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Items: 1 to 20 of 60

1.

Postexercise High-Fat Feeding Supresses p70S6K1 Activity in Human Skeletal Muscle.

Hammond KM, Impey SG, Currell K, Mitchell N, Shepherd SO, Jeromson S, Hawley JA, Close GL, Hamilton DL, Sharples AP, Morton JP.

Med Sci Sports Exerc. 2016 Jun 20. [Epub ahead of print]

PMID:
27327024
2.

Can clinical prediction tools predict the need for computed tomography in blunt abdominal? A systematic review.

Sharples A, Brohi K.

Injury. 2016 Jun 3. pii: S0020-1383(16)30204-2. doi: 10.1016/j.injury.2016.05.032. [Epub ahead of print]

PMID:
27319389
3.

Fuel for the work required: a practical approach to amalgamating train-low paradigms for endurance athletes.

Impey SG, Hammond KM, Shepherd SO, Sharples AP, Stewart C, Limb M, Smith K, Philp A, Jeromson S, Hamilton DL, Close GL, Morton JP.

Physiol Rep. 2016 May;4(10). pii: e12803. doi: 10.14814/phy2.12803.

4.

Does skeletal muscle have an 'epi'-memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise.

Sharples AP, Stewart CE, Seaborne RA.

Aging Cell. 2016 Aug;15(4):603-16. doi: 10.1111/acel.12486. Epub 2016 Apr 22. Review.

5.

L-glutamine Improves Skeletal Muscle Cell Differentiation and Prevents Myotube Atrophy after Cytokine (TNF-α) Stress via Reduced p38 MAPK Signal Transduction.

Girven M, Dugdale HF, Owens DJ, Hughes DC, Stewart CE, Sharples AP.

J Cell Physiol. 2016 Mar 17. doi: 10.1002/jcp.25380. [Epub ahead of print]

PMID:
26991744
6.

Recalibration of the earthworm tier 1 risk assessment of plant protection products.

Christl H, Bendall J, Bergtold M, Coulson M, Dinter A, Garlej B, Hammel K, Kabouw P, Sharples A, von Mérey G, Vrbka S, Ernst G.

Integr Environ Assess Manag. 2015 Dec 1. doi: 10.1002/ieam.1738. [Epub ahead of print]

PMID:
26620775
7.

Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors.

Hughes DC, Stewart CE, Sculthorpe N, Dugdale HF, Yousefian F, Lewis MP, Sharples AP.

Biogerontology. 2016 Jun;17(3):619-39. doi: 10.1007/s10522-015-9621-9. Epub 2015 Nov 4.

8.

A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy.

Owens DJ, Sharples AP, Polydorou I, Alwan N, Donovan T, Tang J, Fraser WD, Cooper RG, Morton JP, Stewart C, Close GL.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E1019-31. doi: 10.1152/ajpendo.00375.2015. Epub 2015 Oct 27.

PMID:
26506852
9.

Skeletal muscle cells possess a 'memory' of acute early life TNF-α exposure: role of epigenetic adaptation.

Sharples AP, Polydorou I, Hughes DC, Owens DJ, Hughes TM, Stewart CE.

Biogerontology. 2016 Jun;17(3):603-17. doi: 10.1007/s10522-015-9604-x. Epub 2015 Sep 8.

PMID:
26349924
10.

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.

Sharples AP, Hughes DC, Deane CS, Saini A, Selman C, Stewart CE.

Aging Cell. 2015 Aug;14(4):511-23. doi: 10.1111/acel.12342. Epub 2015 Apr 10. Review.

11.

Vein graft aneurysms following popliteal aneurysm repair are more common than we think.

Sharples A, Kay M, Sykes T, Fox A, Houghton A.

Vascular. 2015 Oct;23(5):494-7. doi: 10.1177/1708538114557070. Epub 2014 Oct 20.

PMID:
25331071
12.

The cost-effectiveness of wound-edge protection devices compared to standard care in reducing surgical site infection after laparotomy: an economic evaluation alongside the ROSSINI trial.

Gheorghe A, Roberts TE, Pinkney TD, Bartlett DC, Morton D, Calvert M; West Midlands Research Collaborative; ROSSINI Trial Investigators.

PLoS One. 2014 Apr 18;9(4):e95595. doi: 10.1371/journal.pone.0095595. eCollection 2014.

13.

Multilevel bypass grafting: is it worth it?

Sharples A, Kay M, Sykes T, Fox A, Houghton A.

Ann Vasc Surg. 2014 Oct;28(7):1697-702. doi: 10.1016/j.avsg.2014.03.027. Epub 2014 Apr 3.

PMID:
24704851
14.

Acute mechanical overload increases IGF-I and MMP-9 mRNA in 3D tissue-engineered skeletal muscle.

Player DJ, Martin NR, Passey SL, Sharples AP, Mudera V, Lewis MP.

Biotechnol Lett. 2014 May;36(5):1113-24. doi: 10.1007/s10529-014-1464-y. Epub 2014 Feb 22. Erratum in: Biotechnol Lett. 2014 Jul;36(7):1555-6.

PMID:
24563297
15.

Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial).

Pinkney TD, Calvert M, Bartlett DC, Gheorghe A, Redman V, Dowswell G, Hawkins W, Mak T, Youssef H, Richardson C, Hornby S, Magill L, Haslop R, Wilson S, Morton D; West Midlands Research Collaborative; ROSSINI Trial Investigators.

BMJ. 2013 Jul 31;347:f4305. doi: 10.1136/bmj.f4305.

16.

Impaired hypertrophy in myoblasts is improved with testosterone administration.

Deane CS, Hughes DC, Sculthorpe N, Lewis MP, Stewart CE, Sharples AP.

J Steroid Biochem Mol Biol. 2013 Nov;138:152-61. doi: 10.1016/j.jsbmb.2013.05.005. Epub 2013 May 25.

PMID:
23714396
17.

Factors affecting the structure and maturation of human tissue engineered skeletal muscle.

Martin NR, Passey SL, Player DJ, Khodabukus A, Ferguson RA, Sharples AP, Mudera V, Baar K, Lewis MP.

Biomaterials. 2013 Jul;34(23):5759-65. doi: 10.1016/j.biomaterials.2013.04.002. Epub 2013 May 1.

PMID:
23643182
18.

Massive gastric dilation complicating diabetic gastroparesis.

Ball WR, Sharples AJ.

BMJ Case Rep. 2013 Apr 23;2013. pii: bcr2013009420. doi: 10.1136/bcr-2013-009420.

19.

The role of insulin-like-growth factor binding protein 2 (IGFBP2) and phosphatase and tensin homologue (PTEN) in the regulation of myoblast differentiation and hypertrophy.

Sharples AP, Al-Shanti N, Hughes DC, Lewis MP, Stewart CE.

Growth Horm IGF Res. 2013 Jun;23(3):53-61. doi: 10.1016/j.ghir.2013.03.004. Epub 2013 Apr 11.

PMID:
23583027
20.

The influence of key clinical practices on the knowledge of first year doctors about the patients under their care.

Naqvi M, Ward ST, Dowswell G, Donnelly J; SWIFT group collaborators & the West Midlands Research Collaborative (WMRC).

Int J Clin Pract. 2013 Feb;67(2):181-8. doi: 10.1111/ijcp.12082. Epub 2012 Dec 6.

PMID:
23216806
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