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Results: 1 to 20 of 29

1.

Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3.

Shankaran H, Zhang Y, Tan Y, Resat H.

PLoS Comput Biol. 2013;9(8):e1003201. doi: 10.1371/journal.pcbi.1003201. Epub 2013 Aug 22.

PMID:
23990774
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis.

von Neubeck C, Shankaran H, Geniza MJ, Kauer PM, Robinson RJ, Chrisler WB, Sowa MB.

Integr Biol (Camb). 2013 Oct;5(10):1229-43. doi: 10.1039/c3ib40071a.

PMID:
23925568
[PubMed - indexed for MEDLINE]
3.

Physiologically-based pharmacokinetic model for Fentanyl in support of the development of Provisional Advisory Levels.

Shankaran H, Adeshina F, Teeguarden JG.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):464-76. doi: 10.1016/j.taap.2013.05.024. Epub 2013 May 31.

PMID:
23732079
[PubMed - indexed for MEDLINE]
4.

Modeling dynamic regulatory processes in stroke.

McDermott JE, Jarman K, Taylor R, Lancaster M, Shankaran H, Vartanian KB, Stevens SL, Stenzel-Poore MP, Sanfilippo A.

PLoS Comput Biol. 2012;8(10):e1002722. doi: 10.1371/journal.pcbi.1002722. Epub 2012 Oct 11.

PMID:
23071432
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.

Shankaran H, Zhang Y, Chrisler WB, Ewald JA, Wiley HS, Resat H.

Mol Biosyst. 2012 Nov;8(11):2868-82. doi: 10.1039/c2mb25190f. Epub 2012 Sep 5.

PMID:
22952062
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Using imaging methods to interrogate radiation-induced cell signaling.

Shankaran H, Weber TJ, von Neubeck C, Sowa MB.

Radiat Res. 2012 Apr;177(4):496-507. Epub 2012 Mar 1. Review.

PMID:
22380462
[PubMed - indexed for MEDLINE]
7.

Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: implications for medical exposures.

von Neubeck C, Shankaran H, Karin NJ, Kauer PM, Chrisler WB, Wang X, Robinson RJ, Waters KM, Tilton SC, Sowa MB.

Environ Mol Mutagen. 2012 May;53(4):247-59. doi: 10.1002/em.21682. Epub 2012 Feb 20.

PMID:
22351304
[PubMed - indexed for MEDLINE]
8.

Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems.

McDermott JE, Shankaran H, Eisfeld AJ, Belisle SE, Neuman G, Li C, McWeeney S, Sabourin C, Kawaoka Y, Katze MG, Waters KM.

BMC Syst Biol. 2011 Nov 11;5:190. doi: 10.1186/1752-0509-5-190.

PMID:
22074594
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species.

Shankaran H, Chrisler WB, Sontag RL, Weber TJ.

Mol Carcinog. 2011 Jun;50(6):424-32. doi: 10.1002/mc.20724. Epub 2010 Dec 28.

PMID:
21557328
[PubMed - indexed for MEDLINE]
10.

Spatial aspects in biological system simulations.

Resat H, Costa MN, Shankaran H.

Methods Enzymol. 2011;487:485-511. doi: 10.1016/B978-0-12-381270-4.00017-2.

PMID:
21187236
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Oscillatory dynamics of the extracellular signal-regulated kinase pathway.

Shankaran H, Wiley HS.

Curr Opin Genet Dev. 2010 Dec;20(6):650-5. doi: 10.1016/j.gde.2010.08.002. Review.

PMID:
20810275
[PubMed - indexed for MEDLINE]
12.

Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.

Joslin EJ, Shankaran H, Opresko LK, Bollinger N, Lauffenburger DA, Wiley HS.

Mol Biosyst. 2010 Jul;6(7):1293-306. doi: 10.1039/c003921g. Epub 2010 May 10.

PMID:
20458382
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.

Weber TJ, Shankaran H, Wiley HS, Opresko LK, Chrisler WB, Quesenberry RD.

J Invest Dermatol. 2010 May;130(5):1444-56. doi: 10.1038/jid.2009.383. Epub 2009 Dec 17.

PMID:
20016498
[PubMed - indexed for MEDLINE]
Free Article
14.

Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.

Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS.

Mol Syst Biol. 2009;5:332. doi: 10.1038/msb.2009.90. Epub 2009 Dec 1.

PMID:
19953086
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.

Zhang Y, Opresko L, Shankaran H, Chrisler WB, Wiley HS, Resat H.

BMC Cell Biol. 2009 Oct 31;10:78. doi: 10.1186/1471-2121-10-78.

PMID:
19878579
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

System theoretical investigation of human epidermal growth factor receptor-mediated signalling.

Zhang Y, Shankaran H, Opresko L, Resat H.

IET Syst Biol. 2008 Sep;2(5):273-84. doi: 10.1049/iet-syb:20080116.

PMID:
19045822
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Smad signaling dynamics: insights from a parsimonious model.

Shankaran H, Wiley HS.

Sci Signal. 2008 Sep 9;1(36):pe41. doi: 10.1126/scisignal.136pe41.

PMID:
18780891
[PubMed - indexed for MEDLINE]
18.

Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.

Shankaran H, Zhang Y, Opresko L, Resat H.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):220-4. doi: 10.1016/j.bbrc.2008.04.043. Epub 2008 Apr 18.

PMID:
18424261
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Receptor downregulation and desensitization enhance the information processing ability of signalling receptors.

Shankaran H, Wiley HS, Resat H.

BMC Syst Biol. 2007 Nov 9;1:48.

PMID:
17996096
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cell surface receptors for signal transduction and ligand transport: a design principles study.

Shankaran H, Resat H, Wiley HS.

PLoS Comput Biol. 2007 Jun;3(6):e101. Epub 2007 Apr 20. Review.

PMID:
17542642
[PubMed - indexed for MEDLINE]
Free PMC Article

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