10.4161/org.24545. Epub 2013 Jan 1.

11.

Liver repopulation and regeneration: new approaches to old questions.

Duncan AW, Soto-Gutierrez A.

Curr Opin Organ Transplant. 2013 Apr;18(2):197-202. doi: 10.1097/MOT.0b013e32835f07e2. Review.

12.

Increased reprogramming of human fetal hepatocytes compared with adult hepatocytes in feeder-free conditions.

Hansel MC, Gramignoli R, Blake W, Davila J, Skvorak K, Dorko K, Tahan V, Lee BR, Tafaleng E, Guzman-Lepe J, Soto-Gutierrez A, Fox IJ, Strom SC.

Cell Transplant. 2014 Jan;23(1):27-38. doi: 10.3727/096368912X662453. Epub 2013 Feb 4.

13.

Analysis of alternative signaling pathways of endoderm induction of human embryonic stem cells identifies context specific differences.

Mathew S, Jaramillo M, Zhang X, Zhang LA, Soto-Gutiérrez A, Banerjee I.

BMC Syst Biol. 2012 Dec 15;6:154. doi: 10.1186/1752-0509-6-154.

14.

Whole-organ re-engineering: a regenerative medicine approach to digestive organ replacement.

Yagi H, Soto-Gutierrez A, Kitagawa Y.

Surg Today. 2013 Jun;43(6):587-94. doi: 10.1007/s00595-012-0396-1. Epub 2012 Nov 27. Review.

15.

Perspectives on whole-organ assembly: moving toward transplantation on demand.

Soto-Gutierrez A, Wertheim JA, Ott HC, Gilbert TW.

J Clin Invest. 2012 Nov;122(11):3817-23. doi: 10.1172/JCI61974. Epub 2012 Nov 1. Review.

16.

Human-scale whole-organ bioengineering for liver transplantation: a regenerative medicine approach.

Yagi H, Fukumitsu K, Fukuda K, Kitago M, Shinoda M, Obara H, Itano O, Kawachi S, Tanabe M, Coudriet GM, Piganelli JD, Gilbert TW, Soto-Gutierrez A, Kitagawa Y.

Cell Transplant. 2013;22(2):231-42. doi: 10.3727/096368912X654939. Epub 2012 Aug 27.

17.

Cellular therapy and bioartificial approaches to liver replacement.

Wertheim JA, Baptista PM, Soto-Gutierrez A.

Curr Opin Organ Transplant. 2012 Jun;17(3):235-40. doi: 10.1097/MOT.0b013e3283534ec9. Review.

18.

The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis.

Liu L, Yannam GR, Nishikawa T, Yamamoto T, Basma H, Ito R, Nagaya M, Dutta-Moscato J, Stolz DB, Duan F, Kaestner KH, Vodovotz Y, Soto-Gutierrez A, Fox IJ.

Hepatology. 2012 May;55(5):1529-39. doi: 10.1002/hep.24815. Epub 2012 Apr 4.

19.

Excorporeal normothermic machine perfusion resuscitates pig DCD livers with extended warm ischemia.

Xu H, Berendsen T, Kim K, Soto-Gutiérrez A, Bertheium F, Yarmush ML, Hertl M.

J Surg Res. 2012 Apr;173(2):e83-8. doi: 10.1016/j.jss.2011.09.057. Epub 2011 Oct 24.

20.

Bioengineering in organ transplantation: targeting the liver.

Fukumitsu K, Yagi H, Soto-Gutierrez A.

Transplant Proc. 2011 Jul-Aug;43(6):2137-8. doi: 10.1016/j.transproceed.2011.05.014. Review.

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