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Results: 1 to 20 of 589

1.

Decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.

Walsh MJ, Cooper-Knock J, Dodd JE, Stopford MJ, Mihaylov SR, Kirby J, Shaw PJ, Hautbergue GM.

Neuropathol Appl Neurobiol. 2014 Oct 16. doi: 10.1111/nan.12187. [Epub ahead of print]

PMID:
25319671
[PubMed - as supplied by publisher]
2.

Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia.

Sutton R, Shaw PJ, Venn NC, Law T, Dissanayake A, Kilo T, Haber M, Norris MD, Fraser C, Alvaro F, Revesz T, Trahair TN, Dalla-Pozza L, Marshall GM, O'Brien TA.

Br J Haematol. 2014 Oct 14. doi: 10.1111/bjh.13142. [Epub ahead of print]

PMID:
25312094
[PubMed - as supplied by publisher]
3.

Early Detection of Motor Dysfunction in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels.

Bennett EJ, Mead RJ, Azzouz M, Shaw PJ, Grierson AJ.

PLoS One. 2014 Sep 30;9(9):e107918. doi: 10.1371/journal.pone.0107918. eCollection 2014.

PMID:
25268710
[PubMed - in process]
Free PMC Article
4.

Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield.

McGeachan AJ, Hobson EV, Shaw PJ, McDermott CJ.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep 16:1-6. [Epub ahead of print]

PMID:
25225845
[PubMed - as supplied by publisher]
5.

CD4+ and CD8+ T cell-dependent antiviral immunity requires STIM1 and STIM2.

Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S.

J Clin Invest. 2014 Oct 1;124(10):4549-63. doi: 10.1172/JCI76602. Epub 2014 Aug 26.

PMID:
25157823
[PubMed - in process]
6.

Genetic rescue of functional senescence in synaptic and behavioral plasticity.

Donlea JM, Ramanan N, Silverman N, Shaw PJ.

Sleep. 2014 Sep 1;37(9):1427-37. doi: 10.5665/sleep.3988.

PMID:
25142573
[PubMed - in process]
7.

Not too little, not too much-just right! (Better ways to give high dose melphalan).

Shaw PJ, Nath CE, Lazarus HM.

Bone Marrow Transplant. 2014 Aug 18. doi: 10.1038/bmt.2014.186. [Epub ahead of print]

PMID:
25133893
[PubMed - as supplied by publisher]
8.

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

Marino M, Papa S, Crippa V, Nardo G, Peviani M, Cheroni C, Trolese MC, Lauranzano E, Bonetto V, Poletti A, DeBiasi S, Ferraiuolo L, Shaw PJ, Bendotti C.

Neurobiol Aging. 2014 Jul 2. pii: S0197-4580(14)00465-5. doi: 10.1016/j.neurobiolaging.2014.06.026. [Epub ahead of print]

PMID:
25085783
[PubMed - as supplied by publisher]
9.

Variation in indigenous forest resource use in central Guyana.

Ozanne CM, Cabral C, Shaw PJ.

PLoS One. 2014 Jul 28;9(7):e102952. doi: 10.1371/journal.pone.0102952. eCollection 2014.

PMID:
25068801
[PubMed - in process]
Free PMC Article
10.

PTEX is an essential nexus for protein export in malaria parasites.

Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan JA, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS, Gilson PR, de Koning-Ward TF.

Nature. 2014 Jul 31;511(7511):587-91. doi: 10.1038/nature13555. Epub 2014 Jul 16.

PMID:
25043043
[PubMed - indexed for MEDLINE]
11.

Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, Boddey JA.

PLoS Biol. 2014 Jul 1;12(7):e1001897. doi: 10.1371/journal.pbio.1001897. eCollection 2014 Jul.

PMID:
24983235
[PubMed - in process]
Free PMC Article
12.

A zebrafish model exemplifies the long preclinical period of motor neuron disease.

Ramesh TM, Shaw PJ, McDearmid J.

J Neurol Neurosurg Psychiatry. 2014 Nov;85(11):1288-9. doi: 10.1136/jnnp-2014-308288. Epub 2014 Jun 26. No abstract available.

PMID:
24970908
[PubMed - in process]
Free Article
13.

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH Jr, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, van Damme P, Melki J, Meininger V, Shatunov A, Shaw CE, Leigh PN, Shaw PJ, Morrison KE, Fogh I, Chiò A, Traynor BJ, Czell D, Weber M, Heutink P, de Bakker PI, Silani V, Robberecht W, van den Berg LH, Veldink JH.

Ann Neurol. 2014 Jul;76(1):120-33. doi: 10.1002/ana.24198. Epub 2014 Jun 27.

PMID:
24931836
[PubMed - indexed for MEDLINE]
14.

Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.

Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ.

Brain. 2014 Jul;137(Pt 7):2040-51. doi: 10.1093/brain/awu120. Epub 2014 May 27.

PMID:
24866055
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the MRC-CFAS cohort.

Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG, Wharton SB; MRC Cognitive Function and Ageing Study.

Neuropathol Appl Neurobiol. 2014 May 27. doi: 10.1111/nan.12156. [Epub ahead of print]

PMID:
24861546
[PubMed - as supplied by publisher]
16.

The impact of gastrostomy in motor neurone disease: challenges and benefits from a patient and carer perspective.

Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ.

BMJ Support Palliat Care. 2014 May 21. pii: bmjspcare-2013-000609. doi: 10.1136/bmjspcare-2013-000609. [Epub ahead of print]

PMID:
24848262
[PubMed - as supplied by publisher]
17.

Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.

Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J, McDermott CJ, Wharton SB, Shaw PJ, Ince PG.

Neuropathol Appl Neurobiol. 2014 Oct;40(6):670-85. doi: 10.1111/nan.12148.

PMID:
24750229
[PubMed - in process]
18.

Gene expression signatures in motor neuron disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions.

Raman R, Allen SP, Goodall EF, Kramer S, Ponger LL, Heath PR, Milo M, Hollinger HC, Walsh T, Highley JR, Olpin S, McDermott CJ, Shaw PJ, Kirby J.

Neuropathol Appl Neurobiol. 2014 Apr 18. doi: 10.1111/nan.12147. [Epub ahead of print]

PMID:
24750211
[PubMed - as supplied by publisher]
Free Article
19.

Factors influencing decision-making in relation to timing of gastrostomy insertion in patients with motor neurone disease.

Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ.

BMJ Support Palliat Care. 2014 Mar;4(1):57-63. doi: 10.1136/bmjspcare-2013-000497. Epub 2013 Dec 11.

PMID:
24644772
[PubMed - in process]
20.

Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis.

Jones AR, Jivraj N, Balendra R, Murphy C, Kelly J, Thornhill M, Young C, Shaw PJ, Leigh PN, Turner MR, Steen IN, McCrone P, Al-Chalabi A.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Jun;15(3-4):285-91. doi: 10.3109/21678421.2013.872149. Epub 2014 Feb 7.

PMID:
24641613
[PubMed - in process]

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