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Enzyme inhibition by allosteric capture of an inactive conformation.
J Mol Biol. 2011 Sep 2;411(5):999-1016. doi: 10.1016/j.jmb.2011.06.032. Epub 2011 Jun 22.
J Mol Biol. 2011.
PMID: 21723875
Free PMC article.
Inhibition of a viral enzyme by a small-molecule dimer disruptor.
Shahian T, Lee GM, Lazic A, Arnold LA, Velusamy P, Roels CM, Guy RK, Craik CS.
Shahian T, et al.
Nat Chem Biol. 2009 Sep;5(9):640-6. doi: 10.1038/nchembio.192. Epub 2009 Jul 26.
Nat Chem Biol. 2009.
PMID: 19633659
Free PMC article.
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Analysis of changes in nucleosome conformation using fluorescence resonance energy transfer.
Shahian T, Narlikar GJ.
Shahian T, et al.
Methods Mol Biol. 2012;833:337-49. doi: 10.1007/978-1-61779-477-3_20.
Methods Mol Biol. 2012.
PMID: 22183603
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A screening strategy for trapping the inactive conformer of a dimeric enzyme with a small molecule inhibitor.
Craik CS, Shahian T.
Craik CS, et al. Among authors: shahian t.
Methods Mol Biol. 2012;928:119-31. doi: 10.1007/978-1-62703-008-3_9.
Methods Mol Biol. 2012.
PMID: 22956137
Free PMC article.
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