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Items: 1 to 20 of 32


Determining the origin of synchronous multifocal bladder cancer by exome sequencing.

Acar Ö, Özkurt E, Demir G, Saraç H, Alkan C, Esen T, Somel M, Lack NA.

BMC Cancer. 2015 Nov 9;15:871. doi: 10.1186/s12885-015-1859-8.


Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa.

Alkan C, Kavak P, Somel M, Gokcumen O, Ugurlu S, Saygi C, Dal E, Bugra K, Güngör T, Sahinalp SC, Özören N, Bekpen C.

BMC Genomics. 2014 Nov 7;15:963. doi: 10.1186/1471-2164-15-963.


Transcriptomic insights into human brain evolution: acceleration, neutrality, heterochrony.

Somel M, Rohlfs R, Liu X.

Curr Opin Genet Dev. 2014 Dec;29:110-9. doi: 10.1016/j.gde.2014.09.001. Epub 2014 Sep 16. Review.


Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA.

Huerta-Sánchez E, Jin X, Asan, Bianba Z, Peter BM, Vinckenbosch N, Liang Y, Yi X, He M, Somel M, Ni P, Wang B, Ou X, Huasang, Luosang J, Cuo ZX, Li K, Gao G, Yin Y, Wang W, Zhang X, Xu X, Yang H, Li Y, Wang J, Wang J, Nielsen R.

Nature. 2014 Aug 14;512(7513):194-7. doi: 10.1038/nature13408. Epub 2014 Jul 2.


Shared signatures of social stress and aging in peripheral blood mononuclear cell gene expression profiles.

Snyder-Mackler N, Somel M, Tung J.

Aging Cell. 2014 Oct;13(5):954-7. doi: 10.1111/acel.12239. Epub 2014 Jun 23.


Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears.

Liu S, Lorenzen ED, Fumagalli M, Li B, Harris K, Xiong Z, Zhou L, Korneliussen TS, Somel M, Babbitt C, Wray G, Li J, He W, Wang Z, Fu W, Xiang X, Morgan CC, Doherty A, O'Connell MJ, McInerney JO, Born EW, Dalén L, Dietz R, Orlando L, Sonne C, Zhang G, Nielsen R, Willerslev E, Wang J.

Cell. 2014 May 8;157(4):785-94. doi: 10.1016/j.cell.2014.03.054.


Classic selective sweeps revealed by massive sequencing in cattle.

Qanbari S, Pausch H, Jansen S, Somel M, Strom TM, Fries R, Nielsen R, Simianer H.

PLoS Genet. 2014 Feb 27;10(2):e1004148. doi: 10.1371/journal.pgen.1004148. eCollection 2014 Feb.


Evolution of human longevity uncoupled from caloric restriction mechanisms.

Zhao G, Guo S, Somel M, Khaitovich P.

PLoS One. 2014 Jan 6;9(1):e84117. doi: 10.1371/journal.pone.0084117. eCollection 2014.


A scan for human-specific relaxation of negative selection reveals unexpected polymorphism in proteasome genes.

Somel M, Wilson Sayres MA, Jordan G, Huerta-Sanchez E, Fumagalli M, Ferrer-Admetlla A, Nielsen R.

Mol Biol Evol. 2013 Aug;30(8):1808-15. doi: 10.1093/molbev/mst098. Epub 2013 May 22.


Early gene expression divergence between allopatric populations of the house mouse (Mus musculus domesticus).

Bryk J, Somel M, Lorenc A, Teschke M.

Ecol Evol. 2013 Mar;3(3):558-68. doi: 10.1002/ece3.447. Epub 2013 Jan 31.


Widespread splicing changes in human brain development and aging.

Mazin P, Xiong J, Liu X, Yan Z, Zhang X, Li M, He L, Somel M, Yuan Y, Phoebe Chen YP, Li N, Hu Y, Fu N, Ning Z, Zeng R, Yang H, Chen W, Gelfand M, Khaitovich P.

Mol Syst Biol. 2013;9:633. doi: 10.1038/msb.2012.67.


Human brain evolution: transcripts, metabolites and their regulators.

Somel M, Liu X, Khaitovich P.

Nat Rev Neurosci. 2013 Feb;14(2):112-27. doi: 10.1038/nrn3372. Epub 2013 Jan 17. Review.


A comparison of brain gene expression levels in domesticated and wild animals.

Albert FW, Somel M, Carneiro M, Aximu-Petri A, Halbwax M, Thalmann O, Blanco-Aguiar JA, Plyusnina IZ, Trut L, Villafuerte R, Ferrand N, Kaiser S, Jensen P, Pääbo S.

PLoS Genet. 2012 Sep;8(9):e1002962. doi: 10.1371/journal.pgen.1002962. Epub 2012 Sep 27.


Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content.

Weng K, Hu H, Xu AG, Khaitovich P, Somel M.

PLoS One. 2012;7(8):e43915. doi: 10.1371/journal.pone.0043915. Epub 2012 Aug 24.


Accelerated aging-related transcriptome changes in the female prefrontal cortex.

Yuan Y, Chen YP, Boyd-Kirkup J, Khaitovich P, Somel M.

Aging Cell. 2012 Oct;11(5):894-901. doi: 10.1111/j.1474-9726.2012.00859.x. Epub 2012 Aug 2.


Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques.

Liu X, Somel M, Tang L, Yan Z, Jiang X, Guo S, Yuan Y, He L, Oleksiak A, Zhang Y, Li N, Hu Y, Chen W, Qiu Z, Pääbo S, Khaitovich P.

Genome Res. 2012 Apr;22(4):611-22. doi: 10.1101/gr.127324.111. Epub 2012 Feb 2.


MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

Somel M, Liu X, Tang L, Yan Z, Hu H, Guo S, Jiang X, Zhang X, Xu G, Xie G, Li N, Hu Y, Chen W, Pääbo S, Khaitovich P.

PLoS Biol. 2011 Dec;9(12):e1001214. doi: 10.1371/journal.pbio.1001214. Epub 2011 Dec 6.


Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series.

Yuan Y, Chen YP, Ni S, Xu AG, Tang L, Vingron M, Somel M, Khaitovich P.

BMC Bioinformatics. 2011 Aug 18;12:347. doi: 10.1186/1471-2105-12-347.


Rapid metabolic evolution in human prefrontal cortex.

Fu X, Giavalisco P, Liu X, Catchpole G, Fu N, Ning ZB, Guo S, Yan Z, Somel M, Pääbo S, Zeng R, Willmitzer L, Khaitovich P.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6181-6. doi: 10.1073/pnas.1019164108. Epub 2011 Mar 28.


MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain.

Somel M, Guo S, Fu N, Yan Z, Hu HY, Xu Y, Yuan Y, Ning Z, Hu Y, Menzel C, Hu H, Lachmann M, Zeng R, Chen W, Khaitovich P.

Genome Res. 2010 Sep;20(9):1207-18. doi: 10.1101/gr.106849.110. Epub 2010 Jul 20.

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