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Results: 1 to 20 of 37


Shifting sugars and shifting paradigms.

Siegal ML.

PLoS Biol. 2015 Feb 17;13(2):e1002068. doi: 10.1371/journal.pbio.1002068. eCollection 2015 Feb.


Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness.

Bauer CR, Li S, Siegal ML.

Mol Syst Biol. 2015 Jan 21;11(1):773. doi: 10.15252/msb.20145264.


Reply to Chen and Zhang: On interpreting genome-wide trends from yeast mutation accumulation data.

Zhu YO, Siegal ML, Hall DW, Petrov DA.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4063. doi: 10.1073/pnas.1413861111. Epub 2014 Sep 12. No abstract available.


The genetics of sex: exploring differences.

Arbeitman MN, Kopp A, Siegal ML, Van Doren M.

G3 (Bethesda). 2014 Jun 17;4(6):979-81. doi: 10.1534/g3.114.011692.


Precise estimates of mutation rate and spectrum in yeast.

Zhu YO, Siegal ML, Hall DW, Petrov DA.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2310-8. doi: 10.1073/pnas.1323011111. Epub 2014 May 20.


Testing the key assumption of heritability estimates based on genome-wide genetic relatedness.

Conley D, Siegal ML, Domingue BW, Mullan Harris K, McQueen MB, Boardman JD.

J Hum Genet. 2014 Jun;59(6):342-5. doi: 10.1038/jhg.2014.14. Epub 2014 Mar 6.


Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations.

Richardson JB, Uppendahl LD, Traficante MK, Levy SF, Siegal ML.

PLoS Genet. 2013;9(8):e1003733. doi: 10.1371/journal.pgen.1003733. Epub 2013 Aug 22.


Genetic and nongenetic determinants of cell growth variation assessed by high-throughput microscopy.

Ziv N, Siegal ML, Gresham D.

Mol Biol Evol. 2013 Dec;30(12):2568-78. doi: 10.1093/molbev/mst138. Epub 2013 Aug 11.


Heritability and the equal environments assumption: evidence from multiple samples of misclassified twins.

Conley D, Rauscher E, Dawes C, Magnusson PK, Siegal ML.

Behav Genet. 2013 Sep;43(5):415-26. doi: 10.1007/s10519-013-9602-1. Epub 2013 Aug 1.


Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection.

Conley D, Rauscher E, Siegal ML.

Biodemography Soc Biol. 2013;59(1):37-56. doi: 10.1080/19485565.2013.774620.


The details in the distributions: why and how to study phenotypic variability.

Geiler-Samerotte KA, Bauer CR, Li S, Ziv N, Gresham D, Siegal ML.

Curr Opin Biotechnol. 2013 Aug;24(4):752-9. doi: 10.1016/j.copbio.2013.03.010. Epub 2013 Apr 6.


Crouching variation revealed.

Siegal ML.

Mol Ecol. 2013 Mar;22(5):1187-9. doi: 10.1111/mec.12195.


Oh, the places they'll go: Female sperm storage and sperm precedence in Drosophila melanogaster.

Schnakenberg SL, Siegal ML, Bloch Qazi MC.

Spermatogenesis. 2012 Jul 1;2(3):224-235.


The robustness continuum.

Levy SF, Siegal ML.

Adv Exp Med Biol. 2012;751:431-52. doi: 10.1007/978-1-4614-3567-9_20.


Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity.

Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H.

Genome Res. 2012 Oct;22(10):1930-9. doi: 10.1101/gr.134080.111. Epub 2012 May 29.


Pausing on the path to robustness.

Siegal ML, Rushlow C.

Dev Cell. 2012 May 15;22(5):905-6. doi: 10.1016/j.devcel.2012.04.020.


Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant.

Levy SF, Ziv N, Siegal ML.

PLoS Biol. 2012;10(5):e1001325. doi: 10.1371/journal.pbio.1001325. Epub 2012 May 8.


Hsp90 depletion goes wild.

Siegal ML, Masel J.

BMC Biol. 2012 Feb 27;10:14. doi: 10.1186/1741-7007-10-14.


Sperm-storage defects and live birth in Drosophila females lacking spermathecal secretory cells.

Schnakenberg SL, Matias WR, Siegal ML.

PLoS Biol. 2011 Nov;9(11):e1001192. doi: 10.1371/journal.pbio.1001192. Epub 2011 Nov 8.


The female-specific doublesex isoform regulates pleiotropic transcription factors to pattern genital development in Drosophila.

Chatterjee SS, Uppendahl LD, Chowdhury MA, Ip PL, Siegal ML.

Development. 2011 Mar;138(6):1099-109. doi: 10.1242/dev.055731.

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