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Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study.

Teare MD, Dimairo M, Shephard N, Hayman A, Whitehead A, Walters SJ.

Trials. 2014 Jul 3;15:264. doi: 10.1186/1745-6215-15-264.


The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids.

Tiernan J, Hind D, Watson A, Wailoo AJ, Bradburn M, Shephard N, Biggs K, Brown S.

BMC Gastroenterol. 2012 Oct 25;12:153. doi: 10.1186/1471-230X-12-153.


Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis.

Glossop AJ, Shephard N, Bryden DC, Mills GH.

Br J Anaesth. 2012 Sep;109(3):305-14. doi: 10.1093/bja/aes270. Review. Erratum in: Br J Anaesth. 2013 Jan;110(1):164. Shepherd, N [corrected to Shephard, N].


Headgroup effect on silane structures at buried polymer/silane and polymer/polymer interfaces and their relations to adhesion.

Zhang C, Shephard NE, Rhodes SM, Chen Z.

Langmuir. 2012 Apr 10;28(14):6052-9. doi: 10.1021/la300004x. Epub 2012 Mar 28.


Pure-tone auditory thresholds are not chronically elevated in multiple sclerosis.

Doty RL, Tourbier I, Davis S, Rotz J, Cuzzocreo JL, Treem J, Shephard N, Pham DL.

Behav Neurosci. 2012 Apr;126(2):314-24. doi: 10.1037/a0027046. Epub 2012 Feb 6.


Phenolic resin surface restructuring upon exposure to humid air: a sum frequency generation vibrational spectroscopic study.

Lu X, Han J, Shephard N, Rhodes S, Martin AD, Li D, Xue G, Chen Z.

J Phys Chem B. 2009 Oct 1;113(39):12944-51. doi: 10.1021/jp9058092.


A breast cancer risk haplotype in the caspase-8 gene.

Shephard ND, Abo R, Rigas SH, Frank B, Lin WY, Brock IW, Shippen A, Balasubramanian SP, Reed MW, Bartram CR, Meindl A, Schmutzler RK, Engel C, Burwinkel B, Cannon-Albright LA, Allen-Brady K, Camp NJ, Cox A.

Cancer Res. 2009 Apr 1;69(7):2724-8. doi: 10.1158/0008-5472.CAN-08-4266. Epub 2009 Mar 24.


Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

Hinks A, Barton A, Shephard N, Eyre S, Bowes J, Cargill M, Wang E, Ke X, Kennedy GC, John S, Worthington J, Thomson W; British Society of Paediatric and Adolescent Rheumatology Study Group.

Arthritis Rheum. 2009 Jan;60(1):258-63. doi: 10.1002/art.24179.


Understanding molecular structures of silanes at buried polymer interfaces using sum frequency generation vibrational spectroscopy and relating interfacial structures to polymer adhesion.

Vázquez AV, Shephard NE, Steinecker CL, Ahn D, Spanninga S, Chen Z.

J Colloid Interface Sci. 2009 Mar 15;331(2):408-16. doi: 10.1016/j.jcis.2008.11.065. Epub 2008 Dec 6.


Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits.

Amos CI, Chen WV, Remmers E, Siminovitch KA, Seldin MF, Criswell LA, Lee AT, John S, Shephard ND, Worthington J, Cornelis F, Plenge RM, Begovich AB, Dyer TD, Kastner DL, Gregersen PK.

BMC Proc. 2007;1 Suppl 1:S3. Epub 2007 Dec 18.


Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus.

Gallego PH, Shephard N, Bulsara MK, van Bockxmeer FM, Powell BL, Beilby JP, Arscott G, Le Page M, Palmer LJ, Davis EA, Jones TW, Choong CS.

J Diabetes Complications. 2008 May-Jun;22(3):191-8. doi: 10.1016/j.jdiacomp.2007.03.003. Epub 2008 Apr 16.


Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes.

Sims AM, Shephard N, Carter K, Doan T, Dowling A, Duncan EL, Eisman J, Jones G, Nicholson G, Prince R, Seeman E, Thomas G, Wass JA, Brown MA.

J Bone Miner Res. 2008 Apr;23(4):499-506.


Association between osteopontin and human abdominal aortic aneurysm.

Golledge J, Muller J, Shephard N, Clancy P, Smallwood L, Moran C, Dear AE, Palmer LJ, Norman PE.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):655-60. Epub 2006 Dec 14.


Fine mapping of genes within the IDDM8 region in rheumatoid arthritis.

Hinks A, Barton A, John S, Shephard N, Worthington J.

Arthritis Res Ther. 2006;8(5):R145.


Linkage analysis of rheumatoid arthritis in US and UK families reveals interactions between HLA-DRB1 and loci on chromosomes 6q and 16p.

John S, Amos C, Shephard N, Chen W, Butterworth A, Etzel C, Jawaheer D, Seldin M, Silman A, Gregersen P, Worthington J.

Arthritis Rheum. 2006 May;54(5):1482-90.


In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype.

Chinoy H, Salway F, Fertig N, Shephard N, Tait BD, Thomson W, Isenberg DA, Oddis CV, Silman AJ, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration (AOMIC).

Arthritis Res Ther. 2006;8(1):R13.


Will the real disease gene please stand up?

Shephard N, John S, Cardon L, McCarthy MI, Zeggini E.

BMC Genet. 2005 Dec 30;6 Suppl 1:S66.


Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites.

John S, Shephard N, Liu G, Zeggini E, Cao M, Chen W, Vasavda N, Mills T, Barton A, Hinks A, Eyre S, Jones KW, Ollier W, Silman A, Gibson N, Worthington J, Kennedy GC.

Am J Hum Genet. 2004 Jul;75(1):54-64. Epub 2004 May 20.


Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.

Eyre S, Barton A, Shephard N, Hinks A, Brintnell W, MacKay K, Silman A, Ollier W, Wordsworth P, John S, Worthington J.

Arthritis Rheum. 2004 Mar;50(3):729-35.

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