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Items: 1 to 20 of 22

1.

Paroxetine suppresses recombinant human P2X7 responses.

Dao-Ung P, Skarratt KK, Fuller SJ, Stokes L.

Purinergic Signal. 2015 Dec;11(4):481-90. doi: 10.1007/s11302-015-9467-2. Epub 2015 Sep 5.

2.

R270C polymorphism leads to loss of function of the canine P2X7 receptor.

Spildrejorde M, Bartlett R, Stokes L, Jalilian I, Peranec M, Sluyter V, Curtis BL, Skarratt KK, Skora A, Bakhsh T, Seavers A, McArthur JD, Dowton M, Sluyter R.

Physiol Genomics. 2014 Jul 15;46(14):512-22. doi: 10.1152/physiolgenomics.00195.2013. Epub 2014 May 13.

3.

Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism.

Bhaskaracharya A, Dao-Ung P, Jalilian I, Spildrejorde M, Skarratt KK, Fuller SJ, Sluyter R, Stokes L.

PLoS One. 2014 Mar 26;9(3):e93058. doi: 10.1371/journal.pone.0093058. eCollection 2014.

4.

Quantitative real-time PCR eliminates false-positives in colony screening PCR.

Skarratt KK, Fuller SJ.

J Microbiol Methods. 2014 Jan;96:99-100. doi: 10.1016/j.mimet.2013.11.011. Epub 2013 Dec 1.

PMID:
24291202
5.

A quantitative method for measuring innate phagocytosis by human monocytes using real-time flow cytometry.

Gu BJ, Sun C, Fuller S, Skarratt KK, Petrou S, Wiley JS.

Cytometry A. 2014 Apr;85(4):313-21. doi: 10.1002/cyto.a.22400. Epub 2013 Oct 16.

6.

Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.

Lester S, Stokes L, Skarratt KK, Gu BJ, Sivils KL, Lessard CJ, Wiley JS, Rischmueller M.

Arthritis Res Ther. 2013 Jun 2;15(4):R71. doi: 10.1186/ar4248.

7.

A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration.

Gu BJ, Baird PN, Vessey KA, Skarratt KK, Fletcher EL, Fuller SJ, Richardson AJ, Guymer RH, Wiley JS.

FASEB J. 2013 Apr;27(4):1479-87. doi: 10.1096/fj.12-215368. Epub 2013 Jan 9.

8.

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures.

Jørgensen NR, Husted LB, Skarratt KK, Stokes L, Tofteng CL, Kvist T, Jensen JE, Eiken P, Brixen K, Fuller S, Clifton-Bligh R, Gartland A, Schwarz P, Langdahl BL, Wiley JS.

Eur J Hum Genet. 2012 Jun;20(6):675-81. doi: 10.1038/ejhg.2011.253. Epub 2012 Jan 25.

9.

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women.

Gartland A, Skarratt KK, Hocking LJ, Parsons C, Stokes L, Jørgensen NR, Fraser WD, Reid DM, Gallagher JA, Wiley JS.

Eur J Hum Genet. 2012 May;20(5):559-64. doi: 10.1038/ejhg.2011.245. Epub 2012 Jan 11.

10.

A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure.

Stokes L, Scurrah K, Ellis JA, Cromer BA, Skarratt KK, Gu BJ, Harrap SB, Wiley JS.

Hypertension. 2011 Dec;58(6):1086-92. doi: 10.1161/HYPERTENSIONAHA.111.176180. Epub 2011 Nov 7.

11.

Functional significance of P2RX7 polymorphisms associated with affective mood disorders.

Sluyter R, Stokes L, Fuller SJ, Skarratt KK, Gu BJ, Wiley JS.

J Psychiatr Res. 2010 Nov;44(15):1116-7. doi: 10.1016/j.jpsychires.2010.04.013. Epub 2010 May 11. No abstract available.

PMID:
20462595
12.

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion.

Stokes L, Fuller SJ, Sluyter R, Skarratt KK, Gu BJ, Wiley JS.

FASEB J. 2010 Aug;24(8):2916-27. doi: 10.1096/fj.09-150862. Epub 2010 Apr 1.

13.

Identification of the promoter region of the P2RX4 gene.

Gu BJ, Sun C, Valova VA, Skarratt KK, Wiley JS.

Mol Biol Rep. 2010 Oct;37(7):3369-76. doi: 10.1007/s11033-009-9924-5. Epub 2009 Dec 2.

PMID:
19953327
14.

Genetics of the P2X7 receptor and human disease.

Fuller SJ, Stokes L, Skarratt KK, Gu BJ, Wiley JS.

Purinergic Signal. 2009 Jun;5(2):257-62. doi: 10.1007/s11302-009-9136-4. Epub 2009 Mar 25.

15.

Analysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemia.

Fuller SJ, Papaemmanuil E, McKinnon L, Webb E, Sellick GS, Dao-Ung LP, Skarratt KK, Crowther D, Houlston RS, Wiley JS.

Br J Haematol. 2008 Jun;142(2):238-45. doi: 10.1111/j.1365-2141.2008.07188.x. Epub 2008 May 22.

PMID:
18503587
16.

A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis.

Fernando SL, Saunders BM, Sluyter R, Skarratt KK, Goldberg H, Marks GB, Wiley JS, Britton WJ.

Am J Respir Crit Care Med. 2007 Feb 15;175(4):360-6. Epub 2006 Nov 9.

PMID:
17095747
17.

A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages.

Shemon AN, Sluyter R, Fernando SL, Clarke AL, Dao-Ung LP, Skarratt KK, Saunders BM, Tan KS, Gu BJ, Fuller SJ, Britton WJ, Petrou S, Wiley JS.

J Biol Chem. 2006 Jan 27;281(4):2079-86. Epub 2005 Nov 1.

18.

Human epidermal and monocyte-derived langerhans cells express functional P2X receptors.

Georgiou JG, Skarratt KK, Fuller SJ, Martin CJ, Christopherson RI, Wiley JS, Sluyter R.

J Invest Dermatol. 2005 Sep;125(3):482-90.

19.

Gene dosage determines the negative effects of polymorphic alleles of the P2X7 receptor on adenosine triphosphate-mediated killing of mycobacteria by human macrophages.

Fernando SL, Saunders BM, Sluyter R, Skarratt KK, Wiley JS, Britton WJ.

J Infect Dis. 2005 Jul 1;192(1):149-55. Epub 2005 May 31.

20.

A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.

Skarratt KK, Fuller SJ, Sluyter R, Dao-Ung LP, Gu BJ, Wiley JS.

FEBS Lett. 2005 May 9;579(12):2675-8. Epub 2005 Apr 14.

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