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Results: 1 to 20 of 77

1.

Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.

de Leeuw CN, Dyka FM, Boye SL, Laprise S, Zhou M, Chou AY, Borretta L, McInerny SC, Banks KG, Portales-Casamar E, Swanson MI, D'Souza CA, Boye SE, Jones SJ, Holt RA, Goldowitz D, Hauswirth WW, Wasserman WW, Simpson EM.

Mol Ther Methods Clin Dev. 2014 Jan 8;1:5.

PMID:
24761428
[PubMed]
Free PMC Article
2.

Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.

Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, Portales-Casamar E, Wilson G, Dreolini L, Jones SJ, Wasserman WW, Goldowitz D, Holt RA, Simpson EM.

BMC Biol. 2013 Oct 14;11:106. doi: 10.1186/1741-7007-11-106.

PMID:
24124870
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Absence of NR2E1 mutations in patients with aniridia.

Corso-Díaz X, Borrie AE, Bonaguro R, Schuetz JM, Rosenberg T, Jensen H, Brooks BP, Macdonald IM, Pasutto F, Walter MA, Grønskov K, Brooks-Wilson A, Simpson EM.

Mol Vis. 2012;18:2770-82. Epub 2012 Nov 22.

PMID:
23213277
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing.

Yang C, McLeod AJ, Cotton AM, de Leeuw CN, Laprise S, Banks KG, Simpson EM, Brown CJ.

Genetics. 2012 Dec;192(4):1281-93. doi: 10.1534/genetics.112.143743. Epub 2012 Sep 28.

PMID:
23023002
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The mammalian gene function resource: the International Knockout Mouse Consortium.

Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W.

Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.

PMID:
22968824
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Control of terrestrial animal rabies in Anne Arundel County, Maryland, after oral vaccination of raccoons (1998-2007).

Horman JT, Shannon KV, Simpson EM, Burja TM, Fey RH, Smith JJ, Phillips FB.

J Am Vet Med Assoc. 2012 Sep 15;241(6):725-34. doi: 10.2460/javma.241.6.725.

PMID:
22947155
[PubMed - indexed for MEDLINE]
7.

Beyond knockouts: cre resources for conditional mutagenesis.

Murray SA, Eppig JT, Smedley D, Simpson EM, Rosenthal N.

Mamm Genome. 2012 Oct;23(9-10):587-99. doi: 10.1007/s00335-012-9430-2. Epub 2012 Aug 29. Erratum in: Mamm Genome. 2012 Dec;23(11-12):791.

PMID:
22926223
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

PMID:
22458515
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Modelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencing.

Schmouth JF, Bonaguro RJ, Corso-Diaz X, Simpson EM.

PLoS Genet. 2012;8(3):e1002544. doi: 10.1371/journal.pgen.1002544. Epub 2012 Mar 1. Review.

PMID:
22396661
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice.

Schmouth JF, Banks KG, Mathelier A, Gregory-Evans CY, Castellarin M, Holt RA, Gregory-Evans K, Wasserman WW, Simpson EM.

Mol Cell Biol. 2012 Apr;32(7):1296-311. doi: 10.1128/MCB.06016-11. Epub 2012 Jan 30.

PMID:
22290436
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A rare cause of ear pain in a young boy.

Oliver AM, Simpson EM, Jerath RS.

J Pediatr. 2012 Feb;160(2):350. doi: 10.1016/j.jpeds.2011.08.030. Epub 2011 Oct 13. No abstract available.

PMID:
22000301
[PubMed - indexed for MEDLINE]
12.

A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro.

Aubrecht J, Goad ME, Czopik AK, Lerner CP, Johnson KA, Simpson EM, Schiestl RH.

Drug Chem Toxicol. 2011 Oct;34(4):433-9. doi: 10.3109/01480545.2010.544316. Epub 2011 Jul 11.

PMID:
21740348
[PubMed - indexed for MEDLINE]
13.

Kinematic and behavioral evidence for a distinction between trotting and ambling gaits in the cockroach Blaberus discoidalis.

Bender JA, Simpson EM, Tietz BR, Daltorio KA, Quinn RD, Ritzmann RE.

J Exp Biol. 2011 Jun 15;214(Pt 12):2057-64. doi: 10.1242/jeb.056481.

PMID:
21613522
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Computer-assisted 3D kinematic analysis of all leg joints in walking insects.

Bender JA, Simpson EM, Ritzmann RE.

PLoS One. 2010 Oct 26;5(10):e13617. doi: 10.1371/journal.pone.0013617.

PMID:
21049024
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A regulatory toolbox of MiniPromoters to drive selective expression in the brain.

Portales-Casamar E, Swanson DJ, Liu L, de Leeuw CN, Banks KG, Ho Sui SJ, Fulton DL, Ali J, Amirabbasi M, Arenillas DJ, Babyak N, Black SF, Bonaguro RJ, Brauer E, Candido TR, Castellarin M, Chen J, Chen Y, Cheng JC, Chopra V, Docking TR, Dreolini L, D'Souza CA, Flynn EK, Glenn R, Hatakka K, Hearty TG, Imanian B, Jiang S, Khorasan-zadeh S, Komljenovic I, Laprise S, Liao NY, Lim JS, Lithwick S, Liu F, Liu J, Lu M, McConechy M, McLeod AJ, Milisavljevic M, Mis J, O'Connor K, Palma B, Palmquist DL, Schmouth JF, Swanson MI, Tam B, Ticoll A, Turner JL, Varhol R, Vermeulen J, Watkins RF, Wilson G, Wong BK, Wong SH, Wong TY, Yang GS, Ypsilanti AR, Jones SJ, Holt RA, Goldowitz D, Wasserman WW, Simpson EM.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16589-94. doi: 10.1073/pnas.1009158107. Epub 2010 Aug 31.

PMID:
20807748
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1(frc/frc) mice.

Wong BK, Hossain SM, Trinh E, Ottmann GA, Budaghzadeh S, Zheng QY, Simpson EM.

Genes Brain Behav. 2010 Oct;9(7):681-94. doi: 10.1111/j.1601-183X.2010.00602.x. Epub 2010 Jun 21.

PMID:
20497236
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies.

Milisavljevic M, Hearty T, Wong TY, Portales-Casamar E, Simpson EM, Wasserman WW.

Mamm Genome. 2010 Jun;21(5-6):224-30. doi: 10.1007/s00335-010-9258-6. Epub 2010 Apr 22.

PMID:
20411264
[PubMed - indexed for MEDLINE]
18.

Expression analysis of novel striatal-enriched genes in Huntington disease.

Mazarei G, Neal SJ, Becanovic K, Luthi-Carter R, Simpson EM, Leavitt BR.

Hum Mol Genet. 2010 Feb 15;19(4):609-22. doi: 10.1093/hmg/ddp527. Epub 2009 Nov 23.

PMID:
19934114
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi.

Van Raamsdonk CD, Bezrookove V, Green G, Bauer J, Gaugler L, O'Brien JM, Simpson EM, Barsh GS, Bastian BC.

Nature. 2009 Jan 29;457(7229):599-602. doi: 10.1038/nature07586. Epub 2008 Dec 10.

PMID:
19078957
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Multicentric reticulohistiocytosis: diagnosis at the nailbeds.

Simpson EM, Goeckeritz BE, Teague DJ, Oliver AM.

J Rheumatol. 2008 Nov;35(11):2272-3. doi: 10.3899/jrheum.080423. No abstract available.

PMID:
19004054
[PubMed - indexed for MEDLINE]

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