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Items: 16


C646, a Novel p300/CREB-Binding Protein-Specific Inhibitor of Histone Acetyltransferase, Attenuates Influenza A Virus Infection.

Zhao D, Fukuyama S, Sakai-Tagawa Y, Takashita E, Shoemaker JE, Kawaoka Y.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1902-6. doi: 10.1128/AAC.02055-15.


Identifying problematic drugs based on the characteristics of their targets.

Lopes TJ, Shoemaker JE, Matsuoka Y, Kawaoka Y, Kitano H.

Front Pharmacol. 2015 Sep 1;6:186. doi: 10.3389/fphar.2015.00186. eCollection 2015.


An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation.

Shoemaker JE, Fukuyama S, Eisfeld AJ, Zhao D, Kawakami E, Sakabe S, Maemura T, Gorai T, Katsura H, Muramoto Y, Watanabe S, Watanabe T, Fuji K, Matsuoka Y, Kitano H, Kawaoka Y.

PLoS Pathog. 2015 Jun 5;11(6):e1004856. doi: 10.1371/journal.ppat.1004856. eCollection 2015 Jun.


Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies.

Fukuyama S, Katsura H, Zhao D, Ozawa M, Ando T, Shoemaker JE, Ishikawa I, Yamada S, Neumann G, Watanabe S, Kitano H, Kawaoka Y.

Nat Commun. 2015 Mar 25;6:6600. doi: 10.1038/ncomms7600.


Influenza virus-host interactome screen as a platform for antiviral drug development.

Watanabe T, Kawakami E, Shoemaker JE, Lopes TJ, Matsuoka Y, Tomita Y, Kozuka-Hata H, Gorai T, Kuwahara T, Takeda E, Nagata A, Takano R, Kiso M, Yamashita M, Sakai-Tagawa Y, Katsura H, Nonaka N, Fujii H, Fujii K, Sugita Y, Noda T, Goto H, Fukuyama S, Watanabe S, Neumann G, Oyama M, Kitano H, Kawaoka Y.

Cell Host Microbe. 2014 Dec 10;16(6):795-805. doi: 10.1016/j.chom.2014.11.002. Epub 2014 Nov 20.


Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses.

Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y.

J Virol. 2014 Aug;88(16):8981-97. doi: 10.1128/JVI.00907-14. Epub 2014 Jun 4.


A comprehensive map of the influenza A virus replication cycle.

Matsuoka Y, Matsumae H, Katoh M, Eisfeld AJ, Neumann G, Hase T, Ghosh S, Shoemaker JE, Lopes TJ, Watanabe T, Watanabe S, Fukuyama S, Kitano H, Kawaoka Y.

BMC Syst Biol. 2013 Oct 2;7:97. doi: 10.1186/1752-0509-7-97.


Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.

Schaefer MH, Lopes TJ, Mah N, Shoemaker JE, Matsuoka Y, Fontaine JF, Louis-Jeune C, Eisfeld AJ, Neumann G, Perez-Iratxeta C, Kawaoka Y, Kitano H, Andrade-Navarro MA.

PLoS Comput Biol. 2013;9(1):e1002860. doi: 10.1371/journal.pcbi.1002860. Epub 2013 Jan 3.


CTen: a web-based platform for identifying enriched cell types from heterogeneous microarray data.

Shoemaker JE, Lopes TJ, Ghosh S, Matsuoka Y, Kawaoka Y, Kitano H.

BMC Genomics. 2012 Sep 6;13:460. doi: 10.1186/1471-2164-13-460.


Integrated network analysis reveals a novel role for the cell cycle in 2009 pandemic influenza virus-induced inflammation in macaque lungs.

Shoemaker JE, Fukuyama S, Eisfeld AJ, Muramoto Y, Watanabe S, Watanabe T, Matsuoka Y, Kitano H, Kawaoka Y.

BMC Syst Biol. 2012 Aug 31;6:117. doi: 10.1186/1752-0509-6-117.


Confidence from uncertainty--a multi-target drug screening method from robust control theory.

Luni C, Shoemaker JE, Sanft KR, Petzold LR, Doyle FJ 3rd.

BMC Syst Biol. 2010 Nov 24;4:161. doi: 10.1186/1752-0509-4-161.


Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk.

Shoemaker JE, Gayen K, Garcia-Reyero N, Perkins EJ, Villeneuve DL, Liu L, Doyle FJ 3rd.

BMC Syst Biol. 2010 Jun 28;4:89. doi: 10.1186/1752-0509-4-89.


Identifying fragilities in biochemical networks: robust performance analysis of Fas signaling-induced apoptosis.

Shoemaker JE, Doyle FJ 3rd.

Biophys J. 2008 Sep 15;95(6):2610-23. doi: 10.1529/biophysj.107.123398. Epub 2008 Jun 6.


Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.

Bennett CF, Chiang MY, Chan H, Shoemaker JE, Mirabelli CK.

Mol Pharmacol. 1992 Jun;41(6):1023-33.


The effects of muscle relaxation on blood pressure of essential hypertensives.

Shoemaker JE, Tasto DL.

Behav Res Ther. 1975 Feb;13(1):29-43. No abstract available.

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