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Results: 1 to 20 of 31

1.

Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells.

Gong C, Zhang Y, Shankaran H, Resat H.

Mol Biosyst. 2015 Jan;11(1):146-58. doi: 10.1039/c4mb00471j. Epub 2014 Oct 15.

PMID:
25315124
2.

ERK oscillation-dependent gene expression patterns and deregulation by stress response.

Waters KM, Cummings BS, Shankaran H, Scholpa NE, Weber TJ.

Chem Res Toxicol. 2014 Sep 15;27(9):1496-503. doi: 10.1021/tx500085u. Epub 2014 Aug 12.

3.

Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3.

Shankaran H, Zhang Y, Tan Y, Resat H.

PLoS Comput Biol. 2013;9(8):e1003201. doi: 10.1371/journal.pcbi.1003201. Epub 2013 Aug 22.

4.

Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis.

von Neubeck C, Shankaran H, Geniza MJ, Kauer PM, Robinson RJ, Chrisler WB, Sowa MB.

Integr Biol (Camb). 2013 Oct;5(10):1229-43. doi: 10.1039/c3ib40071a.

PMID:
23925568
5.

Physiologically-based pharmacokinetic model for Fentanyl in support of the development of Provisional Advisory Levels.

Shankaran H, Adeshina F, Teeguarden JG.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):464-76. doi: 10.1016/j.taap.2013.05.024. Epub 2013 May 31.

PMID:
23732079
6.

Modeling dynamic regulatory processes in stroke.

McDermott JE, Jarman K, Taylor R, Lancaster M, Shankaran H, Vartanian KB, Stevens SL, Stenzel-Poore MP, Sanfilippo A.

PLoS Comput Biol. 2012;8(10):e1002722. doi: 10.1371/journal.pcbi.1002722. Epub 2012 Oct 11.

7.

Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.

Shankaran H, Zhang Y, Chrisler WB, Ewald JA, Wiley HS, Resat H.

Mol Biosyst. 2012 Nov;8(11):2868-82. doi: 10.1039/c2mb25190f. Epub 2012 Sep 5.

8.

Using imaging methods to interrogate radiation-induced cell signaling.

Shankaran H, Weber TJ, von Neubeck C, Sowa MB.

Radiat Res. 2012 Apr;177(4):496-507. Epub 2012 Mar 1. Review.

PMID:
22380462
9.

Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: implications for medical exposures.

von Neubeck C, Shankaran H, Karin NJ, Kauer PM, Chrisler WB, Wang X, Robinson RJ, Waters KM, Tilton SC, Sowa MB.

Environ Mol Mutagen. 2012 May;53(4):247-59. doi: 10.1002/em.21682. Epub 2012 Feb 20.

PMID:
22351304
10.

Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems.

McDermott JE, Shankaran H, Eisfeld AJ, Belisle SE, Neuman G, Li C, McWeeney S, Sabourin C, Kawaoka Y, Katze MG, Waters KM.

BMC Syst Biol. 2011 Nov 11;5:190. doi: 10.1186/1752-0509-5-190.

11.

Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species.

Shankaran H, Chrisler WB, Sontag RL, Weber TJ.

Mol Carcinog. 2011 Jun;50(6):424-32. doi: 10.1002/mc.20724. Epub 2010 Dec 28.

PMID:
21557328
12.

Spatial aspects in biological system simulations.

Resat H, Costa MN, Shankaran H.

Methods Enzymol. 2011;487:485-511. doi: 10.1016/B978-0-12-381270-4.00017-2.

13.

Oscillatory dynamics of the extracellular signal-regulated kinase pathway.

Shankaran H, Wiley HS.

Curr Opin Genet Dev. 2010 Dec;20(6):650-5. doi: 10.1016/j.gde.2010.08.002. Review.

PMID:
20810275
14.

Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.

Joslin EJ, Shankaran H, Opresko LK, Bollinger N, Lauffenburger DA, Wiley HS.

Mol Biosyst. 2010 Jul;6(7):1293-306. doi: 10.1039/c003921g. Epub 2010 May 10.

15.

Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.

Weber TJ, Shankaran H, Wiley HS, Opresko LK, Chrisler WB, Quesenberry RD.

J Invest Dermatol. 2010 May;130(5):1444-56. doi: 10.1038/jid.2009.383. Epub 2009 Dec 17.

16.

Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.

Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS.

Mol Syst Biol. 2009;5:332. doi: 10.1038/msb.2009.90. Epub 2009 Dec 1.

17.

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.

Zhang Y, Opresko L, Shankaran H, Chrisler WB, Wiley HS, Resat H.

BMC Cell Biol. 2009 Oct 31;10:78. doi: 10.1186/1471-2121-10-78.

18.

System theoretical investigation of human epidermal growth factor receptor-mediated signalling.

Zhang Y, Shankaran H, Opresko L, Resat H.

IET Syst Biol. 2008 Sep;2(5):273-84. doi: 10.1049/iet-syb:20080116.

19.

Smad signaling dynamics: insights from a parsimonious model.

Shankaran H, Wiley HS.

Sci Signal. 2008 Sep 9;1(36):pe41. doi: 10.1126/scisignal.136pe41.

PMID:
18780891
20.

Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.

Shankaran H, Zhang Y, Opresko L, Resat H.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):220-4. doi: 10.1016/j.bbrc.2008.04.043. Epub 2008 Apr 18.

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