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Results: 1 to 20 of 602

1.

Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes.

Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE, Shaw PJ, Kirby J, Veldink JH, Macklis JD, Powell JF, Al-Chalabi A.

Neurobiol Aging. 2015 Feb 19. pii: S0197-4580(15)00117-7. doi: 10.1016/j.neurobiolaging.2015.02.017. [Epub ahead of print]

PMID:
25801576
2.

Destined for indecision? A critical analysis of waste management practices in England from 1996 to 2013.

Farmer TD, Shaw PJ, Williams ID.

Waste Manag. 2015 Mar 12. pii: S0956-053X(15)00125-7. doi: 10.1016/j.wasman.2015.02.023. [Epub ahead of print]

PMID:
25771762
3.

The Spectrum of C9orf72-mediated Neurodegeneration and Amyotrophic Lateral Sclerosis.

Cooper-Knock J, Kirby J, Highley R, Shaw PJ.

Neurotherapeutics. 2015 Mar 3. [Epub ahead of print]

PMID:
25731823
4.

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment.

Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE, Wharton SB; MRC Cognitive Function and Ageing Neuropathology Study Group.

PLoS One. 2015 Feb 23;10(2):e0118463. doi: 10.1371/journal.pone.0118463. eCollection 2015.

5.

How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila.

Faville R, Kottler B, Goodhill GJ, Shaw PJ, van Swinderen B.

Sci Rep. 2015 Feb 13;5:8454. doi: 10.1038/srep08454.

6.

A New Model to Study Sleep Deprivation-Induced Seizure.

Lucey BP, Leahy A, Rosas R, Shaw PJ.

Sleep. 2014 Nov 9. pii: sp-00337-14. [Epub ahead of print]

PMID:
25515102
7.

Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption.

Dissel S, Seugnet L, Thimgan MS, Silverman N, Angadi V, Thacher PV, Burnham MM, Shaw PJ.

Brain Behav Immun. 2014 Oct 30. pii: S0889-1591(14)00472-3. doi: 10.1016/j.bbi.2014.09.019. [Epub ahead of print]

PMID:
25451614
8.

Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins.

Wongsombat C, Aroonsri A, Kamchonwongpaisan S, Morgan HP, Walkinshaw MD, Yuthavong Y, Shaw PJ.

Mol Biochem Parasitol. 2014 Nov;198(1):1-10. doi: 10.1016/j.molbiopara.2014.10.005. Epub 2014 Nov 3.

PMID:
25447287
9.

A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the MRC-CFAS ageing brain cohort.

Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A, Wharton SB; MRC Cognitive Function and Ageing Neuropathology Study Group.

Neuropathol Appl Neurobiol. 2014 Dec 1. doi: 10.1111/nan.12202. [Epub ahead of print]

PMID:
25443110
10.

Intermediate length C9orf72 expansion in an ALS patient without classical C9orf72 neuropathology.

Beer AM, Cooper-Knock J, Higginbottom A, Highley JR, Wharton SB, Ince PG, Milano A, Jones AA, Al-Chalabi A, Kirby J, Shaw PJ.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec 1:1-3. [Epub ahead of print] No abstract available.

PMID:
25436637
11.

Identification of Genes Associated With Resilience/Vulnerability to Sleep Deprivation and Starvation in Drosophila.

Thimgan MS, Seugnet L, Turk J, Shaw PJ.

Sleep. 2014 Nov 20. pii: sp-00336-14. [Epub ahead of print]

PMID:
25409104
12.

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW, Calini D, Vance C, Danielson EW, Troakes C, Tiloca C, Al-Sarraj S, Lewis EA, King A, Colombrita C, Pensato V, Castellotti B, de Belleroche J, Baas F, ten Asbroek AL, Sapp PC, McKenna-Yasek D, McLaughlin RL, Polak M, Asress S, Esteban-Pérez J, Muñoz-Blanco JL, Simpson M; SLAGEN Consortium, van Rheenen W, Diekstra FP, Lauria G, Duga S, Corti S, Cereda C, Corrado L, Sorarù G, Morrison KE, Williams KL, Nicholson GA, Blair IP, Dion PA, Leblond CS, Rouleau GA, Hardiman O, Veldink JH, van den Berg LH, Al-Chalabi A, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, García-Redondo A, Wu Z, Glass JD, Gellera C, Ratti A, Brown RH Jr, Silani V, Shaw CE, Landers JE.

Neuron. 2014 Oct 22;84(2):324-31. doi: 10.1016/j.neuron.2014.09.027. Epub 2014 Oct 22.

PMID:
25374358
13.

PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy.

Little D, Valori CF, Mutsaers CA, Bennett EJ, Wyles M, Sharrack B, Shaw PJ, Gillingwater TH, Azzouz M, Ning K.

Mol Ther. 2015 Feb;23(2):270-7. doi: 10.1038/mt.2014.209. Epub 2014 Nov 5.

PMID:
25369768
14.

Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.

Walsh MJ, Cooper-Knock J, Dodd JE, Stopford MJ, Mihaylov SR, Kirby J, Shaw PJ, Hautbergue GM.

Neuropathol Appl Neurobiol. 2015 Feb;41(2):109-34. doi: 10.1111/nan.12187.

15.

Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia.

Sutton R, Shaw PJ, Venn NC, Law T, Dissanayake A, Kilo T, Haber M, Norris MD, Fraser C, Alvaro F, Revesz T, Trahair TN, Dalla-Pozza L, Marshall GM, O'Brien TA.

Br J Haematol. 2015 Feb;168(3):395-404. doi: 10.1111/bjh.13142. Epub 2014 Oct 14.

PMID:
25312094
16.

Early detection of motor dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis (ALS) using home cage running wheels.

Bennett EJ, Mead RJ, Azzouz M, Shaw PJ, Grierson AJ.

PLoS One. 2014 Sep 30;9(9):e107918. doi: 10.1371/journal.pone.0107918. eCollection 2014.

17.

Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield.

McGeachan AJ, Hobson EV, Shaw PJ, McDermott CJ.

Amyotroph Lateral Scler Frontotemporal Degener. 2015 Mar;16(1-2):108-13. doi: 10.3109/21678421.2014.951942. Epub 2014 Sep 16.

PMID:
25225845
18.

CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.

Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S.

J Clin Invest. 2014 Oct;124(10):4549-63. doi: 10.1172/JCI76602. Epub 2014 Aug 26.

19.

Genetic rescue of functional senescence in synaptic and behavioral plasticity.

Donlea JM, Ramanan N, Silverman N, Shaw PJ.

Sleep. 2014 Sep 1;37(9):1427-37. doi: 10.5665/sleep.3988.

20.

Not too little, not too much-just right! (Better ways to give high dose melphalan).

Shaw PJ, Nath CE, Lazarus HM.

Bone Marrow Transplant. 2014 Dec;49(12):1457-65. doi: 10.1038/bmt.2014.186. Epub 2014 Aug 18.

PMID:
25133893
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