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Results: 1 to 20 of 170

1.

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer.

Meidenbauer JJ, Mukherjee P, Seyfried TN.

Nutr Metab (Lond). 2015 Mar 11;12:12. doi: 10.1186/s12986-015-0009-2. eCollection 2015.

2.

Bis(monoacylglycero)phosphate: A secondary storage lipid in the gangliosidoses.

Akgoc Z, Sena-Esteves M, Martin DR, Han X, d'Azzo A, Seyfried TN.

J Lipid Res. 2015 Mar 20. pii: jlr.M057851. [Epub ahead of print]

3.

Myelin abnormalities in the optic and sciatic nerves in mice with GM1-gangliosidosis.

Heinecke KA, Luoma A, d'Azzo A, Kirschner DA, Seyfried TN.

ASN Neuro. 2015 Feb 18;7(1). pii: 1759091415568913. doi: 10.1177/1759091415568913. Print 2015 Jan-Feb.

4.

Widespread correction of central nervous system disease after intracranial gene therapy in a feline model of Sandhoff disease.

McCurdy VJ, Rockwell HE, Arthur JR, Bradbury AM, Johnson AK, Randle AN, Brunson BL, Hwang M, Gray-Edwards HL, Morrison NE, Johnson JA, Baker HJ, Cox NR, Seyfried TN, Sena-Esteves M, Martin DR.

Gene Ther. 2015 Feb;22(2):181-9. doi: 10.1038/gt.2014.108. Epub 2014 Dec 4.

PMID:
25474439
5.

Meal frequency and timing in health and disease.

Mattson MP, Allison DB, Fontana L, Harvie M, Longo VD, Malaisse WJ, Mosley M, Notterpek L, Ravussin E, Scheer FA, Seyfried TN, Varady KA, Panda S.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16647-53. doi: 10.1073/pnas.1413965111. Epub 2014 Nov 17.

PMID:
25404320
6.

Ganglioside storage diseases: on the road to management.

Seyfried TN, Rockwell HE, Heinecke KA, Martin DR, Sena-Esteves M.

Adv Neurobiol. 2014;9:485-99. doi: 10.1007/978-1-4939-1154-7_22.

PMID:
25151393
7.

Metabolic therapy: a new paradigm for managing malignant brain cancer.

Seyfried TN, Flores R, Poff AM, D'Agostino DP, Mukherjee P.

Cancer Lett. 2015 Jan 28;356(2 Pt A):289-300. doi: 10.1016/j.canlet.2014.07.015. Epub 2014 Jul 25. Review.

PMID:
25069036
8.

Ketone strong: emerging evidence for a therapeutic role of ketone bodies in neurological and neurodegenerative diseases.

Seyfried TN.

J Lipid Res. 2014 Sep;55(9):1815-7. doi: 10.1194/jlr.E052944. Epub 2014 Jul 11. No abstract available.

PMID:
25015970
9.

Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice.

Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN.

Epilepsy Res. 2014 Sep;108(7):1137-44. doi: 10.1016/j.eplepsyres.2014.05.010. Epub 2014 Jun 2.

PMID:
24938543
10.

Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice.

Meidenbauer JJ, Ta N, Seyfried TN.

Nutr Metab (Lond). 2014 May 22;11:23. doi: 10.1186/1743-7075-11-23. eCollection 2014.

11.

Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer.

Poff AM, Ari C, Arnold P, Seyfried TN, D'Agostino DP.

Int J Cancer. 2014 Oct 1;135(7):1711-20. doi: 10.1002/ijc.28809. Epub 2014 May 14.

12.

Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation.

Dufort FJ, Gumina MR, Ta NL, Tao Y, Heyse SA, Scott DA, Richardson AD, Seyfried TN, Chiles TC.

J Biol Chem. 2014 Mar 7;289(10):7011-24. doi: 10.1074/jbc.M114.551051. Epub 2014 Jan 27.

13.

Cancer as a metabolic disease: implications for novel therapeutics.

Seyfried TN, Flores RE, Poff AM, D'Agostino DP.

Carcinogenesis. 2014 Mar;35(3):515-27. doi: 10.1093/carcin/bgt480. Epub 2013 Dec 16. Review.

14.

Autosomal dominant inheritance of brain cardiolipin fatty acid abnormality in VM/DK mice: association with hypoxic-induced cognitive insensitivity.

Ta NL, Jia X, Kiebish M, Seyfried TN.

Lipids. 2014 Jan;49(1):113-7. doi: 10.1007/s11745-013-3857-4. Epub 2013 Nov 16.

PMID:
24243001
15.

A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.

Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, Matalon R, Gao G.

Mol Ther. 2013 Dec;21(12):2136-47. doi: 10.1038/mt.2013.138. Epub 2013 Jul 2.

16.

The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.

Poff AM, Ari C, Seyfried TN, D'Agostino DP.

PLoS One. 2013 Jun 5;8(6):e65522. doi: 10.1371/journal.pone.0065522. Print 2013.

17.

Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy.

Bradbury AM, Cochran JN, McCurdy VJ, Johnson AK, Brunson BL, Gray-Edwards H, Leroy SG, Hwang M, Randle AN, Jackson LS, Morrison NE, Baek RC, Seyfried TN, Cheng SH, Cox NR, Baker HJ, Cachón-González MB, Cox TM, Sena-Esteves M, Martin DR.

Mol Ther. 2013 Jul;21(7):1306-15. doi: 10.1038/mt.2013.86. Epub 2013 May 21.

18.

Ethylenedioxy-PIP2 oxalate reduces ganglioside storage in juvenile Sandhoff disease mice.

Arthur JR, Wilson MW, Larsen SD, Rockwell HE, Shayman JA, Seyfried TN.

Neurochem Res. 2013 Apr;38(4):866-75. doi: 10.1007/s11064-013-0992-5. Epub 2013 Feb 16.

PMID:
23417430
19.

On the origin of cancer metastasis.

Seyfried TN, Huysentruyt LC.

Crit Rev Oncog. 2013;18(1-2):43-73. Review.

20.

Therapeutic effects of stem cells and substrate reduction in juvenile Sandhoff mice.

Arthur JR, Lee JP, Snyder EY, Seyfried TN.

Neurochem Res. 2012 Jun;37(6):1335-43. doi: 10.1007/s11064-012-0718-0. Epub 2012 Feb 25.

PMID:
22367451
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