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Results: 1 to 20 of 61


The Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human Cancer.

Meng E, Hanna A, Samant RS, Shevde LA.

Cancers (Basel). 2015 Jul 21;7(3):1333-48. doi: 10.3390/cancers7030839. Review.


N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells.

Metge BJ, Mitra A, Chen D, Shevde LA, Samant RS.

Sci Rep. 2015 Jul 6;5:11995. doi: 10.1038/srep11995.


NMI and EMT.

Samant RS, Shevde LA.

Oncoscience. 2014 Jun 19;1(7):476-7. eCollection 2014. No abstract available.


ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling.

Meng E, Mitra A, Tripathi K, Finan MA, Scalici J, McClellan S, Madeira da Silva L, Reed E, Shevde LA, Palle K, Rocconi RP.

PLoS One. 2014 Sep 12;9(9):e107142. doi: 10.1371/journal.pone.0107142. eCollection 2014.


microRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancer.

Rostas JW 3rd, Pruitt HC, Metge BJ, Mitra A, Bailey SK, Bae S, Singh KP, Devine DJ, Dyess DL, Richards WO, Tucker JA, Shevde LA, Samant RS.

Mol Cancer. 2014 Aug 29;13:200. doi: 10.1186/1476-4598-13-200.


Role of osteopontin in the pathophysiology of cancer.

Shevde LA, Samant RS.

Matrix Biol. 2014 Jul;37:131-41. doi: 10.1016/j.matbio.2014.03.001. Epub 2014 Mar 19. Review.


GLI1 upregulates C-JUN through a specific 130-kDa isoform.

Amable L, Gavin E, Kudo K, Meng E, Rocconi RP, Shevde LA, Reed E.

Int J Oncol. 2014 Mar;44(3):655-61. doi: 10.3892/ijo.2013.2222. Epub 2013 Dec 20.


Nonclassical hedgehog-GLI signaling and its clinical implications.

Shevde LA, Samant RS.

Int J Cancer. 2014 Jul 1;135(1):1-6. doi: 10.1002/ijc.28424. Epub 2013 Sep 11. Review.


Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling.

Devine DJ, Rostas JW, Metge BJ, Das S, Mulekar MS, Tucker JA, Grizzle WE, Buchsbaum DJ, Shevde LA, Samant RS.

Oncogene. 2014 May 15;33(20):2620-8. doi: 10.1038/onc.2013.215. Epub 2013 Jun 17.


Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to Smoothened-targeting Hedgehog inhibition.

Das S, Samant RS, Shevde LA.

J Biol Chem. 2013 Apr 26;288(17):11824-33. doi: 10.1074/jbc.M112.432302. Epub 2013 Mar 18.


Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance.

Vincent AJ, Ren S, Harris LG, Devine DJ, Samant RS, Fodstad O, Shevde LA.

FEBS Lett. 2012 Sep 21;586(19):3429-34. doi: 10.1016/j.febslet.2012.07.063. Epub 2012 Jul 31.


Merlin: the wizard requires protein stability to function as a tumor suppressor.

Morrow KA, Shevde LA.

Biochim Biophys Acta. 2012 Dec;1826(2):400-6. doi: 10.1016/j.bbcan.2012.06.005. Epub 2012 Jun 30. Review.


Micro-RNA-632 downregulates DNAJB6 in breast cancer.

Mitra A, Rostas JW, Dyess DL, Shevde LA, Samant RS.

Lab Invest. 2012 Sep;92(9):1310-7. doi: 10.1038/labinvest.2012.87. Epub 2012 Jun 18.


The influence of the cancer microenvironment on the process of metastasis.

Frost AR, Hurst DR, Shevde LA, Samant RS.

Int J Breast Cancer. 2012;2012:756257. doi: 10.1155/2012/756257. Epub 2012 Apr 18. No abstract available.


Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.

Andrews JF, Sykora LJ, Letostak TB, Menezes ME, Mitra A, Barik S, Shevde LA, Samant RS.

Exp Cell Res. 2012 Jun 10;318(10):1086-93. doi: 10.1016/j.yexcr.2012.03.024. Epub 2012 Apr 3.


Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases.

Das S, Tucker JA, Khullar S, Samant RS, Shevde LA.

PLoS One. 2012;7(3):e34374. doi: 10.1371/journal.pone.0034374. Epub 2012 Mar 29.


DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.

Menezes ME, Mitra A, Shevde LA, Samant RS.

Biochem J. 2012 Jun 15;444(3):573-80. doi: 10.1042/BJ20120205.


The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer.

Das S, Samant RS, Shevde LA.

Int J Breast Cancer. 2012;2012:298623. doi: 10.1155/2012/298623. Epub 2011 Dec 1.


Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs.

Li X, Gao L, Cui Q, Gary BD, Dyess DL, Taylor W, Shevde LA, Samant RS, Dean-Colomb W, Piazza GA, Xi Y.

Oncogene. 2012 Nov 29;31(48):4979-86. doi: 10.1038/onc.2011.655. Epub 2012 Jan 30.


Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair.

Kudo K, Gavin E, Das S, Amable L, Shevde LA, Reed E.

Oncogene. 2012 Nov 1;31(44):4718-24. doi: 10.1038/onc.2011.610. Epub 2012 Jan 23.

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