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Results: 1 to 20 of 29

1.
2.

Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.

Ruan D, So SP.

Life Sci. 2014 Oct 22;116(1):43-50. doi: 10.1016/j.lfs.2014.07.042. Epub 2014 Aug 17.

PMID:
25139833
3.

Endothelial-like progenitor cells engineered to produce prostacyclin rescue monocrotaline-induced pulmonary arterial hypertension and provide right ventricle benefits.

Zhou L, Chen Z, Vanderslice P, So SP, Ruan KH, Willerson JT, Dixon RA.

Circulation. 2013 Aug 27;128(9):982-94. doi: 10.1161/CIRCULATIONAHA.113.003139. Epub 2013 Jul 10.

4.

Resistant to thrombosis, induced stroke and heart arrest by incorporation of a single gene of PGI2-synthesizing COX-1-PGIS in vivo: Implication against human heart disease.

Ruan KH, Mohite AJ, So SP.

Int J Cardiol. 2013 Oct 3;168(3):2960-1. doi: 10.1016/j.ijcard.2013.03.114. Epub 2013 Apr 18. No abstract available.

PMID:
23602873
5.
6.

Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells.

Liu Q, Xi Y, Terry T, So SP, Mohite A, Zhang J, Wu G, Liu X, Cheng J, Ruan KH, Willerson JT, Dixon RA.

J Cell Physiol. 2012 Jul;227(7):2907-16. doi: 10.1002/jcp.23035.

7.

Establishing novel prostacyclin-synthesizing cells with therapeutic potential against heart diseases.

Ruan KH, Mohite A, So SP, Ruan CH.

Int J Cardiol. 2013 Feb 20;163(2):163-9. doi: 10.1016/j.ijcard.2011.06.007. Epub 2011 Jun 30.

PMID:
21722977
8.

Novel mechanism of the vascular protector prostacyclin: regulating microRNA expression.

Mohite A, Chillar A, So SP, Cervantes V, Ruan KH.

Biochemistry. 2011 Mar 15;50(10):1691-9. doi: 10.1021/bi101654w. Epub 2011 Feb 20.

PMID:
21250659
9.

Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease.

Ruan CH, So SP, Ruan KH.

Life Sci. 2011 Jan 3;88(1-2):24-30. doi: 10.1016/j.lfs.2010.10.017. Epub 2010 Oct 28.

10.

A profile of NSAID-targeted arachidonic acid metabolisms in human embryonic stem cells (hESCs): implication of the negative effects of NSAIDs on heart tissue regeneration.

Chillar A, So SP, Ruan CH, Shelat H, Geng YJ, Ruan KH.

Int J Cardiol. 2011 Aug 4;150(3):253-9. doi: 10.1016/j.ijcard.2010.04.015. Epub 2010 May 7.

PMID:
20451268
11.
12.
13.

Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential.

Ruan KH, So SP, Wu H, Cervantes V.

Arch Biochem Biophys. 2008 Dec 1;480(1):41-50. doi: 10.1016/j.abb.2008.09.010. Epub 2008 Sep 22.

14.

Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis.

Chillar A, Wu J, So SP, Ruan KH.

FEBS Lett. 2008 Aug 20;582(19):2863-8. doi: 10.1016/j.febslet.2008.07.018. Epub 2008 Jul 22.

15.
16.

Efficacy of multidisciplinary approach in treatment of constipation: a pilot study.

Lau PY, Fung B, Meng WC, Leung R, Yip AW, So SP, Lee QS, Chan D.

Hong Kong Med J. 2006 Dec;12(6):415-8.

17.
19.

NMR structure of the thromboxane A2 receptor ligand recognition pocket.

Ruan KH, Wu J, So SP, Jenkins LA, Ruan CH.

Eur J Biochem. 2004 Jul;271(14):3006-16.

20.

Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor.

Geng L, Wu J, So SP, Huang G, Ruan KH.

Arch Biochem Biophys. 2004 Mar 15;423(2):253-65.

PMID:
15001390
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