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Items: 1 to 20 of 29


Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency.

Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, Mikkelsen TS.

Cell. 2015 Jul 16;162(2):412-24. doi: 10.1016/j.cell.2015.06.016.


Epigenetic predisposition to reprogramming fates in somatic cells.

Pour M, Pilzer I, Rosner R, Smith ZD, Meissner A, Nachman I.

EMBO Rep. 2015 Mar;16(3):370-8. doi: 10.15252/embr.201439264. Epub 2015 Jan 18.


DNA methylation dynamics of the human preimplantation embryo.

Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A.

Nature. 2014 Jul 31;511(7511):611-5. doi: 10.1038/nature13581. Epub 2014 Jul 23.


In Vivo and in vitro dynamics of undifferentiated embryonic cell transcription factor 1.

Galonska C, Smith ZD, Meissner A.

Stem Cell Reports. 2014 Feb 20;2(3):245-52. doi: 10.1016/j.stemcr.2014.01.007. eCollection 2014 Mar 11.


Tet1 regulates adult hippocampal neurogenesis and cognition.

Zhang RR, Cui QY, Murai K, Lim YC, Smith ZD, Jin S, Ye P, Rosa L, Lee YK, Wu HP, Liu W, Xu ZM, Yang L, Ding YQ, Tang F, Meissner A, Ding C, Shi Y, Xu GL.

Cell Stem Cell. 2013 Aug 1;13(2):237-45. doi: 10.1016/j.stem.2013.05.006. Epub 2013 Jun 13.


Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ.

Cell Stem Cell. 2013 Apr 4;12(4):413-25. doi: 10.1016/j.stem.2013.01.017. Epub 2013 Feb 14.


DNA methylation: roles in mammalian development.

Smith ZD, Meissner A.

Nat Rev Genet. 2013 Mar;14(3):204-20. doi: 10.1038/nrg3354. Epub 2013 Feb 12. Review.


The simplest explanation: passive DNA demethylation in PGCs.

Smith ZD, Meissner A.

EMBO J. 2013 Feb 6;32(3):318-21. doi: 10.1038/emboj.2012.349. Epub 2013 Jan 8. No abstract available.


Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling.

Boyle P, Clement K, Gu H, Smith ZD, Ziller M, Fostel JL, Holmes L, Meldrim J, Kelley F, Gnirke A, Meissner A.

Genome Biol. 2012 Oct 3;13(10):R92. doi: 10.1186/gb-2012-13-10-r92.


Mouse ooplasm confers context-specific reprogramming capacity.

Chan MM, Smith ZD, Egli D, Regev A, Meissner A.

Nat Genet. 2012 Sep;44(9):978-80. doi: 10.1038/ng.2382. Epub 2012 Aug 19.


DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.

Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A.

Mol Cell. 2012 Aug 24;47(4):633-47. doi: 10.1016/j.molcel.2012.06.019. Epub 2012 Jul 26.


A unique regulatory phase of DNA methylation in the early mammalian embryo.

Smith ZD, Chan MM, Mikkelsen TS, Gu H, Gnirke A, Regev A, Meissner A.

Nature. 2012 Mar 28;484(7394):339-44. doi: 10.1038/nature10960.


Epigenomics and chromatin dynamics.

Akopian V, Chan MM, Clement K, Galonska C, Gifford CA, Lehtola E, Liao J, Samavarchi-Tehrani P, Sindhu C, Smith ZD, Tsankov AM, Webster J, Zhang Y, Ziller MJ, Meissner A.

Genome Biol. 2012 Feb 24;13(2):313. doi: 10.1186/gb-2012-13-2-313.


Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.

Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW, Zamponi R, Gazit R, Bock C, Jäger N, Smith ZD, Kim TM, Saunders AH, Wong J, Lee JH, Roach RR, Rossi DJ, Meissner A, Gimelbrant AA, Park PJ, Kim CF.

Cell Stem Cell. 2011 Sep 2;9(3):272-81. doi: 10.1016/j.stem.2011.07.007.


Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.

Gu H, Smith ZD, Bock C, Boyle P, Gnirke A, Meissner A.

Nat Protoc. 2011 Apr;6(4):468-81. doi: 10.1038/nprot.2010.190. Epub 2011 Mar 18.


Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.

Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith ZD, Ziller M, Croft GF, Amoroso MW, Oakley DH, Gnirke A, Eggan K, Meissner A.

Cell. 2011 Feb 4;144(3):439-52. doi: 10.1016/j.cell.2010.12.032.


Reprogramming factor expression initiates widespread targeted chromatin remodeling.

Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A.

Cell Stem Cell. 2011 Jan 7;8(1):96-105. doi: 10.1016/j.stem.2010.12.001.


Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ.

Cell Stem Cell. 2010 Nov 5;7(5):618-30. doi: 10.1016/j.stem.2010.08.012. Epub 2010 Sep 30.


Dynamic single-cell imaging of direct reprogramming reveals an early specifying event.

Smith ZD, Nachman I, Regev A, Meissner A.

Nat Biotechnol. 2010 May;28(5):521-6. doi: 10.1038/nbt.1632. Epub 2010 May 2.


Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.

Gu H, Bock C, Mikkelsen TS, Jäger N, Smith ZD, Tomazou E, Gnirke A, Lander ES, Meissner A.

Nat Methods. 2010 Feb;7(2):133-6. doi: 10.1038/nmeth.1414. Epub 2010 Jan 10.

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