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Results: 1 to 20 of 131

1.

Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits.

Pal B, Chen Y, Bert A, Hu Y, Sheridan JM, Beck T, Shi W, Satterley K, Jamieson P, Goodall GJ, Lindeman GJ, Smyth GK, Visvader JE.

Breast Cancer Res. 2015 Jun 18;17(1):85. doi: 10.1186/s13058-015-0585-0.

2.

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3.

Liu X, Liu R, Croker BA, Lawlor KE, Smyth GK, Wicks IP.

Osteoarthritis Cartilage. 2015 Jun 2. pii: S1063-4584(15)01168-1. doi: 10.1016/j.joca.2015.05.011. [Epub ahead of print]

PMID:
26045176
3.

Early lineage priming by trisomy of erg leads to myeloproliferation in a down syndrome model.

Ng AP, Hu Y, Metcalf D, Hyland CD, Ierino H, Phipson B, Wu D, Baldwin TM, Kauppi M, Kiu H, Di Rago L, Hilton DJ, Smyth GK, Alexander WS.

PLoS Genet. 2015 May 14;11(5):e1005211. doi: 10.1371/journal.pgen.1005211. eCollection 2015 May.

4.

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses.

Liu R, Holik AZ, Su S, Jansz N, Chen K, Leong HS, Blewitt ME, Asselin-Labat ML, Smyth GK, Ritchie ME.

Nucleic Acids Res. 2015 Apr 29. pii: gkv412. [Epub ahead of print]

5.

MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo.

Sheikh BN, Downer NL, Phipson B, Vanyai HK, Kueh AJ, McCarthy DJ, Smyth GK, Thomas T, Voss AK.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5437-42. doi: 10.1073/pnas.1422872112. Epub 2015 Apr 14.

6.

Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S, Fagarasan S, Mielke LA, Afshar-Sterle S, Masters SL, Nakae S, Saito H, Wentworth JM, Li P, Liao W, Leonard WJ, Smyth GK, Shi W, Nutt SL, Koyasu S, Kallies A.

Nat Immunol. 2015 May;16(5):544. doi: 10.1038/ni0515-544d. No abstract available.

PMID:
25898200
7.

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Shi W, Liao Y, Willis SN, Taubenheim N, Inouye M, Tarlinton DM, Smyth GK, Hodgkin PD, Nutt SL, Corcoran LM.

Nat Immunol. 2015 Jun;16(6):663-73. doi: 10.1038/ni.3154. Epub 2015 Apr 20.

PMID:
25894659
8.

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.

Sheridan JM, Ritchie ME, Best SA, Jiang K, Beck TJ, Vaillant F, Liu K, Dickins RA, Smyth GK, Lindeman GJ, Visvader JE.

BMC Cancer. 2015 Apr 3;15:221. doi: 10.1186/s12885-015-1187-z.

9.

MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway.

Sheikh BN, Phipson B, El-Saafin F, Vanyai HK, Downer NL, Bird MJ, Kueh AJ, May RE, Smyth GK, Voss AK, Thomas T.

Oncogene. 2015 Mar 16. doi: 10.1038/onc.2015.33. [Epub ahead of print]

PMID:
25772242
10.

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.

Fu NY, Rios AC, Pal B, Soetanto R, Lun AT, Liu K, Beck T, Best SA, Vaillant F, Bouillet P, Strasser A, Preiss T, Smyth GK, Lindeman GJ, Visvader JE.

Nat Cell Biol. 2015 Apr;17(4):365-75. doi: 10.1038/ncb3117. Epub 2015 Mar 2.

PMID:
25730472
11.

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.

Witkowski MT, Cimmino L, Hu Y, Trimarchi T, Tagoh H, McKenzie MD, Best SA, Tuohey L, Willson TA, Nutt SL, Busslinger M, Aifantis I, Smyth GK, Dickins RA.

Leukemia. 2015 Jun;29(6):1301-11. doi: 10.1038/leu.2015.27. Epub 2015 Feb 6.

PMID:
25655195
12.

Orchestrating high-throughput genomic analysis with Bioconductor.

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M.

Nat Methods. 2015 Feb;12(2):115-21. doi: 10.1038/nmeth.3252. Review.

13.

limma powers differential expression analyses for RNA-sequencing and microarray studies.

Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK.

Nucleic Acids Res. 2015 Apr 20;43(7):e47. doi: 10.1093/nar/gkv007. Epub 2015 Jan 20. Review.

14.

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.

Sheikh BN, Lee SC, El-Saafin F, Vanyai HK, Hu Y, Pang SH, Grabow S, Strasser A, Nutt SL, Alexander WS, Smyth GK, Voss AK, Thomas T.

Blood. 2015 Mar 19;125(12):1910-21. doi: 10.1182/blood-2014-08-594655. Epub 2015 Jan 20.

15.

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S, Fagarasan S, Mielke LA, Afshar-Sterle S, Masters SL, Nakae S, Saito H, Wentworth JM, Li P, Liao W, Leonard WJ, Smyth GK, Shi W, Nutt SL, Koyasu S, Kallies A.

Nat Immunol. 2015 Mar;16(3):276-85. doi: 10.1038/ni.3085. Epub 2015 Jan 19. Erratum in: Nat Immunol. 2015 May;16(5):544.

PMID:
25599561
16.

Peripheral natural killer cell maturation depends on the transcription factor Aiolos.

Holmes ML, Huntington ND, Thong RP, Brady J, Hayakawa Y, Andoniou CE, Fleming P, Shi W, Smyth GK, Degli-Esposti MA, Belz GT, Kallies A, Carotta S, Smyth MJ, Nutt SL.

EMBO J. 2014 Nov 18;33(22):2721-34. doi: 10.15252/embj.201487900. Epub 2014 Oct 15.

PMID:
25319415
17.

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures.

Munro SA, Lund SP, Pine PS, Binder H, Clevert DA, Conesa A, Dopazo J, Fasold M, Hochreiter S, Hong H, Jafari N, Kreil DP, Łabaj PP, Li S, Liao Y, Lin SM, Meehan J, Mason CE, Santoyo-Lopez J, Setterquist RA, Shi L, Shi W, Smyth GK, Stralis-Pavese N, Su Z, Tong W, Wang C, Wang J, Xu J, Ye Z, Yang Y, Yu Y, Salit M.

Nat Commun. 2014 Sep 25;5:5125. doi: 10.1038/ncomms6125.

PMID:
25254650
18.

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK, Kile BT, Medvinsky A, Alexander WS, Hilton DJ, Taoudi S.

Blood. 2014 Oct 23;124(17):2725-9. doi: 10.1182/blood-2014-02-559468. Epub 2014 Jul 25.

PMID:
25079356
19.

Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks.

Ling KH, Hewitt CA, Tan KL, Cheah PS, Vidyadaran S, Lai MI, Lee HC, Simpson K, Hyde L, Pritchard MA, Smyth GK, Thomas T, Scott HS.

BMC Genomics. 2014 Jul 22;15:624. doi: 10.1186/1471-2164-15-624.

20.

Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.

Good-Jacobson KL, Chen Y, Voss AK, Smyth GK, Thomas T, Tarlinton D.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9585-90. doi: 10.1073/pnas.1402485111. Epub 2014 Jun 16.

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