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Results: 19

1.

Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease.

Carman AJ, Dacks PA, Lane RF, Shineman DW, Fillit HM.

J Nutr Health Aging. 2014 Apr;18(4):383-92. doi: 10.1007/s12603-014-0021-7.

PMID:
24676319
[PubMed - in process]
2.

Developing novel blood-based biomarkers for Alzheimer's disease.

Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, Bain LJ, Shineman DW, Weiner M, Fillit HM.

Alzheimers Dement. 2014 Jan;10(1):109-14. doi: 10.1016/j.jalz.2013.10.007.

PMID:
24365657
[PubMed - in process]
3.

Progress in novel cognitive enhancers for cognitive aging and Alzheimer's disease.

Shineman DW, Carman AJ, Dacks PA, Lane RF, Fillit HM.

Alzheimers Res Ther. 2013 Oct 2;5(5):45. doi: 10.1186/alzrt209. eCollection 2013.

PMID:
24083622
[PubMed]
Free PMC Article
4.

Optimizing the use of CROs by academia and small companies.

Lane RF, Friedman LG, Keith C, Braithwaite SP, Frearson JA, Lowe DA, Longo FM, Refolo LM, Watterson DM, Tsaioun K, Shineman DW, Fillit HM.

Nat Rev Drug Discov. 2013 Jul;12(7):487-8. doi: 10.1038/nrd4057. No abstract available.

PMID:
23812255
[PubMed - indexed for MEDLINE]
5.

Current evidence for the clinical use of long-chain polyunsaturated n-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease.

Dacks PA, Shineman DW, Fillit HM.

J Nutr Health Aging. 2013 Mar;17(3):240-51. doi: 10.1007/s12603-012-0431-3.

PMID:
23459977
[PubMed - indexed for MEDLINE]
6.
7.

Beyond amyloid: the future of therapeutics for Alzheimer's disease.

Lane RF, Shineman DW, Steele JW, Lee LB, Fillit HM.

Adv Pharmacol. 2012;64:213-71. doi: 10.1016/B978-0-12-394816-8.00007-6. Review.

PMID:
22840749
[PubMed - indexed for MEDLINE]
8.

Beyond amyloid: a diverse portfolio of novel drug discovery programs for Alzheimer's disease and related dementias.

Lane RF, Shineman DW, Fillit HM.

Alzheimers Res Ther. 2011 Dec 15;3(6):36. doi: 10.1186/alzrt99.

PMID:
22236739
[PubMed]
Free PMC Article
9.

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies.

Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, Sweeney P, Yrjänheikki J, Fillit HM.

Alzheimers Res Ther. 2011 Sep 28;3(5):28. doi: 10.1186/alzrt90.

PMID:
21943025
[PubMed]
Free PMC Article
10.

An analysis of global research funding for the frontotemporal dementias: 1998-2008.

Walentas CD, Shineman DW, Horton AR, Boeve BF, Fillit HM.

Alzheimers Dement. 2011 Mar;7(2):142-50. doi: 10.1016/j.jalz.2010.11.010. Epub 2011 Jan 26.

PMID:
21276758
[PubMed - indexed for MEDLINE]
12.

Therapeutics for cognitive aging.

Shineman DW, Salthouse TA, Launer LJ, Hof PR, Bartzokis G, Kleiman R, Luine V, Buccafusco JJ, Small GW, Aisen PS, Lowe DA, Fillit HM.

Ann N Y Acad Sci. 2010 Apr;1191 Suppl 1:E1-15. doi: 10.1111/j.1749-6632.2010.05532.x.

PMID:
20392284
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Alzheimer's disease drug discovery: Abeta and beyond.

Shineman DW, Fillit HM.

Curr Alzheimer Res. 2010 May;7(3):188-9. No abstract available.

PMID:
20406195
[PubMed - indexed for MEDLINE]
14.

A multi-targeted approach for a complex multifaceted disease.

Shineman DW, Fillit HM.

Curr Alzheimer Res. 2009 Oct;6(5):407-8. No abstract available.

PMID:
19860641
[PubMed - indexed for MEDLINE]
15.

Novel strategies for the prevention of dementia from Alzheimer's disease.

Shineman DW, Fillit HM.

Dialogues Clin Neurosci. 2009;11(2):129-34. Review.

PMID:
19585948
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Meeting the unique challenges of drug discovery for neurodegenerative diseases.

Shineman DW, Fillit HM.

BMC Neurol. 2009 Jun 12;9 Suppl 1:I1. doi: 10.1186/1471-2377-9-S1-I1. No abstract available.

PMID:
19534729
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Constitutively active Akt inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase.

Shineman DW, Dain AS, Kim ML, Lee VM.

Biochemistry. 2009 May 5;48(17):3787-94. doi: 10.1021/bi802070j.

PMID:
19236051
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice.

Shineman DW, Zhang B, Leight SN, Pratico D, Lee VM.

J Neurosci. 2008 Apr 30;28(18):4785-94. doi: 10.1523/JNEUROSCI.0684-08.2008.

PMID:
18448655
[PubMed - indexed for MEDLINE]
Free Article
19.

Role for Akt3/protein kinase Bgamma in attainment of normal brain size.

Easton RM, Cho H, Roovers K, Shineman DW, Mizrahi M, Forman MS, Lee VM, Szabolcs M, de Jong R, Oltersdorf T, Ludwig T, Efstratiadis A, Birnbaum MJ.

Mol Cell Biol. 2005 Mar;25(5):1869-78.

PMID:
15713641
[PubMed - indexed for MEDLINE]
Free PMC Article

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