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Results: 1 to 20 of 33

1.

Genomic landscape of rat strain and substrain variation.

Hermsen R, de Ligt J, Spee W, Blokzijl F, Schäfer S, Adami E, Boymans S, Flink S, van Boxtel R, van der Weide RH, Aitman T, Hübner N, Simonis M, Tabakoff B, Guryev V, Cuppen E.

BMC Genomics. 2015 May 6;16:357. doi: 10.1186/s12864-015-1594-1.

2.

Lack of major genome instability in tumors of p53 null rats.

Hermsen R, Toonen P, Kuijk E, Youssef SA, Kuiper R, van Heesch S, de Bruin A, Cuppen E, Simonis M.

PLoS One. 2015 Mar 26;10(3):e0122066. doi: 10.1371/journal.pone.0122066. eCollection 2015.

3.

Instant live-cell super-resolution imaging of cellular structures by nanoinjection of fluorescent probes.

Hennig S, van de Linde S, Lummer M, Simonis M, Huser T, Sauer M.

Nano Lett. 2015 Feb 11;15(2):1374-81. doi: 10.1021/nl504660t. Epub 2015 Jan 6.

PMID:
25533766
4.

Genomic and functional overlap between somatic and germline chromosomal rearrangements.

van Heesch S, Simonis M, van Roosmalen MJ, Pillalamarri V, Brand H, Kuijk EW, de Luca KL, Lansu N, Braat AK, Menelaou A, Hao W, Korving J, Snijder S, van der Veken LT, Hochstenbach R, Knegt AC, Duran K, Renkens I, Alekozai N, Jager M, Vergult S, Menten B, de Bruijn E, Boymans S, Ippel E, van Binsbergen E, Talkowski ME, Lichtenbelt K, Cuppen E, Kloosterman WP.

Cell Rep. 2014 Dec 24;9(6):2001-10. doi: 10.1016/j.celrep.2014.11.022. Epub 2014 Dec 11.

5.

Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes.

van Heesch S, van Iterson M, Jacobi J, Boymans S, Essers PB, de Bruijn E, Hao W, MacInnes AW, Cuppen E, Simonis M.

Genome Biol. 2014 Jan 7;15(1):R6. doi: 10.1186/gb-2014-15-1-r6.

6.

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells.

Holwerda SJ, van de Werken HJ, Ribeiro de Almeida C, Bergen IM, de Bruijn MJ, Verstegen MJ, Simonis M, Splinter E, Wijchers PJ, Hendriks RW, de Laat W.

Nucleic Acids Res. 2013 Aug;41(14):6905-16. doi: 10.1093/nar/gkt491. Epub 2013 Jun 7.

7.

Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain.

van Nuland R, van Schaik FM, Simonis M, van Heesch S, Cuppen E, Boelens R, Timmers HM, van Ingen H.

Epigenetics Chromatin. 2013 May 8;6(1):12. doi: 10.1186/1756-8935-6-12.

8.

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

Simonis M, Atanur SS, Linsen S, Guryev V, Ruzius FP, Game L, Lansu N, de Bruijn E, van Heesch S, Jones SJ, Pravenec M, Aitman TJ, Cuppen E.

Genome Biol. 2012 Apr 27;13(4):r31. doi: 10.1186/gb-2012-13-4-r31.

9.

Variegated gene expression caused by cell-specific long-range DNA interactions.

Noordermeer D, de Wit E, Klous P, van de Werken H, Simonis M, Lopez-Jones M, Eussen B, de Klein A, Singer RH, de Laat W.

Nat Cell Biol. 2011 Jun 26;13(8):944-51. doi: 10.1038/ncb2278.

10.

Interactions among Polycomb domains are guided by chromosome architecture.

Tolhuis B, Blom M, Kerkhoven RM, Pagie L, Teunissen H, Nieuwland M, Simonis M, de Laat W, van Lohuizen M, van Steensel B.

PLoS Genet. 2011 Mar;7(3):e1001343. doi: 10.1371/journal.pgen.1001343. Epub 2011 Mar 24.

11.

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology.

Simonis M, Klous P, Homminga I, Galjaard RJ, Rijkers EJ, Grosveld F, Meijerink JP, de Laat W.

Nat Methods. 2009 Nov;6(11):837-42. doi: 10.1038/nmeth.1391. Epub 2009 Oct 11.

PMID:
19820713
12.

FISH-eyed and genome-wide views on the spatial organisation of gene expression.

Simonis M, de Laat W.

Biochim Biophys Acta. 2008 Nov;1783(11):2052-60. doi: 10.1016/j.bbamcr.2008.07.020. Epub 2008 Aug 5. Review.

13.

Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription.

Palstra RJ, Simonis M, Klous P, Brasset E, Eijkelkamp B, de Laat W.

PLoS One. 2008 Feb 20;3(2):e1661. doi: 10.1371/journal.pone.0001661.

14.

Three-dimensional organization of gene expression in erythroid cells.

de Laat W, Klous P, Kooren J, Noordermeer D, Palstra RJ, Simonis M, Splinter E, Grosveld F.

Curr Top Dev Biol. 2008;82:117-39. doi: 10.1016/S0070-2153(07)00005-1. Review.

PMID:
18282519
15.

An evaluation of 3C-based methods to capture DNA interactions.

Simonis M, Kooren J, de Laat W.

Nat Methods. 2007 Nov;4(11):895-901. Review.

PMID:
17971780
16.

Oncogenic pathways impinging on the G2-restriction point.

Foijer F, Simonis M, van Vliet M, Wessels L, Kerkhoven R, Sorger PK, Te Riele H.

Oncogene. 2008 Feb 14;27(8):1142-54. Epub 2007 Aug 13.

PMID:
17700522
17.

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

Simonis M, Klous P, Splinter E, Moshkin Y, Willemsen R, de Wit E, van Steensel B, de Laat W.

Nat Genet. 2006 Nov;38(11):1348-54. Epub 2006 Oct 8.

PMID:
17033623
18.

The metabolism of linoleic acid in healthy subjects after intake of a single dose of (13)C-linoleic acid.

Vermunt SH, Mensink RP, Simonis MM, Wagenmakers AJ, Hornstra G.

Eur J Clin Nutr. 2001 May;55(5):321-6.

19.

Effects of dietary alpha-linolenic acid on the conversion and oxidation of 13C-alpha-linolenic acid.

Vermunt SH, Mensink RP, Simonis MM, Hornstra G.

Lipids. 2000 Feb;35(2):137-42.

PMID:
10757543
20.

Effects of point mutations in the readthrough domain of the beet western yellows virus minor capsid protein on virus accumulation in planta and on transmission by aphids.

Brault V, Mutterer J, Scheidecker D, Simonis MT, Herrbach E, Richards K, Ziegler-Graff V.

J Virol. 2000 Feb;74(3):1140-8.

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