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Results: 20

1.

Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.

Ryan DM, Vincent TL, Salit J, Walters MS, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y, Downey RJ, Buro-Auriemma LJ, Staudt MR, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2014 Feb 3;9(2):e88051. doi: 10.1371/journal.pone.0088051. eCollection 2014.

PMID:
24498427
[PubMed - in process]
Free PMC Article
2.

Basal cell origins of smoking-induced airway epithelial disorders.

Shaykhiev R, Crystal RG.

Cell Cycle. 2014 Feb 1;13(3):341-2. doi: 10.4161/cc.27510. Epub 2013 Dec 13. No abstract available.

PMID:
24335435
[PubMed - in process]
Free PMC Article
3.

Innate immunity and chronic obstructive pulmonary disease: a mini-review.

Shaykhiev R, Crystal RG.

Gerontology. 2013;59(6):481-9. doi: 10.1159/000354173. Epub 2013 Sep 3. Review.

PMID:
24008598
[PubMed - indexed for MEDLINE]
Free Article
4.

Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer.

Shaykhiev R, Wang R, Zwick RK, Hackett NR, Leung R, Moore MA, Sima CS, Chao IW, Downey RJ, Strulovici-Barel Y, Salit J, Crystal RG.

Stem Cells. 2013 Sep;31(9):1992-2002. doi: 10.1002/stem.1459.

PMID:
23857717
[PubMed - indexed for MEDLINE]
5.

EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype.

Shaykhiev R, Zuo WL, Chao I, Fukui T, Witover B, Brekman A, Crystal RG.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12102-7. doi: 10.1073/pnas.1303058110. Epub 2013 Jul 1.

PMID:
23818594
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Lung adenocarcinoma subtypes based on expression of human airway basal cell genes.

Fukui T, Shaykhiev R, Agosto-Perez F, Mezey JG, Downey RJ, Travis WD, Crystal RG.

Eur Respir J. 2013 Nov;42(5):1332-44. doi: 10.1183/09031936.00144012. Epub 2013 May 3.

PMID:
23645403
[PubMed - indexed for MEDLINE]
7.

Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer.

Shaykhiev R, Sackrowitz R, Fukui T, Zuo WL, Chao IW, Strulovici-Barel Y, Downey RJ, Crystal RG.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):418-25. doi: 10.1165/rcmb.2012-0396OC.

PMID:
23597004
[PubMed - indexed for MEDLINE]
8.

RNA-Seq quantification of the human small airway epithelium transcriptome.

Hackett NR, Butler MW, Shaykhiev R, Salit J, Omberg L, Rodriguez-Flores JL, Mezey JG, Strulovici-Barel Y, Wang G, Didon L, Crystal RG.

BMC Genomics. 2012 Feb 29;13:82. doi: 10.1186/1471-2164-13-82.

PMID:
22375630
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The human airway epithelial basal cell transcriptome.

Hackett NR, Shaykhiev R, Walters MS, Wang R, Zwick RK, Ferris B, Witover B, Salit J, Crystal RG.

PLoS One. 2011 May 4;6(5):e18378. doi: 10.1371/journal.pone.0018378.

PMID:
21572528
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer.

Butler MW, Fukui T, Salit J, Shaykhiev R, Mezey JG, Hackett NR, Crystal RG.

Cancer Res. 2011 Apr 1;71(7):2572-81. doi: 10.1158/0008-5472.CAN-10-2046. Epub 2011 Feb 16.

PMID:
21325429
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo.

Shaykhiev R, Otaki F, Bonsu P, Dang DT, Teater M, Strulovici-Barel Y, Salit J, Harvey BG, Crystal RG.

Cell Mol Life Sci. 2011 Mar;68(5):877-92. doi: 10.1007/s00018-010-0500-x. Epub 2010 Sep 6.

PMID:
20820852
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The antimicrobial peptide cathelicidin enhances activation of lung epithelial cells by LPS.

Shaykhiev R, Sierigk J, Herr C, Krasteva G, Kummer W, Bals R.

FASEB J. 2010 Dec;24(12):4756-66. doi: 10.1096/fj.09-151332. Epub 2010 Aug 9.

PMID:
20696857
[PubMed - indexed for MEDLINE]
Free Article
13.

Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome?

Dvorak A, Tilley AE, Shaykhiev R, Wang R, Crystal RG.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):465-73. doi: 10.1165/rcmb.2009-0453OC. Epub 2010 Jun 4.

PMID:
20525805
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.

Shaykhiev R, Krause A, Salit J, Strulovici-Barel Y, Harvey BG, O'Connor TP, Crystal RG.

J Immunol. 2009 Aug 15;183(4):2867-83. doi: 10.4049/jimmunol.0900473. Epub 2009 Jul 27.

PMID:
19635926
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival.

Shaykhiev R, Behr J, Bals R.

PLoS One. 2008 Jan 2;3(1):e1393. doi: 10.1371/journal.pone.0001393.

PMID:
18167552
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells.

von Haussen J, Koczulla R, Shaykhiev R, Herr C, Pinkenburg O, Reimer D, Wiewrodt R, Biesterfeld S, Aigner A, Czubayko F, Bals R.

Lung Cancer. 2008 Jan;59(1):12-23. Epub 2007 Aug 31.

PMID:
17764778
[PubMed - indexed for MEDLINE]
17.

The role of cathelicidin and defensins in pulmonary inflammatory diseases.

Herr C, Shaykhiev R, Bals R.

Expert Opin Biol Ther. 2007 Sep;7(9):1449-61. Review.

PMID:
17727333
[PubMed - indexed for MEDLINE]
18.

Interactions between epithelial cells and leukocytes in immunity and tissue homeostasis.

Shaykhiev R, Bals R.

J Leukoc Biol. 2007 Jul;82(1):1-15. Epub 2007 Apr 23. Review.

PMID:
17452476
[PubMed - indexed for MEDLINE]
Free Article
19.

The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands.

Kandler K, Shaykhiev R, Kleemann P, Klescz F, Lohoff M, Vogelmeier C, Bals R.

Int Immunol. 2006 Dec;18(12):1729-36. Epub 2006 Oct 13.

PMID:
17041145
[PubMed - indexed for MEDLINE]
Free Article
20.

Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure.

Shaykhiev R, Beisswenger C, Kändler K, Senske J, Püchner A, Damm T, Behr J, Bals R.

Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L842-8. Epub 2005 Jun 17.

PMID:
15964896
[PubMed - indexed for MEDLINE]
Free Article

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