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Items: 1 to 20 of 83

1.

rAAV-compatible MiniPromoters for restricted expression in the brain and eye.

de Leeuw CN, Korecki AJ, Berry GE, Hickmott JW, Lam SL, Lengyell TC, Bonaguro RJ, Borretta LJ, Chopra V, Chou AY, D'Souza CA, Kaspieva O, Laprise S, McInerny SC, Portales-Casamar E, Swanson-Newman MI, Wong K, Yang GS, Zhou M, Jones SJ, Holt RA, Asokan A, Goldowitz D, Wasserman WW, Simpson EM.

Mol Brain. 2016 May 10;9(1):52. doi: 10.1186/s13041-016-0232-4.

2.

Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness.

Scalabrino ML, Boye SL, Fransen KM, Noel JM, Dyka FM, Min SH, Ruan Q, De Leeuw CN, Simpson EM, Gregg RG, McCall MA, Peachey NS, Boye SE.

Hum Mol Genet. 2015 Nov 1;24(21):6229-39. doi: 10.1093/hmg/ddv341. Epub 2015 Aug 26.

PMID:
26310623
3.

Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development.

Schmouth JF, Arenillas D, Corso-Díaz X, Xie YY, Bohacec S, Banks KG, Bonaguro RJ, Wong SH, Jones SJ, Marra MA, Simpson EM, Wasserman WW.

BMC Genomics. 2015 Jul 24;16:545. doi: 10.1186/s12864-015-1770-3.

4.
5.

Pulmonary artery dissection in eight dogs with patent ductus arteriosus.

Scansen BA, Simpson EM, López-Alvarez J, Thomas WP, Bright JM, Eason BD, Rush JE, Dukes-McEwan J, Green HW 3rd, Cunningham SM, Visser LC, Kent AM, Schober KE.

J Vet Cardiol. 2015 Jun;17(2):107-19. doi: 10.1016/j.jvc.2014.12.001. Epub 2015 Jan 14.

PMID:
25596918
6.

Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery.

Li H, Miteva M, Kirkbride KC, Cheng MJ, Nelson CE, Simpson EM, Gupta MK, Duvall CL, Giorgio TD.

Biomacromolecules. 2015 Jan 12;16(1):192-201. doi: 10.1021/bm501394m. Epub 2014 Dec 19.

7.

Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.

de Leeuw CN, Dyka FM, Boye SL, Laprise S, Zhou M, Chou AY, Borretta L, McInerny SC, Banks KG, Portales-Casamar E, Swanson MI, D'Souza CA, Boye SE, Jones SJ, Holt RA, Goldowitz D, Hauswirth WW, Wasserman WW, Simpson EM.

Mol Ther Methods Clin Dev. 2014 Jan 8;1:5.

8.

Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.

Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, Portales-Casamar E, Wilson G, Dreolini L, Jones SJ, Wasserman WW, Goldowitz D, Holt RA, Simpson EM.

BMC Biol. 2013 Oct 14;11:106. doi: 10.1186/1741-7007-11-106.

9.

Absence of NR2E1 mutations in patients with aniridia.

Corso-Díaz X, Borrie AE, Bonaguro R, Schuetz JM, Rosenberg T, Jensen H, Brooks BP, Macdonald IM, Pasutto F, Walter MA, Grønskov K, Brooks-Wilson A, Simpson EM.

Mol Vis. 2012;18:2770-82. Epub 2012 Nov 22.

10.

Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing.

Yang C, McLeod AJ, Cotton AM, de Leeuw CN, Laprise S, Banks KG, Simpson EM, Brown CJ.

Genetics. 2012 Dec;192(4):1281-93. doi: 10.1534/genetics.112.143743. Epub 2012 Sep 28.

11.

The mammalian gene function resource: the International Knockout Mouse Consortium.

Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W.

Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.

12.

Control of terrestrial animal rabies in Anne Arundel County, Maryland, after oral vaccination of raccoons (1998-2007).

Horman JT, Shannon KV, Simpson EM, Burja TM, Fey RH, Smith JJ, Phillips FB.

J Am Vet Med Assoc. 2012 Sep 15;241(6):725-34. doi: 10.2460/javma.241.6.725.

PMID:
22947155
13.

Beyond knockouts: cre resources for conditional mutagenesis.

Murray SA, Eppig JT, Smedley D, Simpson EM, Rosenthal N.

Mamm Genome. 2012 Oct;23(9-10):587-99. doi: 10.1007/s00335-012-9430-2. Epub 2012 Aug 29. Erratum in: Mamm Genome. 2012 Dec;23(11-12):791.

14.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

15.

Modelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencing.

Schmouth JF, Bonaguro RJ, Corso-Diaz X, Simpson EM.

PLoS Genet. 2012;8(3):e1002544. doi: 10.1371/journal.pgen.1002544. Epub 2012 Mar 1. Review.

16.

Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice.

Schmouth JF, Banks KG, Mathelier A, Gregory-Evans CY, Castellarin M, Holt RA, Gregory-Evans K, Wasserman WW, Simpson EM.

Mol Cell Biol. 2012 Apr;32(7):1296-311. doi: 10.1128/MCB.06016-11. Epub 2012 Jan 30.

17.

A rare cause of ear pain in a young boy.

Oliver AM, Simpson EM, Jerath RS.

J Pediatr. 2012 Feb;160(2):350. doi: 10.1016/j.jpeds.2011.08.030. Epub 2011 Oct 13. No abstract available.

PMID:
22000301
18.

A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro.

Aubrecht J, Goad ME, Czopik AK, Lerner CP, Johnson KA, Simpson EM, Schiestl RH.

Drug Chem Toxicol. 2011 Oct;34(4):433-9. doi: 10.3109/01480545.2010.544316. Epub 2011 Jul 11.

PMID:
21740348
19.

Kinematic and behavioral evidence for a distinction between trotting and ambling gaits in the cockroach Blaberus discoidalis.

Bender JA, Simpson EM, Tietz BR, Daltorio KA, Quinn RD, Ritzmann RE.

J Exp Biol. 2011 Jun 15;214(Pt 12):2057-64. doi: 10.1242/jeb.056481.

20.

Computer-assisted 3D kinematic analysis of all leg joints in walking insects.

Bender JA, Simpson EM, Ritzmann RE.

PLoS One. 2010 Oct 26;5(10):e13617. doi: 10.1371/journal.pone.0013617.

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