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Results: 1 to 20 of 45


Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potential.

Welch JD, Baran-Gale J, Perou CM, Sethupathy P, Prins JF.

BMC Genomics. 2015 Feb 22;16(1):113.


Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.

Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P.

Sci Rep. 2015 Jan 8;5:7675. doi: 10.1038/srep07675.


Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

Franceschini N, Hu Y, Reiner AP, Buyske S, Nalls M, Yanek LR, Li Y, Hindorff LA, Cole SA, Howard BV, Stafford JM, Carty CL, Sethupathy P, Martin LW, Lin DY, Johnson KC, Becker LC, North KE, Dehghan A, Bis JC, Liu Y, Greenland P, Manson JE, Maeda N, Garcia M, Harris TB, Becker DM, O'Donnell C, Heiss G, Kooperberg C, Boerwinkle E.

PLoS One. 2014 Dec 26;9(12):e113203. doi: 10.1371/journal.pone.0113203. eCollection 2014.


MicroRNA-223 coordinates cholesterol homeostasis.

Vickers KC, Landstreet SR, Levin MG, Shoucri BM, Toth CL, Taylor RC, Palmisano BT, Tabet F, Cui HL, Rye KA, Sethupathy P, Remaley AT.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14518-23. doi: 10.1073/pnas.1215767111. Epub 2014 Sep 22.


An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.

Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ.

BMC Genomics. 2014 Aug 25;15:711. doi: 10.1186/1471-2164-15-711.


Transcriptional targets of the schizophrenia risk gene MIR137.

Collins AL, Kim Y, Bloom RJ, Kelada SN, Sethupathy P, Sullivan PF.

Transl Psychiatry. 2014 Jul 1;4:e404. doi: 10.1038/tp.2014.42.


MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.

Kurtz CL, Peck BC, Fannin EE, Beysen C, Miao J, Landstreet SR, Ding S, Turaga V, Lund PK, Turner S, Biddinger SB, Vickers KC, Sethupathy P.

Diabetes. 2014 Sep;63(9):3141-8. doi: 10.2337/db13-1015. Epub 2014 Apr 10.


HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells.

Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, Catherinet C, Prado-Lourenco L, Levin MG, Thacker S, Sethupathy P, Barter PJ, Remaley AT, Rye KA.

Nat Commun. 2014 Feb 28;5:3292. doi: 10.1038/ncomms4292.


Genetics. Genetics driving epigenetics.

Furey TS, Sethupathy P.

Science. 2013 Nov 8;342(6159):705-6. doi: 10.1126/science.1246755. No abstract available.


Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes.

Baran-Gale J, Fannin EE, Kurtz CL, Sethupathy P.

PLoS One. 2013 Sep 9;8(9):e73240. doi: 10.1371/journal.pone.0073240. eCollection 2013.


Illuminating microRNA Transcription from the Epigenome.

Sethupathy P.

Curr Genomics. 2013 Mar;14(1):68-77. doi: 10.2174/138920213804999183.


miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation.

Kelada S, Sethupathy P, Okoye IS, Kistasis E, Czieso S, White SD, Chou D, Martens C, Ricklefs SM, Virtaneva K, Sturdevant DE, Porcella SF, Belkaid Y, Wynn TA, Wilson MS.

PLoS Pathog. 2013;9(6):e1003451. doi: 10.1371/journal.ppat.1003451. Epub 2013 Jun 27.


A model of electrophysiological heterogeneity in periglomerular cells.

Sethupathy P, Rubin DB, Li G, Cleland TA.

Front Comput Neurosci. 2013 Apr 26;7:49. doi: 10.3389/fncom.2013.00049. eCollection 2013.


Prioritization of genetic variants in the microRNA regulome as functional candidates in genome-wide association studies.

Bulik-Sullivan B, Selitsky S, Sethupathy P.

Hum Mutat. 2013 Aug;34(8):1049-56. doi: 10.1002/humu.22337. Epub 2013 May 8.


Complexity of microRNA function and the role of isomiRs in lipid homeostasis.

Vickers KC, Sethupathy P, Baran-Gale J, Remaley AT.

J Lipid Res. 2013 May;54(5):1182-91. doi: 10.1194/jlr.R034801. Epub 2013 Mar 15. Review.


Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome.

Sethupathy P.

J Lipid Res. 2013 May;54(5):1168-73. doi: 10.1194/jlr.R035766. Epub 2013 Mar 15. Review.


A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, Monda K, Ehret G, Nguyen KD, Cooper R, Lewis CE, Leppert M, Irvin MR, Gu CC, Houston D, Buzkova P, Ritchie M, Matise TC, Le Marchand L, Hindorff LA, Crawford DC, Haiman CA, Kooperberg C.

PLoS Genet. 2013;9(1):e1003171. doi: 10.1371/journal.pgen.1003171. Epub 2013 Jan 17.


Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index.

Paredes SH, Melgar MF, Sethupathy P.

Bioinformatics. 2013 Jun 15;29(12):1485-7. doi: 10.1093/bioinformatics/bts596. Epub 2012 Oct 9.


Fine-mapping and initial characterization of QT interval loci in African Americans.

Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, Sotoodehnia N, Young AM, Kooperberg C, Haiman CA, Mohlke KL, Whitsel EA, North KE.

PLoS Genet. 2012;8(8):e1002870. doi: 10.1371/journal.pgen.1002870. Epub 2012 Aug 9.


MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia.

Vickers KC, Shoucri BM, Levin MG, Wu H, Pearson DS, Osei-Hwedieh D, Collins FS, Remaley AT, Sethupathy P.

Hepatology. 2013 Feb;57(2):533-42. doi: 10.1002/hep.25846. Epub 2012 Jul 6.

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