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Results: 1 to 20 of 190


Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

Marcone S, Haughton K, Simpson PJ, Belton O, Fitzgerald DJ.

J Inflamm (Lond). 2015 Jan 20;12(1):1. doi: 10.1186/s12950-014-0044-1. eCollection 2015.


Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A.

Darby JF, Krysztofinska EM, Simpson PJ, Simon AC, Leznicki P, Sriskandarajah N, Bishop DS, Hale LR, Alfano C, Conte MR, Martínez-Lumbreras S, Thapaliya A, High S, Isaacson RL.

PLoS One. 2014 Nov 21;9(11):e113281. doi: 10.1371/journal.pone.0113281. eCollection 2014.


Surgical site infections (SSIs) after stoma reversal (SR): risk factors, implications, and protective strategies.

Chu DI, Schlieve CR, Colibaseanu DT, Simpson PJ, Wagie AE, Cima RR, Habermann EB.

J Gastrointest Surg. 2015 Feb;19(2):327-34. doi: 10.1007/s11605-014-2649-3. Epub 2014 Sep 13.


Aging impairs VEGF-mediated, androgen-dependent regulation of angiogenesis.

Lecce L, Lam YT, Lindsay LA, Yuen SC, Simpson PJ, Handelsman DJ, Ng MK.

Mol Endocrinol. 2014 Sep;28(9):1487-501. doi: 10.1210/me.2013-1405. Epub 2014 Jul 24.


Surgical outcomes in adults with benign and malignant sacrococcygeal teratoma: a single-institution experience of 26 cases.

Simpson PJ, Wise KB, Merchea A, Cheville JC, Moir C, Larson DW, Dozois EJ.

Dis Colon Rectum. 2014 Jul;57(7):851-7. doi: 10.1097/DCR.0000000000000117.


The relationship between endothelial progenitor cell populations and epicardial and microvascular coronary disease-a cellular, angiographic and physiologic study.

Chan KH, Simpson PJ, Yong AS, Dunn LL, Chawantanpipat C, Hsu C, Yu Y, Keech AC, Celermajer DS, Ng MK.

PLoS One. 2014 Apr 15;9(4):e93980. doi: 10.1371/journal.pone.0093980. eCollection 2014.


Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital.

Hotham JE, Simpson PJ, Brooman-White RS, Basu A, Ross CC, Humphreys SA, Larkin F, Gupta N, Das M.

CNS Spectr. 2014 Oct;19(5):403-10. doi: 10.1017/S1092852913000874. Epub 2013 Nov 28.


A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis.

Dunn LL, Simpson PJ, Prosser HC, Lecce L, Yuen GS, Buckle A, Sieveking DP, Vanags LZ, Lim PR, Chow RW, Lam YT, Clayton Z, Bao S, Davies MJ, Stadler N, Celermajer DS, Stocker R, Bursill CA, Cooke JP, Ng MK.

Diabetes. 2014 Feb;63(2):675-87. doi: 10.2337/db13-0417. Epub 2013 Nov 5.


Heterogenous malignant presacral teratoma with a locally destructive benign intrasacral component.

Simpson PJ, Kehl J, Rose PS, Dozois EJ.

Tech Coloproctol. 2014 Jun;18(6):605-6. doi: 10.1007/s10151-013-1087-7. Epub 2013 Nov 1. No abstract available.


The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase.

Tabib-Salazar A, Liu B, Doughty P, Lewis RA, Ghosh S, Parsy ML, Simpson PJ, O'Dwyer K, Matthews SJ, Paget MS.

Nucleic Acids Res. 2013 Jun;41(11):5679-91. doi: 10.1093/nar/gkt277. Epub 2013 Apr 19.


Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteins.

Leen EN, Kwok KY, Birtley JR, Simpson PJ, Subba-Reddy CV, Chaudhry Y, Sosnovtsev SV, Green KY, Prater SN, Tong M, Young JC, Chung LM, Marchant J, Roberts LO, Kao CC, Matthews S, Goodfellow IG, Curry S.

J Virol. 2013 May;87(10):5318-30. doi: 10.1128/JVI.03151-12. Epub 2013 Mar 13.


Effects of continuous positive airway pressure on endothelial function and circulating progenitor cells in obstructive sleep apnoea: a randomised sham-controlled study.

Simpson PJ, Hoyos CM, Celermajer D, Liu PY, Ng MK.

Int J Cardiol. 2013 Oct 3;168(3):2042-8. doi: 10.1016/j.ijcard.2013.01.166. Epub 2013 Feb 27.


Specific DNA recognition mediated by a type IV pilin.

Cehovin A, Simpson PJ, McDowell MA, Brown DR, Noschese R, Pallett M, Brady J, Baldwin GS, Lea SM, Matthews SJ, Pelicic V.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3065-70. doi: 10.1073/pnas.1218832110. Epub 2013 Feb 5.


Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteins.

Simon AC, Simpson PJ, Goldstone RM, Krysztofinska EM, Murray JW, High S, Isaacson RL.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1327-32. doi: 10.1073/pnas.1207518110. Epub 2013 Jan 7.


Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia.

Hilcenko C, Simpson PJ, Finch AJ, Bowler FR, Churcher MJ, Jin L, Packman LC, Shlien A, Campbell P, Kirwan M, Dokal I, Warren AJ.

Blood. 2013 Feb 7;121(6):1028-38. doi: 10.1182/blood-2012-10-461491. Epub 2012 Nov 27.


1H, 13C and 15N assignments of Sgt2 N-terminal dimerisation domain and its binding partner, Get5 Ubiquitin-like domain.

Simon AC, Simpson PJ, Hawthorne W, Hale LR, Goldstone RM, Isaacson RL.

Biomol NMR Assign. 2013 Oct;7(2):271-4. doi: 10.1007/s12104-012-9425-7. Epub 2012 Sep 22.


Regulation of the Plasmodium motor complex: phosphorylation of myosin A tail-interacting protein (MTIP) loosens its grip on MyoA.

Douse CH, Green JL, Salgado PS, Simpson PJ, Thomas JC, Langsley G, Holder AA, Tate EW, Cota E.

J Biol Chem. 2012 Oct 26;287(44):36968-77. doi: 10.1074/jbc.M112.379842. Epub 2012 Aug 29.


Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state.

Jollis JG, Al-Khalidi HR, Monk L, Roettig ML, Garvey JL, Aluko AO, Wilson BH, Applegate RJ, Mears G, Corbett CC, Granger CB; Regional Approach to Cardiovascular Emergencies (RACE) Investigators.

Circulation. 2012 Jul 10;126(2):189-95. doi: 10.1161/CIRCULATIONAHA.111.068049. Epub 2012 Jun 4.


Changes in protein dynamics of the DNA repair dioxygenase AlkB upon binding of Fe(2+) and 2-oxoglutarate.

Bleijlevens B, Shivarattan T, van den Boom KS, de Haan A, van der Zwan G, Simpson PJ, Matthews SJ.

Biochemistry. 2012 Apr 24;51(16):3334-41. doi: 10.1021/bi201699e. Epub 2012 Apr 9.


Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus.

Garnett JA, Martínez-Santos VI, Saldaña Z, Pape T, Hawthorne W, Chan J, Simpson PJ, Cota E, Puente JL, Girón JA, Matthews S.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3950-5. doi: 10.1073/pnas.1106733109. Epub 2012 Feb 21.

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