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Results: 1 to 20 of 215

1.

The COP9 signalosome is vital for timely repair of DNA double-strand breaks.

Meir M, Galanty Y, Kashani L, Blank M, Khosravi R, Fernández-Ávila MJ, Cruz-García A, Star A, Shochot L, Thomas Y, Garrett LJ, Chamovitz DA, Bodine DM, Kurz T, Huertas P, Ziv Y, Shiloh Y.

Nucleic Acids Res. 2015 May 19;43(9):4517-30. doi: 10.1093/nar/gkv270. Epub 2015 Apr 8.

2.

ATM: expanding roles as a chief guardian of genome stability.

Shiloh Y.

Exp Cell Res. 2014 Nov 15;329(1):154-61. doi: 10.1016/j.yexcr.2014.09.002. Epub 2014 Sep 8. Review. No abstract available.

PMID:
25218947
3.

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.

Rashi-Elkeles S, Warnatz HJ, Elkon R, Kupershtein A, Chobod Y, Paz A, Amstislavskiy V, Sultan M, Safer H, Nietfeld W, Lehrach H, Shamir R, Yaspo ML, Shiloh Y.

Sci Signal. 2014 May 13;7(325):rs3. doi: 10.1126/scisignal.2005032.

PMID:
24825921
4.

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Shiloh Y, Ziv Y.

Nat Rev Mol Cell Biol. 2013 Apr;14(4):197-210. Review.

PMID:
23847781
5.

DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population.

Rasmussen LJ, Shiloh Y, Bergersen LH, Sander M, Bohr VA, Tønjum T.

Mech Ageing Dev. 2013 Oct;134(10):427-33. doi: 10.1016/j.mad.2013.05.001. Epub 2013 May 10. Review. No abstract available.

6.

Studying the cerebellar DNA damage response in the tissue culture dish.

Tzur-Gilat A, Ziv Y, Mittelman L, Barzilai A, Shiloh Y.

Mech Ageing Dev. 2013 Oct;134(10):496-505. doi: 10.1016/j.mad.2013.04.001. Epub 2013 Apr 9.

PMID:
23583690
7.

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.

Shiloh Y, Ziv Y.

Nat Rev Mol Cell Biol. 2013 Apr;14(4):197-210. doi: 10.1038/nrm3546. Epub 2013 Mar 13. Review.

PMID:
23486281
8.

The ATM protein: the importance of being active.

Shiloh Y, Ziv Y.

J Cell Biol. 2012 Aug 6;198(3):273-5. doi: 10.1083/jcb.201207063.

9.

Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.

Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z, van Vliet N, Chen DJ, Hu MC, Kanaar R, Ziv Y, Shiloh Y.

Cell Cycle. 2011 Dec 15;10(24):4300-10. doi: 10.4161/cc.10.24.18642. Epub 2011 Dec 15.

10.

Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain.

Kirshner M, Galron R, Frenkel D, Mandelbaum G, Shiloh Y, Wang ZQ, Barzilai A.

J Mol Neurosci. 2012 Mar;46(3):554-68. doi: 10.1007/s12031-011-9643-y. Epub 2011 Sep 16.

PMID:
21922345
11.

Matrin 3 binds and stabilizes mRNA.

Salton M, Elkon R, Borodina T, Davydov A, Yaspo ML, Halperin E, Shiloh Y.

PLoS One. 2011;6(8):e23882. doi: 10.1371/journal.pone.0023882. Epub 2011 Aug 17.

12.

RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.

Shiloh Y, Shema E, Moyal L, Oren M.

FEBS Lett. 2011 Sep 16;585(18):2795-802. doi: 10.1016/j.febslet.2011.07.034. Epub 2011 Aug 4. Review.

13.

Transcriptional modulation induced by ionizing radiation: p53 remains a central player.

Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

Mol Oncol. 2011 Aug;5(4):336-48. doi: 10.1016/j.molonc.2011.06.004. Epub 2011 Jul 7. Review.

14.

A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia.

Raz-Prag D, Galron R, Segev-Amzaleg N, Solomon AS, Shiloh Y, Barzilai A, Frenkel D.

Am J Pathol. 2011 Sep;179(3):1533-41. doi: 10.1016/j.ajpath.2011.05.026. Epub 2011 Jul 19.

15.

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair.

Segal-Raz H, Mass G, Baranes-Bachar K, Lerenthal Y, Wang SY, Chung YM, Ziv-Lehrman S, Ström CE, Helleday T, Hu MC, Chen DJ, Shiloh Y.

EMBO Rep. 2011 Jul 1;12(7):713-9. doi: 10.1038/embor.2011.96.

16.

Beyond ATM: the protein kinase landscape of the DNA damage response.

Bensimon A, Aebersold R, Shiloh Y.

FEBS Lett. 2011 Jun 6;585(11):1625-39. doi: 10.1016/j.febslet.2011.05.013. Epub 2011 May 8. Review.

17.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y.

Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015.

18.

Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.

Dar I, Yosha G, Elfassy R, Galron R, Wang ZQ, Shiloh Y, Barzilai A.

J Biol Chem. 2011 Apr 29;286(17):15361-76. doi: 10.1074/jbc.M110.204172. Epub 2011 Feb 7.

19.

Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model.

Galron R, Gruber R, Lifshitz V, Lu H, Kirshner M, Ziv N, Wang ZQ, Shiloh Y, Barzilai A, Frenkel D.

J Mol Neurosci. 2011 Oct;45(2):202-11. doi: 10.1007/s12031-011-9494-6. Epub 2011 Jan 29.

PMID:
21279473
20.

KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin.

Kepkay R, Attwood KM, Ziv Y, Shiloh Y, Dellaire G.

Cell Cycle. 2011 Jan 15;10(2):308-22. Epub 2011 Jan 15.

PMID:
21228624
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