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Results: 1 to 20 of 48

1.

Increased STAT1 signaling in endocrine-resistant breast cancer.

Huang R, Faratian D, Sims AH, Wilson D, Thomas JS, Harrison DJ, Langdon SP.

PLoS One. 2014 Apr 11;9(4):e94226. doi: 10.1371/journal.pone.0094226. eCollection 2014.

PMID:
24728078
[PubMed - in process]
Free PMC Article
2.

Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2.

Gray TA, Alsamman K, Murray E, Sims AH, Hupp TR.

Mol Biosyst. 2014 Jun;10(6):1409-25. doi: 10.1039/c4mb00113c. Epub 2014 Apr 7.

PMID:
24710632
[PubMed - in process]
3.

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity.

Ablett MP, O'Brien CS, Sims AH, Farnie G, Clarke RB.

Oncotarget. 2014 Feb 15;5(3):599-612.

PMID:
24583601
[PubMed - in process]
Free PMC Article
4.

Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.

Lehn S, Tobin NP, Sims AH, Stål O, Jirström K, Axelson H, Landberg G.

BMC Cancer. 2014 Feb 22;14:119. doi: 10.1186/1471-2407-14-119.

PMID:
24559095
[PubMed - in process]
Free PMC Article
5.

Modulation of strain-specific differences in gene expression by cannabinoid type 2 receptor deficiency.

Sophocleous A, Sims AH, Idris AI, Ralston SH.

Calcif Tissue Int. 2014 Apr;94(4):423-32. doi: 10.1007/s00223-013-9823-6. Epub 2013 Dec 27.

PMID:
24370613
[PubMed - in process]
6.

Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.

Keune WJ, Sims AH, Jones DR, Bultsma Y, Lynch JT, Jirström K, Landberg G, Divecha N.

Cancer Res. 2013 Dec 1;73(23):6913-25. doi: 10.1158/0008-5472.CAN-13-0424. Epub 2013 Oct 14.

PMID:
24127122
[PubMed - indexed for MEDLINE]
7.

Use of microarray analysis to investigate EMT gene signatures.

Sims AH, Larionov AA, Harrison DJ, Katz E.

Methods Mol Biol. 2013;1046:85-95. doi: 10.1007/978-1-62703-538-5_5.

PMID:
23868583
[PubMed - indexed for MEDLINE]
8.

Wnt pathway activity in breast cancer sub-types and stem-like cells.

Lamb R, Ablett MP, Spence K, Landberg G, Sims AH, Clarke RB.

PLoS One. 2013 Jul 4;8(7):e67811. doi: 10.1371/journal.pone.0067811. Print 2013.

PMID:
23861811
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer.

Loi S, Michiels S, Baselga J, Bartlett JM, Singhal SK, Sabine VS, Sims AH, Sahmoud T, Dixon JM, Piccart MJ, Sotiriou C.

PLoS One. 2013;8(1):e53292. doi: 10.1371/journal.pone.0053292. Epub 2013 Jan 2.

PMID:
23301057
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcript and protein profiling identifies signaling, growth arrest, apoptosis, and NF-κB survival signatures following GNRH receptor activation.

Meyer C, Sims AH, Morgan K, Harrison B, Muir M, Bai J, Faratian D, Millar RP, Langdon SP.

Endocr Relat Cancer. 2013 Feb 18;20(1):123-36. doi: 10.1530/ERC-12-0192. Print 2013 Feb.

PMID:
23202794
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns.

Sproul D, Kitchen RR, Nestor CE, Dixon JM, Sims AH, Harrison DJ, Ramsahoye BH, Meehan RR.

Genome Biol. 2012 Oct 3;13(10):R84. [Epub ahead of print]

PMID:
23034185
[PubMed - as supplied by publisher]
Free PMC Article
12.

Feedforward and feedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer.

Hu H, Goltsov A, Bown JL, Sims AH, Langdon SP, Harrison DJ, Faratian D.

Cell Signal. 2013 Jan;25(1):26-32. doi: 10.1016/j.cellsig.2012.09.014. Epub 2012 Sep 18.

PMID:
23000339
[PubMed - indexed for MEDLINE]
13.

Direct integration of intensity-level data from Affymetrix and Illumina microarrays improves statistical power for robust reanalysis.

Turnbull AK, Kitchen RR, Larionov AA, Renshaw L, Dixon JM, Sims AH.

BMC Med Genomics. 2012 Aug 21;5:35. doi: 10.1186/1755-8794-5-35.

PMID:
22909195
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells.

Wang B, Lindley LE, Fernandez-Vega V, Rieger ME, Sims AH, Briegel KJ.

PLoS One. 2012;7(7):e41355. doi: 10.1371/journal.pone.0041355. Epub 2012 Jul 23.

PMID:
22844464
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Targeting of Rac GTPases blocks the spread of intact human breast cancer.

Katz E, Sims AH, Sproul D, Caldwell H, Dixon MJ, Meehan RR, Harrison DJ.

Oncotarget. 2012 Jun;3(6):608-19.

PMID:
22689141
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals.

Moleirinho S, Chang N, Sims AH, Tilston-Lünel AM, Angus L, Steele A, Boswell V, Barnett SC, Ormandy C, Faratian D, Gunn-Moore FJ, Reynolds PA.

Oncogene. 2013 Apr 4;32(14):1821-30. doi: 10.1038/onc.2012.196. Epub 2012 May 21.

PMID:
22614006
[PubMed - indexed for MEDLINE]
17.

FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.

Goldie SJ, Mulder KW, Tan DW, Lyons SK, Sims AH, Watt FM.

Cancer Res. 2012 Jul 1;72(13):3424-36. doi: 10.1158/0008-5472.CAN-12-0423. Epub 2012 May 7.

PMID:
22564525
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer.

Sims AH, Zweemer AJ, Nagumo Y, Faratian D, Muir M, Dodds M, Um I, Kay C, Hasmann M, Harrison DJ, Langdon SP.

Br J Cancer. 2012 May 22;106(11):1779-89. doi: 10.1038/bjc.2012.176. Epub 2012 May 1.

PMID:
22549178
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Relative impact of key sources of systematic noise in Affymetrix and Illumina gene-expression microarray experiments.

Kitchen RR, Sabine VS, Simen AA, Dixon JM, Bartlett JM, Sims AH.

BMC Genomics. 2011 Dec 1;12:589. doi: 10.1186/1471-2164-12-589.

PMID:
22133085
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines.

Morgan K, Meyer C, Miller N, Sims AH, Cagnan I, Faratian D, Harrison DJ, Millar RP, Langdon SP.

BMC Cancer. 2011 Nov 3;11:476. doi: 10.1186/1471-2407-11-476.

PMID:
22051164
[PubMed - indexed for MEDLINE]
Free PMC Article

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