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Results: 1 to 20 of 25

1.

Non-targeted identification of prions and amyloid-forming proteins from yeast and mammalian cells.

Kryndushkin D, Pripuzova N, Burnett BG, Shewmaker F.

J Biol Chem. 2013 Sep 20;288(38):27100-11. doi: 10.1074/jbc.M113.485359. Epub 2013 Aug 7.

PMID:
23926098
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.

Daigle JG, Lanson NA Jr, Smith RB, Casci I, Maltare A, Monaghan J, Nichols CD, Kryndushkin D, Shewmaker F, Pandey UB.

Hum Mol Genet. 2013 Mar 15;22(6):1193-205. doi: 10.1093/hmg/dds526. Epub 2012 Dec 20.

PMID:
23257289
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sex, prions, and plasmids in yeast.

Kelly AC, Shewmaker FP, Kryndushkin D, Wickner RB.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):E2683-90. doi: 10.1073/pnas.1213449109. Epub 2012 Sep 4.

PMID:
22949655
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Study of amyloids using yeast.

Wickner RB, Kryndushkin D, Shewmaker F, McGlinchey R, Edskes HK.

Methods Mol Biol. 2012;849:321-46. doi: 10.1007/978-1-61779-551-0_22.

PMID:
22528100
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Modeling ALS and FTLD proteinopathies in yeast: an efficient approach for studying protein aggregation and toxicity.

Kryndushkin D, Shewmaker F.

Prion. 2011 Oct-Dec;5(4):250-7. doi: 10.4161/pri.17229. Epub 2011 Oct 1. Review.

PMID:
22052354
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Amyloid of the Candida albicans Ure2p prion domain is infectious and has an in-register parallel ╬▓-sheet structure.

Engel A, Shewmaker F, Edskes HK, Dyda F, Wickner RB.

Biochemistry. 2011 Jul 12;50(27):5971-8. doi: 10.1021/bi200142x. Epub 2011 Jun 15.

PMID:
21634787
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structural insights into functional and pathological amyloid.

Shewmaker F, McGlinchey RP, Wickner RB.

J Biol Chem. 2011 May 13;286(19):16533-40. doi: 10.1074/jbc.R111.227108. Epub 2011 Mar 25. Review.

PMID:
21454545
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The relationship of prions and translation.

Wickner RB, Edskes HK, Shewmaker FP, Kryndushkin D, Nemecek J, McGlinchey R, Bateman D.

Wiley Interdiscip Rev RNA. 2010 Jul-Aug;1(1):81-9. doi: 10.1002/wrna.8. Review.

PMID:
21339834
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Repeat domains of melanosome matrix protein Pmel17 orthologs form amyloid fibrils at the acidic melanosomal pH.

McGlinchey RP, Shewmaker F, Hu KN, McPhie P, Tycko R, Wickner RB.

J Biol Chem. 2011 Mar 11;286(10):8385-93. doi: 10.1074/jbc.M110.197152. Epub 2010 Dec 10.

PMID:
21148556
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Prion amyloid structure explains templating: how proteins can be genes.

Wickner RB, Shewmaker F, Edskes H, Kryndushkin D, Nemecek J, McGlinchey R, Bateman D, Winchester CL.

FEMS Yeast Res. 2010 Dec;10(8):980-91. doi: 10.1111/j.1567-1364.2010.00666.x. Review.

PMID:
20726897
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Quantitative characterization of heparin binding to Tau protein: implication for inducer-mediated Tau filament formation.

Zhu HL, Fernández C, Fan JB, Shewmaker F, Chen J, Minton AP, Liang Y.

J Biol Chem. 2010 Feb 5;285(6):3592-9. doi: 10.1074/jbc.M109.035691. Epub 2009 Dec 3.

PMID:
19959468
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Crowded cell-like environment accelerates the nucleation step of amyloidogenic protein misfolding.

Zhou Z, Fan JB, Zhu HL, Shewmaker F, Yan X, Chen X, Chen J, Xiao GF, Guo L, Liang Y.

J Biol Chem. 2009 Oct 30;284(44):30148-58. doi: 10.1074/jbc.M109.002832. Epub 2009 Sep 10.

PMID:
19748895
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Measurement of amyloid fibril mass-per-length by tilted-beam transmission electron microscopy.

Chen B, Thurber KR, Shewmaker F, Wickner RB, Tycko R.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14339-44. doi: 10.1073/pnas.0907821106. Epub 2009 Aug 11.

PMID:
19706519
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis.

McGlinchey RP, Shewmaker F, McPhie P, Monterroso B, Thurber K, Wickner RB.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13731-6. doi: 10.1073/pnas.0906509106. Epub 2009 Jul 31.

PMID:
19666488
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The functional curli amyloid is not based on in-register parallel beta-sheet structure.

Shewmaker F, McGlinchey RP, Thurber KR, McPhie P, Dyda F, Tycko R, Wickner RB.

J Biol Chem. 2009 Sep 11;284(37):25065-76. doi: 10.1074/jbc.M109.007054. Epub 2009 Jul 1.

PMID:
19574225
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Prion variants, species barriers, generation and propagation.

Wickner RB, Edskes HK, Shewmaker F, Kryndushkin D, Nemecek J.

J Biol. 2009;8(5):47. doi: 10.1186/jbiol148. Epub 2009 May 26. Review.

PMID:
19519931
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Two prion variants of Sup35p have in-register parallel beta-sheet structures, independent of hydration.

Shewmaker F, Kryndushkin D, Chen B, Tycko R, Wickner RB.

Biochemistry. 2009 Jun 16;48(23):5074-82. doi: 10.1021/bi900345q.

PMID:
19408895
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Curing of the [URE3] prion by Btn2p, a Batten disease-related protein.

Kryndushkin DS, Shewmaker F, Wickner RB.

EMBO J. 2008 Oct 22;27(20):2725-35. doi: 10.1038/emboj.2008.198. Epub 2008 Oct 2.

PMID:
18833194
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Protein inheritance (prions) based on parallel in-register beta-sheet amyloid structures.

Wickner RB, Shewmaker F, Kryndushkin D, Edskes HK.

Bioessays. 2008 Oct;30(10):955-64. doi: 10.1002/bies.20821. Review.

PMID:
18798523
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Prions of fungi: inherited structures and biological roles.

Wickner RB, Edskes HK, Shewmaker F, Nakayashiki T.

Nat Rev Microbiol. 2007 Aug;5(8):611-8. Review.

PMID:
17632572
[PubMed - indexed for MEDLINE]
Free PMC Article
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