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Items: 1 to 20 of 91


β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4.

Funa NS, Schachter KA, Lerdrup M, Ekberg J, Hess K, Dietrich N, Honoré C, Hansen K, Semb H.

Cell Stem Cell. 2015 Jun 4;16(6):639-52. doi: 10.1016/j.stem.2015.03.008. Epub 2015 Apr 23.


Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.

Kesavan G, Lieven O, Mamidi A, Öhlin ZL, Johansson JK, Li WC, Lommel S, Greiner TU, Semb H.

Development. 2014 Feb;141(3):685-96. doi: 10.1242/dev.100297.


Artificial three-dimensional niches deconstruct pancreas development in vitro.

Greggio C, De Franceschi F, Figueiredo-Larsen M, Gobaa S, Ranga A, Semb H, Lutolf M, Grapin-Botton A.

Development. 2013 Nov;140(21):4452-62. doi: 10.1242/dev.096628.


Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28.

Hernebring M, Fredriksson Å, Liljevald M, Cvijovic M, Norrman K, Wiseman J, Semb H, Nyström T.

Sci Rep. 2013;3:1381. doi: 10.1038/srep01381.


Distinct gene expression signatures in human embryonic stem cells differentiated towards definitive endoderm at single-cell level.

Norrman K, Strömbeck A, Semb H, Ståhlberg A.

Methods. 2013 Jan;59(1):59-70. doi: 10.1016/j.ymeth.2012.03.030. Epub 2012 Apr 5.


N-CAM exhibits a regulatory function in pathological angiogenesis in oxygen induced retinopathy.

Håkansson J, Ståhlberg A, Wolfhagen Sand F, Gerhardt H, Semb H.

PLoS One. 2011;6(10):e26026. doi: 10.1371/journal.pone.0026026. Epub 2011 Oct 17.


Growth-limiting role of endothelial cells in endoderm development.

Sand FW, Hörnblad A, Johansson JK, Lorén C, Edsbagge J, Ståhlberg A, Magenheim J, Ilovich O, Mishani E, Dor Y, Ahlgren U, Semb H.

Dev Biol. 2011 Apr 15;352(2):267-77. doi: 10.1016/j.ydbio.2011.01.026. Epub 2011 Jan 31.


Quantitative comparison of constitutive promoters in human ES cells.

Norrman K, Fischer Y, Bonnamy B, Wolfhagen Sand F, Ravassard P, Semb H.

PLoS One. 2010 Aug 26;5(8):e12413. doi: 10.1371/journal.pone.0012413.


NANOG reporter cell lines generated by gene targeting in human embryonic stem cells.

Fischer Y, Ganic E, Ameri J, Xian X, Johannesson M, Semb H.

PLoS One. 2010 Sep 2;5(9). pii: e12533. doi: 10.1371/journal.pone.0012533.


N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover.

Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H.

Genesis. 2010 Jun;48(6):374-81. doi: 10.1002/dvg.20628.


The establishment of 20 different human embryonic stem cell lines and subclones; a report on derivation, culture, characterisation and banking.

Englund MC, Caisander G, Noaksson K, Emanuelsson K, Lundin K, Bergh C, Hansson C, Semb H, Strehl R, Hyllner J.

In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):217-30. doi: 10.1007/s11626-010-9289-z. Epub 2010 Feb 23.


Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia.

Olivecrona G, Ehrenborg E, Semb H, Makoveichuk E, Lindberg A, Hayden MR, Gin P, Davies BS, Weinstein MM, Fong LG, Beigneux AP, Young SG, Olivecrona T, Hernell O.

J Lipid Res. 2010 Jun;51(6):1535-45. doi: 10.1194/jlr.M002717. Epub 2009 Dec 21.


Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage.

Brolén G, Sivertsson L, Björquist P, Eriksson G, Ek M, Semb H, Johansson I, Andersson TB, Ingelman-Sundberg M, Heins N.

J Biotechnol. 2010 Feb 1;145(3):284-94. doi: 10.1016/j.jbiotec.2009.11.007. Epub 2009 Nov 20.


Cdc42-mediated tubulogenesis controls cell specification.

Kesavan G, Sand FW, Greiner TU, Johansson JK, Kobberup S, Wu X, Brakebusch C, Semb H.

Cell. 2009 Nov 13;139(4):791-801. doi: 10.1016/j.cell.2009.08.049.


FGF2 specifies hESC-derived definitive endoderm into foregut/midgut cell lineages in a concentration-dependent manner.

Ameri J, Ståhlberg A, Pedersen J, Johansson JK, Johannesson MM, Artner I, Semb H.

Stem Cells. 2010 Jan;28(1):45-56. doi: 10.1002/stem.249.


Quantitative transcription factor analysis of undifferentiated single human embryonic stem cells.

Ståhlberg A, Bengtsson M, Hemberg M, Semb H.

Clin Chem. 2009 Dec;55(12):2162-70. doi: 10.1373/clinchem.2009.131433. Epub 2009 Oct 8.


FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.

Johannesson M, Ståhlberg A, Ameri J, Sand FW, Norrman K, Semb H.

PLoS One. 2009;4(3):e4794. doi: 10.1371/journal.pone.0004794. Epub 2009 Mar 11.


Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.

Olofsson CS, Håkansson J, Salehi A, Bengtsson M, Galvanovskis J, Partridge C, SörhedeWinzell M, Xian X, Eliasson L, Lundquist I, Semb H, Rorsman P.

Endocrinology. 2009 Jul;150(7):3067-75. doi: 10.1210/en.2008-0475. Epub 2009 Feb 12.


Rac1 regulates pancreatic islet morphogenesis.

Greiner TU, Kesavan G, Ståhlberg A, Semb H.

BMC Dev Biol. 2009 Jan 6;9:2. doi: 10.1186/1471-213X-9-2.


Expandable endodermal progenitors: new tools to explore endoderm and its derivatives.

Semb H.

Cell Stem Cell. 2008 Oct 9;3(4):355-6. doi: 10.1016/j.stem.2008.09.010.

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