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Results: 1 to 20 of 34

1.

Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer.

Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A.

Oncotarget. 2015 May 20;6(14):12436-51.

2.

Photochemical internalization of tamoxifens transported by a "Trojan-horse" nanoconjugate into breast-cancer cell lines.

Theodossiou TA, Gonçalves AR, Yannakopoulou K, Skarpen E, Berg K.

Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4885-9. doi: 10.1002/anie.201500183. Epub 2015 Feb 6.

PMID:
25663536
3.

Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome.

Bull-Hansen B, Cao Y, Berg K, Skarpen E, Rosenblum MG, Weyergang A.

J Control Release. 2014 May 28;182:58-66. doi: 10.1016/j.jconrel.2014.03.014. Epub 2014 Mar 15.

PMID:
24637464
4.

The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines.

Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK.

MAbs. 2014 Jul-Aug;6(4):1038-50.

5.

EGF activates autocrine TGFα to induce prolonged egf receptor signaling and hepatocyte proliferation.

Liu S, Wierød L, Skarpen E, Grøsvik H, Duan G, Huitfeldt HS.

Cell Physiol Biochem. 2013;32(3):511-22. doi: 10.1159/000354454. Epub 2013 Aug 30.

PMID:
24008581
6.

Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity.

Stratford EW, Bostad M, Castro R, Skarpen E, Berg K, Høgset A, Myklebost O, Selbo PK.

Biochim Biophys Acta. 2013 Aug;1830(8):4235-43. doi: 10.1016/j.bbagen.2013.04.033. Epub 2013 May 2.

PMID:
23643966
7.

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties.

Bostad M, Berg K, Høgset A, Skarpen E, Stenmark H, Selbo PK.

J Control Release. 2013 Jun 28;168(3):317-26. doi: 10.1016/j.jconrel.2013.03.023. Epub 2013 Apr 6.

PMID:
23567040
8.

FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes.

Flinder LI, Wierød L, Rosseland CM, Huitfeldt HS, Skarpen E.

J Cell Physiol. 2013 Jun;228(6):1304-13. doi: 10.1002/jcp.24287.

PMID:
23168795
9.

The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion.

Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H.

Traffic. 2012 Nov;13(11):1547-63. doi: 10.1111/j.1600-0854.2012.01400.x. Epub 2012 Aug 8.

PMID:
22816767
10.

EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase.

Flinder LI, Timofeeva OA, Rosseland CM, Wierød L, Huitfeldt HS, Skarpen E.

J Cell Physiol. 2011 Sep;226(9):2267-78. doi: 10.1002/jcp.22563.

PMID:
21660950
11.

Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit.

Oksvold MP, Funderud A, Kvissel AK, Skarpen E, Henanger H, Huitfeldt HS, Skålhegg BS, Ørstavik S.

BMC Cell Biol. 2008 Apr 1;9:16. doi: 10.1186/1471-2121-9-16.

12.

Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K.

Rosseland CM, Wierød L, Flinder LI, Oksvold MP, Skarpen E, Huitfeldt HS.

J Cell Physiol. 2008 Jun;215(3):818-26. doi: 10.1002/jcp.21367.

PMID:
18163378
13.

Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes.

Wierød L, Rosseland CM, Lindeman B, Oksvold MP, Grøsvik H, Skarpen E, Huitfeldt HS.

Oncogene. 2008 Apr 24;27(19):2763-71. Epub 2007 Nov 19.

PMID:
18026139
14.

MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.

Skarpen E, Flinder LI, Rosseland CM, Orstavik S, Wierød L, Oksvold MP, Skålhegg BS, Huitfeldt HS.

FASEB J. 2008 Feb;22(2):466-76. Epub 2007 Oct 10.

15.

CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes.

Wierød L, Rosseland CM, Lindeman B, Oksvold MP, Grøsvik H, Skarpen E, Huitfeldt HS.

Cell Prolif. 2007 Aug;40(4):475-87.

PMID:
17635516
16.

Regulation of rat alveolar type 2 cell proliferation in vitro involves type II cAMP-dependent protein kinase.

Samuelsen JT, Schwarze PE, Huitfeldt HS, Thrane EV, Låg M, Refsnes M, Skarpen E, Becher R.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L232-9. Epub 2006 Sep 15.

17.

Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes.

Rosseland CM, Wierød L, Oksvold MP, Werner H, Ostvold AC, Thoresen GH, Paulsen RE, Huitfeldt HS, Skarpen E.

Hepatology. 2005 Jul;42(1):200-7.

PMID:
15962331
18.

Altered regulation of EGF receptor signaling following a partial hepatectomy.

Skarpen E, Oksvold MP, Grøsvik H, Widnes C, Huitfeldt HS.

J Cell Physiol. 2005 Mar;202(3):707-16.

PMID:
15389569
19.

UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor.

Oksvold MP, Huitfeldt HS, Østvold AC, Skarpen E.

J Cell Sci. 2002 Feb 15;115(Pt 4):793-803.

20.

Fluorescent histochemical techniques for analysis of intracellular signaling.

Oksvold MP, Skarpen E, Widerberg J, Huitfeldt HS.

J Histochem Cytochem. 2002 Mar;50(3):289-303. Review.

PMID:
11850432
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