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Results: 1 to 20 of 31


Impact of β-lactamase inhibition on the activity of ceftaroline against Mycobacterium tuberculosis and Mycobacterium abscessus.

Dubée V, Soroka D, Cortes M, Lefebvre AL, Gutmann L, Hugonnet JE, Arthur M, Mainardi JL.

Antimicrob Agents Chemother. 2015 Mar 2. pii: AAC.05080-14. [Epub ahead of print]


Oxyphytosterols as active ingredients in wheat bran suppress human colon cancer cell growth: identification, chemical synthesis, and biological evaluation.

Zhu Y, Soroka D, Sang S.

J Agric Food Chem. 2015 Mar 4;63(8):2264-76. doi: 10.1021/jf506361r. Epub 2015 Feb 18.


Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo.

Chen H, Fu J, Chen H, Hu Y, Soroka DN, Prigge JR, Schmidt EE, Yan F, Major MB, Chen X, Sang S.

Chem Res Toxicol. 2014 Sep 15;27(9):1575-85. doi: 10.1021/tx500211x. Epub 2014 Sep 2.


Cysteine-conjugated metabolites of ginger components, shogaols, induce apoptosis through oxidative stress-mediated p53 pathway in human colon cancer cells.

Fu J, Chen H, Soroka DN, Warin RF, Sang S.

J Agric Food Chem. 2014 May 21;62(20):4632-42. doi: 10.1021/jf501351r. Epub 2014 May 12.


A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells.

Ly T, Ahmad Y, Shlien A, Soroka D, Mills A, Emanuele MJ, Stratton MR, Lamond AI.

Elife. 2014 Jan 1;3:e01630. doi: 10.7554/eLife.01630.


Studies of inactivation mechanism of non-enveloped icosahedral virus by a visible ultrashort pulsed laser.

Tsen SW, Kingsley DH, Poweleit C, Achilefu S, Soroka DS, Wu TC, Tsen KT.

Virol J. 2014 Feb 5;11:20. doi: 10.1186/1743-422X-11-20.


Induction of lung cancer cell apoptosis through a p53 pathway by [6]-shogaol and its cysteine-conjugated metabolite M2.

Warin RF, Chen H, Soroka DN, Zhu Y, Sang S.

J Agric Food Chem. 2014 Feb 12;62(6):1352-62. doi: 10.1021/jf405573e. Epub 2014 Jan 30.


Characterization of broad-spectrum Mycobacterium abscessus class A β-lactamase.

Soroka D, Dubée V, Soulier-Escrihuela O, Cuinet G, Hugonnet JE, Gutmann L, Mainardi JL, Arthur M.

J Antimicrob Chemother. 2014 Mar;69(3):691-6. doi: 10.1093/jac/dkt410. Epub 2013 Oct 16.


[10]-Gingerdiols as the major metabolites of [10]-gingerol in zebrafish embryos and in humans and their hematopoietic effects in zebrafish embryos.

Chen H, Soroka DN, Haider J, Ferri-Lagneau KF, Leung T, Sang S.

J Agric Food Chem. 2013 Jun 5;61(22):5353-60. doi: 10.1021/jf401501s. Epub 2013 May 23.


Cysteine-conjugated metabolite of ginger component [6]-shogaol serves as a carrier of [6]-shogaol in cancer cells and in mice.

Chen H, Soroka DN, Zhu Y, Hu Y, Chen X, Sang S.

Chem Res Toxicol. 2013 Jun 17;26(6):976-85. doi: 10.1021/tx4001286. Epub 2013 May 15.


Metabolites of ginger component [6]-shogaol remain bioactive in cancer cells and have low toxicity in normal cells: chemical synthesis and biological evaluation.

Zhu Y, Warin RF, Soroka DN, Chen H, Sang S.

PLoS One. 2013;8(1):e54677. doi: 10.1371/journal.pone.0054677. Epub 2013 Jan 30.


Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human.

Chen H, Soroka D, Zhu Y, Sang S.

Mol Nutr Food Res. 2013 May;57(5):865-76. doi: 10.1002/mnfr.201200708. Epub 2013 Jan 16.


Characterization of thiol-conjugated metabolites of ginger components shogaols in mouse and human urine and modulation of the glutathione levels in cancer cells by [6]-shogaol.

Chen H, Soroka DN, Hu Y, Chen X, Sang S.

Mol Nutr Food Res. 2013 Mar;57(3):447-58. doi: 10.1002/mnfr.201200679. Epub 2013 Jan 16.


Structure elucidation and chemical profile of sphingolipids in wheat bran and their cytotoxic effects against human colon cancer cells.

Zhu Y, Soroka DN, Sang S.

J Agric Food Chem. 2013 Jan 30;61(4):866-74. doi: 10.1021/jf3047863. Epub 2013 Jan 16.


A new boson with a mass of 125 GeV observed with the CMS experiment at the Large Hadron Collider.

CMS Collaboration.

Science. 2012 Dec 21;338(6114):1569-75. doi: 10.1126/science.1230816. Erratum in: Science. 2013 Mar 15;339(6125):1275.


6-gingerdiols as the major metabolites of 6-gingerol in cancer cells and in mice and their cytotoxic effects on human cancer cells.

Lv L, Chen H, Soroka D, Chen X, Leung T, Sang S.

J Agric Food Chem. 2012 Nov 14;60(45):11372-7. doi: 10.1021/jf303879b. Epub 2012 Nov 6.


Predatory bacteria as natural modulators of Vibrio parahaemolyticus and Vibrio vulnificus in seawater and oysters.

Richards GP, Fay JP, Dickens KA, Parent MA, Soroka DS, Boyd EF.

Appl Environ Microbiol. 2012 Oct;78(20):7455-66. Epub 2012 Aug 17.


Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols.

Zhu Y, Soroka DN, Sang S.

J Agric Food Chem. 2012 Sep 5;60(35):8624-31. doi: 10.1021/jf302872a. Epub 2012 Aug 23.


Metabolism of [6]-shogaol in mice and in cancer cells.

Chen H, Lv L, Soroka D, Warin RF, Parks TA, Hu Y, Zhu Y, Chen X, Sang S.

Drug Metab Dispos. 2012 Apr;40(4):742-53. doi: 10.1124/dmd.111.043331. Epub 2012 Jan 13.


Synthesis and proteasome inhibition of lithocholic acid derivatives.

Dang Z, Lin A, Ho P, Soroka D, Lee KH, Huang L, Chen CH.

Bioorg Med Chem Lett. 2011 Apr 1;21(7):1926-8. doi: 10.1016/j.bmcl.2011.02.041. Epub 2011 Feb 17.

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