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Results: 1 to 20 of 49

1.

The HIP2~Ubiquitin Conjugate Forms a Non-Compact Monomeric Thioester during Di-Ubiquitin Synthesis.

Cook BW, Barber KR, Shilton BH, Shaw GS.

PLoS One. 2015 Mar 23;10(3):e0120318. doi: 10.1371/journal.pone.0120318. eCollection 2015.

2.

Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape.

Litchfield DW, Shilton BH, Brandl CJ, Gyenis L.

Biochim Biophys Acta. 2015 Mar 10. pii: S0304-4165(15)00081-1. doi: 10.1016/j.bbagen.2015.02.018. [Epub ahead of print] Review.

PMID:
25766872
3.

Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1.

Innes BT, Sowole MA, Gyenis L, Dubinsky M, Konermann L, Litchfield DW, Brandl CJ, Shilton BH.

Biochim Biophys Acta. 2015 May;1852(5):905-12. doi: 10.1016/j.bbadis.2014.12.025. Epub 2015 Jan 13.

4.

Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT.

Leung KK, Shilton BH.

Biochemistry. 2015 Jan 13;54(1):47-59. doi: 10.1021/bi500959t. Epub 2014 Nov 18.

PMID:
25379648
5.

Crystal and solution structure analysis of FhuD2 from Staphylococcus aureus in multiple unliganded conformations and bound to ferrioxamine-B.

Podkowa KJ, Briere LA, Heinrichs DE, Shilton BH.

Biochemistry. 2014 Apr 1;53(12):2017-31. doi: 10.1021/bi401349d. Epub 2014 Mar 19.

PMID:
24606332
6.

The PS1 hairpin of Mcm3 is essential for viability and for DNA unwinding in vitro.

Lam SK, Ma X, Sing TL, Shilton BH, Brandl CJ, Davey MJ.

PLoS One. 2013 Dec 11;8(12):e82177. doi: 10.1371/journal.pone.0082177. eCollection 2013.

7.

Chloroquine binding reveals flavin redox switch function of quinone reductase 2.

Leung KK, Shilton BH.

J Biol Chem. 2013 Apr 19;288(16):11242-51. doi: 10.1074/jbc.M113.457002. Epub 2013 Mar 7.

8.

Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding.

Innes BT, Bailey ML, Brandl CJ, Shilton BH, Litchfield DW.

Front Physiol. 2013 Feb 13;4:18. doi: 10.3389/fphys.2013.00018. eCollection 2013.

9.
10.

Flavin adenine dinucleotide content of quinone reductase 2: analysis and optimization for structure-function studies.

Leung KK, Litchfield DW, Shilton BH.

Anal Biochem. 2012 Jan 1;420(1):84-9. doi: 10.1016/j.ab.2011.09.011. Epub 2011 Sep 16.

PMID:
21971443
11.

Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.

Duncan KE, Dempsey BR, Killip LE, Adams J, Bailey ML, Lajoie GA, Litchfield DW, Brandl CJ, Shaw GS, Shilton BH.

J Med Chem. 2011 Jun 9;54(11):3854-65. doi: 10.1021/jm200156c. Epub 2011 May 5.

PMID:
21545152
12.

Synthetic triterpenoids target the Arp2/3 complex and inhibit branched actin polymerization.

To C, Shilton BH, Di Guglielmo GM.

J Biol Chem. 2010 Sep 3;285(36):27944-57. doi: 10.1074/jbc.M110.103036. Epub 2010 Jun 21.

13.

Studies of the maltose transport system reveal a mechanism for coupling ATP hydrolysis to substrate translocation without direct recognition of substrate.

Gould AD, Shilton BH.

J Biol Chem. 2010 Apr 9;285(15):11290-6. doi: 10.1074/jbc.M109.089078. Epub 2010 Feb 10.

14.

Site-specific IGFBP-1 hyper-phosphorylation in fetal growth restriction: clinical and functional relevance.

Abu Shehab M, Khosravi J, Han VK, Shilton BH, Gupta MB.

J Proteome Res. 2010 Apr 5;9(4):1873-81. doi: 10.1021/pr900987n.

PMID:
20143870
15.

Stimulation of the maltose transporter ATPase by unliganded maltose binding protein.

Gould AD, Telmer PG, Shilton BH.

Biochemistry. 2009 Aug 25;48(33):8051-61. doi: 10.1021/bi9007066.

16.

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

Kleine H, Poreba E, Lesniewicz K, Hassa PO, Hottiger MO, Litchfield DW, Shilton BH, L├╝scher B.

Mol Cell. 2008 Oct 10;32(1):57-69. doi: 10.1016/j.molcel.2008.08.009.

17.

The dual histidine motif in the active site of Pin1 has a structural rather than catalytic role.

Bailey ML, Shilton BH, Brandl CJ, Litchfield DW.

Biochemistry. 2008 Nov 4;47(44):11481-9. doi: 10.1021/bi800964q. Epub 2008 Oct 10.

PMID:
18844375
18.

Analysis of the isolated SecA DEAD motor suggests a mechanism for chemical-mechanical coupling.

Nithianantham S, Shilton BH.

J Mol Biol. 2008 Nov 7;383(2):380-9. doi: 10.1016/j.jmb.2008.08.022. Epub 2008 Aug 22.

PMID:
18761349
19.

The dynamics of the MBP-MalFGK(2) interaction: a prototype for binding protein dependent ABC-transporter systems.

Shilton BH.

Biochim Biophys Acta. 2008 Sep;1778(9):1772-80. Epub 2007 Sep 19. Review.

20.

Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.

Tang X, Orlicky S, Lin Z, Willems A, Neculai D, Ceccarelli D, Mercurio F, Shilton BH, Sicheri F, Tyers M.

Cell. 2007 Jun 15;129(6):1165-76.

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