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Altered trafficking of abnormal prion protein in atypical scrapie: Prion protein accumulation in oligodendroglial inner mesaxons.

Jeffrey M, González L, Simmons MM, Hunter N, Martin S, McGovern G.

Neuropathol Appl Neurobiol. 2016 Jan 10. doi: 10.1111/nan.12302. [Epub ahead of print]


Firearm Prevalence and Homicides of Law Enforcement Officers in the United States.

Swedler DI, Simmons MM, Dominici F, Hemenway D.

Am J Public Health. 2015 Oct;105(10):2042-8. doi: 10.2105/AJPH.2015.302749. Epub 2015 Aug 13.


Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?

Simmons MM, Chaplin MJ, Vickery CM, Simon S, Davis L, Denyer M, Lockey R, Stack MJ, O'Connor MJ, Bishop K, Gough KC, Maddison BC, Thorne L, Spiropoulos J.

J Clin Microbiol. 2015 Aug;53(8):2593-604. doi: 10.1128/JCM.00508-15. Epub 2015 Jun 3.


Ability of wild type mouse bioassay to detect bovine spongiform encephalopathy (BSE) in the presence of excess scrapie.

Corda E, Thorne L, Beck KE, Lockey R, Green RB, Vickery CM, Holder TM, Terry LA, Simmons MM, Spiropoulos J.

Acta Neuropathol Commun. 2015 Apr 3;3:21. doi: 10.1186/s40478-015-0194-2.


Phenotype shift from atypical scrapie to CH1641 following experimental transmission in sheep.

Simmons MM, Moore SJ, Lockey R, Chaplin MJ, Konold T, Vickery C, Spiropoulos J.

PLoS One. 2015 Feb 24;10(2):e0117063. doi: 10.1371/journal.pone.0117063. eCollection 2015.


The pathological and molecular but not clinical phenotypes are maintained after second passage of experimental atypical bovine spongiform encephalopathy in cattle.

Konold T, Phelan LJ, Clifford D, Chaplin MJ, Cawthraw S, Stack MJ, Simmons MM.

BMC Vet Res. 2014 Oct 2;10:243. doi: 10.1186/s12917-014-0243-2.


Allelic variants at codon 146 in the PRNP gene show significant differences in the risk for natural scrapie in Cypriot goats.

Ortiz-Pelaez A, Georgiadou S, Simmons MM, Windl O, Dawson M, Arnold ME, Neocleous P, Papasavva-Stylianou P.

Epidemiol Infect. 2015 Apr;143(6):1304-10. doi: 10.1017/S0950268814002064. Epub 2014 Aug 20.


Evidence of in utero transmission of classical scrapie in sheep.

Spiropoulos J, Hawkins SA, Simmons MM, Bellworthy SJ.

J Virol. 2014 Apr;88(8):4591-4. doi: 10.1128/JVI.03264-13. Epub 2014 Jan 22.


Assessing the susceptibility of transgenic mice overexpressing deer prion protein to bovine spongiform encephalopathy.

Vickery CM, Lockey R, Holder TM, Thorne L, Beck KE, Wilson C, Denyer M, Sheehan J, Marsh S, Webb PR, Dexter I, Norman A, Popescu E, Schneider A, Holden P, Griffiths PC, Plater JM, Dagleish MP, Martin S, Telling GC, Simmons MM, Spiropoulos J.

J Virol. 2014 Feb;88(3):1830-3. doi: 10.1128/JVI.02762-13. Epub 2013 Nov 20.


Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.

Wadsworth JD, Joiner S, Linehan JM, Balkema-Buschmann A, Spiropoulos J, Simmons MM, Griffiths PC, Groschup MH, Hope J, Brandner S, Asante EA, Collinge J.

Emerg Infect Dis. 2013 Nov;19(11):1731-9. doi: 10.3201/eid1911.121341.


Disease characteristics of bovine spongiform encephalopathy following inoculation into mice via three different routes.

Vickery CM, Beck KE, Simmons MM, Hawkins SA, Spiropoulos J.

Int J Exp Pathol. 2013 Oct;94(5):320-8. doi: 10.1111/iep.12036.


Occupational homicide of law enforcement officers in the US, 1996-2010.

Swedler DI, Kercher C, Simmons MM, Pollack KM.

Inj Prev. 2014 Feb;20(1):35-40. doi: 10.1136/injuryprev-2013-040799. Epub 2013 May 31.


Evidence of effective scrapie transmission via colostrum and milk in sheep.

Konold T, Moore SJ, Bellworthy SJ, Terry LA, Thorne L, Ramsay A, Salguero FJ, Simmons MM, Simmons HA.

BMC Vet Res. 2013 May 7;9:99. doi: 10.1186/1746-6148-9-99.


Four BSE cases with an L-BSE molecular profile in cattle from Great Britain.

Stack MJ, Chaplin MJ, Davis LA, Everitt S, Simmons MM, Windl O, Hope J, Burke P.

Vet Rec. 2013 Jan 19;172(3):70. doi: 10.1136/vr.101158. Epub 2012 Dec 18.


The interpretation of disease phenotypes to identify TSE strains in mice: characterisation of BSE using PrPSc distribution patterns in the brain.

Corda E, Beck KE, Sallis RE, Vickery CM, Denyer M, Webb PR, Bellworthy SJ, Spencer YI, Simmons MM, Spiropoulos J.

Vet Res. 2012 Dec 17;43:86. doi: 10.1186/1297-9716-43-86.


Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle - an update.

Konold T, Arnold ME, Austin AR, Cawthraw S, Hawkins SA, Stack MJ, Simmons MM, Sayers AR, Dawson M, Wilesmith JW, Wells GA.

BMC Res Notes. 2012 Dec 5;5:674. doi: 10.1186/1756-0500-5-674.


The interpretation of disease phenotypes to identify TSE strains following murine bioassay: characterisation of classical scrapie.

Beck KE, Vickery CM, Lockey R, Holder T, Thorne L, Terry LA, Denyer M, Webb P, Simmons MM, Spiropoulos J.

Vet Res. 2012 Nov 1;43:77. doi: 10.1186/1297-9716-43-77.


Minimal involvement of the circumventricular organs in the pathogenesis of spontaneously arising and experimentally induced classical bovine spongiform encephalopathy.

Sisó S, Martin S, Konold T, Hawkins SA, Thurston L, Simmons MM, Stack MJ, Jeffrey M, González L.

J Comp Pathol. 2012 Aug-Oct;147(2-3):305-15. doi: 10.1016/j.jcpa.2012.01.008. Epub 2012 Apr 18.


Ultrastructural findings in pigs experimentally infected with bovine spongiform encephalopathy agent.

Liberski PP, Sikorska B, Wells GA, Hawkins SA, Dawson M, Simmons MM.

Folia Neuropathol. 2012;50(1):89-98.


Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges.

Konold T, Bone GE, Clifford D, Chaplin MJ, Cawthraw S, Stack MJ, Simmons MM.

BMC Vet Res. 2012 Mar 8;8:22. doi: 10.1186/1746-6148-8-22.

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