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Results: 1 to 20 of 55

1.

Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease.

Lindahl GE, Stock CJ, Shi-Wen X, Leoni P, Sestini P, Howat SL, Bou-Gharios G, Nicholson AG, Denton CP, Grutters JC, Maher TM, Wells AU, Abraham DJ, Renzoni EA.

Respir Res. 2013 Aug 2;14:80. doi: 10.1186/1465-9921-14-80.

PMID:
23915349
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts.

Shi-wen X, Thompson K, Khan K, Liu S, Murphy-Marshman H, Baron M, Denton CP, Leask A, Abraham DJ.

Rheumatology (Oxford). 2012 Dec;51(12):2146-54. doi: 10.1093/rheumatology/kes234. Epub 2012 Sep 12.

PMID:
22977060
[PubMed - indexed for MEDLINE]
3.

Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.

Thoua NM, Derrett-Smith EC, Khan K, Dooley A, Shi-Wen X, Denton CP.

Rheumatology (Oxford). 2012 Nov;51(11):1989-98. doi: 10.1093/rheumatology/kes191. Epub 2012 Aug 20.

PMID:
22908328
[PubMed - indexed for MEDLINE]
4.

The vasa vasorum and associated endothelial nitric oxide synthase is more important for saphenous vein than arterial bypass grafts.

Dreifaldt M, Souza D, Bodin L, Shi-Wen X, Dooley A, Muddle J, Loesch A, Dashwood MR.

Angiology. 2013 May;64(4):293-9. doi: 10.1177/0003319712443729. Epub 2012 May 7.

PMID:
22569406
[PubMed - indexed for MEDLINE]
5.

Nitric oxide manipulation: a therapeutic target for peripheral arterial disease?

Williams G, Shi-Wen X, Abraham D, Selvakumar S, Baker DM, Tsui JC.

Cardiol Res Pract. 2012;2012:656247. doi: 10.1155/2012/656247. Epub 2012 Mar 20.

PMID:
22536531
[PubMed]
Free PMC Article
6.

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation.

Lagares D, Busnadiego O, García-Fernández RA, Kapoor M, Liu S, Carter DE, Abraham D, Shi-Wen X, Carreira P, Fontaine BA, Shea BS, Tager AM, Leask A, Lamas S, Rodríguez-Pascual F.

Arthritis Rheum. 2012 May;64(5):1653-64. doi: 10.1002/art.33482.

PMID:
22492165
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Toll-like receptors in ischaemia and its potential role in the pathophysiology of muscle damage in critical limb ischaemia.

Patel H, Shaw SG, Shi-Wen X, Abraham D, Baker DM, Tsui JC.

Cardiol Res Pract. 2012;2012:121237. doi: 10.1155/2012/121237. Epub 2012 Feb 7.

PMID:
22454775
[PubMed]
Free PMC Article
8.

Elevated CCN2 expression in scleroderma: a putative role for the TGFβ accessory receptors TGFβRIII and endoglin.

Holmes AM, Ponticos M, Shi-Wen X, Denton CP, Abraham DJ.

J Cell Commun Signal. 2011 Aug;5(3):173-7. doi: 10.1007/s12079-011-0140-4. Epub 2011 Jul 19.

PMID:
21769684
[PubMed]
Free PMC Article
9.

Loss of PTEN expression by dermal fibroblasts causes skin fibrosis.

Parapuram SK, Shi-wen X, Elliott C, Welch ID, Jones H, Baron M, Denton CP, Abraham DJ, Leask A.

J Invest Dermatol. 2011 Oct;131(10):1996-2003. doi: 10.1038/jid.2011.156. Epub 2011 Jun 9.

PMID:
21654839
[PubMed - indexed for MEDLINE]
Free Article
10.

Identification of neuronal nitric oxide synthase (nNOS) in human penis: a potential role of reduced neuronally-derived nitric oxide in erectile dysfunction.

Dashwood MR, Crump A, Shi-Wen X, Loesch A.

Curr Pharm Biotechnol. 2011 Sep;12(9):1316-21.

PMID:
21506911
[PubMed - indexed for MEDLINE]
11.

Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism.

Chen Y, Leask A, Abraham DJ, Kennedy L, Shi-Wen X, Denton CP, Black CM, Verjee LS, Eastwood M.

Fibrogenesis Tissue Repair. 2011 Mar 31;4(1):9. doi: 10.1186/1755-1536-4-9.

PMID:
21453480
[PubMed]
Free PMC Article
12.

Endothelin-1 stimulates colon cancer adjacent fibroblasts.

Knowles JP, Shi-Wen X, Haque SU, Bhalla A, Dashwood MR, Yang S, Taylor I, Winslet MC, Abraham DJ, Loizidou M.

Int J Cancer. 2012 Mar 15;130(6):1264-72. doi: 10.1002/ijc.26090. Epub 2011 Jun 9.

PMID:
21445967
[PubMed - indexed for MEDLINE]
13.

Endothelin-1 in peripheral arterial disease: a potential role in muscle damage.

Tsui JC, Shi-Wen X.

Pharmacol Res. 2011 Jun;63(6):473-6. doi: 10.1016/j.phrs.2011.02.012. Epub 2011 Mar 5. Review.

PMID:
21382494
[PubMed - indexed for MEDLINE]
14.

mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.

McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M.

Arthritis Res Ther. 2011;13(1):R6. doi: 10.1186/ar3226. Epub 2011 Jan 25. Erratum in: Arthritis Res Ther. 2011;13(2):402.

PMID:
21266028
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Perivascular fat-derived leptin: a potential role in improved vein graft performance in coronary artery bypass surgery.

Dashwood MR, Dooley A, Shi-Wen X, Abraham DJ, Dreifaldt M, Souza DS.

Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):170-3. doi: 10.1510/icvts.2010.247874. Epub 2010 Nov 3.

PMID:
21051379
[PubMed - indexed for MEDLINE]
Free Article
16.

CCN2 is required for bleomycin-induced skin fibrosis in mice.

Liu S, Shi-wen X, Abraham DJ, Leask A.

Arthritis Rheum. 2011 Jan;63(1):239-46. doi: 10.1002/art.30074.

PMID:
20936632
[PubMed - indexed for MEDLINE]
Free Article
17.

Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate.

Dooley A, Shi-Wen X, Aden N, Tranah T, Desai N, Denton CP, Abraham DJ, Bruckdorfer R.

Rheumatology (Oxford). 2010 Nov;49(11):2024-36. doi: 10.1093/rheumatology/keq208. Epub 2010 Jul 13.

PMID:
20627968
[PubMed - indexed for MEDLINE]
Free Article
18.

Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma.

Derrett-Smith EC, Dooley A, Khan K, Shi-wen X, Abraham D, Denton CP.

Arthritis Res Ther. 2010;12(2):R69. doi: 10.1186/ar2986. Epub 2010 Apr 15.

PMID:
20398328
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis.

Sonnylal S, Shi-Wen X, Leoni P, Naff K, Van Pelt CS, Nakamura H, Leask A, Abraham D, Bou-Gharios G, de Crombrugghe B.

Arthritis Rheum. 2010 May;62(5):1523-32. doi: 10.1002/art.27382.

PMID:
20213804
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts.

Shi-wen X, Eastwood M, Stratton RJ, Denton CP, Leask A, Abraham DJ.

Rheumatology (Oxford). 2010 Feb;49(2):259-63. doi: 10.1093/rheumatology/kep371. Epub 2009 Dec 9.

PMID:
20007285
[PubMed - indexed for MEDLINE]
Free Article

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