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Results: 1 to 20 of 99

1.

Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency.

Felgentreff K, Lee YN, Frugoni F, Du L, van der Burg M, Giliani S, Tezcan I, Reisli I, Mejstrikova E, de Villartay JP, Sleckman BP, Manis J, Notarangelo LD.

J Allergy Clin Immunol. 2015 Jul;136(1):140-150.e7. doi: 10.1016/j.jaci.2015.03.005. Epub 2015 Apr 25.

PMID:
25917813
2.

DNA damage responses: beyond double-strand break repair.

Bredemeyer AL, Sleckman BP.

Curr Biol. 2015 Jan 5;25(1):R45-6. doi: 10.1016/j.cub.2014.11.024.

PMID:
25562302
3.

ATM deficiency: revealing the pathways to cancer.

Tubbs AT, Sleckman BP.

Cell Cycle. 2014;13(19):2992. doi: 10.4161/15384101.2014.959849. No abstract available.

PMID:
25486558
4.

HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution.

Dorsett Y, Zhou Y, Tubbs AT, Chen BR, Purman C, Lee BS, George R, Bredemeyer AL, Zhao JY, Sodergen E, Weinstock GM, Han ND, Reyes A, Oltz EM, Dorsett D, Misulovin Z, Payton JE, Sleckman BP.

Mol Cell. 2014 Dec 18;56(6):808-18. doi: 10.1016/j.molcel.2014.10.024. Epub 2014 Nov 26.

PMID:
25435138
5.

KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.

Tubbs AT, Dorsett Y, Chan E, Helmink B, Lee BS, Hung P, George R, Bredemeyer AL, Mittal A, Pappu RV, Chowdhury D, Mosammaparast N, Krangel MS, Sleckman BP.

Mol Cell Biol. 2014 Aug;34(15):2811-21. doi: 10.1128/MCB.00441-14. Epub 2014 May 19.

6.

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.

Makharashvili N, Tubbs AT, Yang SH, Wang H, Barton O, Zhou Y, Deshpande RA, Lee JH, Lobrich M, Sleckman BP, Wu X, Paull TT.

Mol Cell. 2014 Jun 19;54(6):1022-33. doi: 10.1016/j.molcel.2014.04.011. Epub 2014 May 15.

7.

Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response.

Ehninger A, Boch T, Uckelmann H, Essers MA, Müdder K, Sleckman BP, Trumpp A.

Blood. 2014 Jun 19;123(25):3909-13. doi: 10.1182/blood-2013-10-531038. Epub 2014 May 2.

8.

L-Myc expression by dendritic cells is required for optimal T-cell priming.

KC W, Satpathy AT, Rapaport AS, Briseño CG, Wu X, Albring JC, Russler-Germain EV, Kretzer NM, Durai V, Persaud SP, Edelson BT, Loschko J, Cella M, Allen PM, Nussenzweig MC, Colonna M, Sleckman BP, Murphy TL, Murphy KM.

Nature. 2014 Mar 13;507(7491):243-7. doi: 10.1038/nature12967. Epub 2014 Feb 9.

9.

β-Catenin induces T-cell transformation by promoting genomic instability.

Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):391-6. doi: 10.1073/pnas.1315752111. Epub 2013 Dec 26.

10.

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, Sleckman BP.

Mol Cell Biol. 2013 Sep;33(18):3568-79. doi: 10.1128/MCB.00308-13. Epub 2013 Jul 8.

11.

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, Ge K, Alt FW, Fernandez-Capetillo O, Nussenzweig MC, Nussenzweig A.

Cell. 2013 Jun 6;153(6):1266-80. doi: 10.1016/j.cell.2013.05.023. Epub 2013 May 30.

12.

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.

Um JH, Brown AL, Singh SK, Chen Y, Gucek M, Lee BS, Luckey MA, Kim MK, Park JH, Sleckman BP, Gellert M, Chung JH.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9873-8. doi: 10.1073/pnas.1307928110. Epub 2013 May 28.

13.

DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.

Innes CL, Hesse JE, Palii SS, Helmink BA, Holub AJ, Sleckman BP, Paules RS.

BMC Genomics. 2013 Mar 12;14:163. doi: 10.1186/1471-2164-14-163.

14.

The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination.

Lee BS, Dekker JD, Lee BK, Iyer VR, Sleckman BP, Shaffer AL 3rd, Ippolito GC, Tucker PW.

Mol Cell Biol. 2013 May;33(9):1768-81. doi: 10.1128/MCB.00987-12. Epub 2013 Feb 25.

15.

Cutting edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cells.

Sandoval GJ, Graham DB, Bhattacharya D, Sleckman BP, Xavier RJ, Swat W.

J Immunol. 2013 Mar 15;190(6):2485-9. doi: 10.4049/jimmunol.1203208. Epub 2013 Feb 18.

16.

The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements.

Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH.

J Exp Med. 2013 Feb 11;210(2):233-9. doi: 10.1084/jem.20121605. Epub 2013 Feb 4.

17.

Lymphocyte development: integration of DNA damage response signaling.

Bednarski JJ, Sleckman BP.

Adv Immunol. 2012;116:175-204. doi: 10.1016/B978-0-12-394300-2.00006-5. Review.

18.

Integrated signaling in developing lymphocytes: the role of DNA damage responses.

Bednarski JJ, Sleckman BP.

Cell Cycle. 2012 Nov 15;11(22):4129-34. doi: 10.4161/cc.22021. Epub 2012 Oct 3.

19.

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.

Calado DP, Sasaki Y, Godinho SA, Pellerin A, Köchert K, Sleckman BP, de Alborán IM, Janz M, Rodig S, Rajewsky K.

Nat Immunol. 2012 Nov;13(11):1092-100. doi: 10.1038/ni.2418. Epub 2012 Sep 23.

20.

Loss of ATM kinase activity leads to embryonic lethality in mice.

Daniel JA, Pellegrini M, Lee BS, Guo Z, Filsuf D, Belkina NV, You Z, Paull TT, Sleckman BP, Feigenbaum L, Nussenzweig A.

J Cell Biol. 2012 Aug 6;198(3):295-304. doi: 10.1083/jcb.201204035.

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