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Results: 1 to 20 of 145

1.

ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development.

Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, Zhong Z, Valasek MA, Seki E, Hidalgo J, Koike K, Kaufman RJ, Karin M.

Cancer Cell. 2014 Aug 12. pii: S1535-6108(14)00277-3. doi: 10.1016/j.ccr.2014.07.001. [Epub ahead of print]

PMID:
25132496
[PubMed - as supplied by publisher]
2.

Hepatic Inflammation and Fibrosis: Functional Links and Key Pathways.

Seki E, Schwabe RF.

Hepatology. 2014 Jul 26. doi: 10.1002/hep.27332. [Epub ahead of print]

PMID:
25066777
[PubMed - as supplied by publisher]
3.

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P.

Nat Commun. 2014 Jul 21;5:4451. doi: 10.1038/ncomms5451.

PMID:
25043713
[PubMed - in process]
4.

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.

Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E.

J Clin Invest. 2014 Aug 1;124(8):3566-78. doi: 10.1172/JCI74068. Epub 2014 Jul 1.

PMID:
24983318
[PubMed - in process]
Free PMC Article
5.

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.

Umemura A, Park EJ, Taniguchi K, Lee JH, Shalapour S, Valasek MA, Aghajan M, Nakagawa H, Seki E, Hall MN, Karin M.

Cell Metab. 2014 Jul 1;20(1):133-44. doi: 10.1016/j.cmet.2014.05.001. Epub 2014 Jun 5.

PMID:
24910242
[PubMed - in process]
6.

Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo.

Liang S, Zhong Z, Seki E.

Gastroenterology. 2014 Jun;146(7):1823-5. doi: 10.1053/j.gastro.2014.04.010. Epub 2014 Apr 21. No abstract available.

PMID:
24768331
[PubMed - indexed for MEDLINE]
7.

Microbiome-obesity-liver cancer interaction: senescence of hepatic stellate cells and bile acids play new roles.

Seki E.

Gastroenterology. 2014 Mar;146(3):860-1. doi: 10.1053/j.gastro.2014.01.029. Epub 2014 Jan 24. No abstract available.

PMID:
24468171
[PubMed - indexed for MEDLINE]
8.

Transcriptional repression of the transforming growth factor β (TGF-β) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor κB (NF-κB) p50 enhances TGF-β signaling in hepatic stellate cells.

Liu C, Chen X, Yang L, Kisseleva T, Brenner DA, Seki E.

J Biol Chem. 2014 Mar 7;289(10):7082-91. doi: 10.1074/jbc.M113.543769. Epub 2014 Jan 21.

PMID:
24448807
[PubMed - indexed for MEDLINE]
9.

Reply.

Yang L, Seki E.

Hepatology. 2014 Jan 17. doi: 10.1002/hep.27019. [Epub ahead of print] No abstract available.

PMID:
24443149
[PubMed - as supplied by publisher]
10.

TAK1 regulates hepatic cell survival and carcinogenesis.

Roh YS, Song J, Seki E.

J Gastroenterol. 2014 Feb;49(2):185-94. doi: 10.1007/s00535-013-0931-x. Epub 2014 Jan 21.

PMID:
24443058
[PubMed - in process]
11.

NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet.

Dhar D, Seki E, Karin M.

Cell Metab. 2014 Jan 7;19(1):6-7. doi: 10.1016/j.cmet.2013.12.010.

PMID:
24411937
[PubMed - indexed for MEDLINE]
12.

Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis.

Roh YS, Park S, Kim JW, Lim CW, Seki E, Kim B.

Hepatology. 2014 Jul;60(1):237-49. doi: 10.1002/hep.26981. Epub 2014 May 27.

PMID:
24375615
[PubMed - in process]
13.

Nrf2 activation protects the liver from ischemia/reperfusion injury in mice.

Kudoh K, Uchinami H, Yoshioka M, Seki E, Yamamoto Y.

Ann Surg. 2014 Jul;260(1):118-27. doi: 10.1097/SLA.0000000000000287.

PMID:
24368646
[PubMed - indexed for MEDLINE]
14.

Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls.

Patel NS, Peterson MR, Lin GY, Feldstein A, Schnabl B, Bettencourt R, Seki E, Sirlin CB, Loomba R.

Gastroenterol Res Pract. 2013;2013:498296. doi: 10.1155/2013/498296. Epub 2013 Nov 17.

PMID:
24348536
[PubMed]
Free PMC Article
15.

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse.

Moles A, Murphy L, Wilson CL, Chakraborty JB, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA.

J Hepatol. 2014 Apr;60(4):782-91. doi: 10.1016/j.jhep.2013.12.005. Epub 2013 Dec 11.

PMID:
24333183
[PubMed - in process]
Free PMC Article
16.

Inhibitory effect of tacrolimus on progression of joint damage in patients with rheumatoid arthritis.

Motomura H, Matsushita I, Seki E, Mine H, Kimura T.

Int J Rheum Dis. 2013 Nov 20. doi: 10.1111/1756-185X.12227. [Epub ahead of print]

PMID:
24251619
[PubMed - as supplied by publisher]
17.

Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling.

He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, Hoffman RM, Tateishi R, Koike K, Karin M.

Cell. 2013 Oct 10;155(2):384-96. doi: 10.1016/j.cell.2013.09.031.

PMID:
24120137
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice.

Yang L, Roh YS, Song J, Zhang B, Liu C, Loomba R, Seki E.

Hepatology. 2014 Feb;59(2):483-95. doi: 10.1002/hep.26698. Epub 2013 Dec 18.

PMID:
23996730
[PubMed - indexed for MEDLINE]
19.

Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis.

Roh YS, Seki E.

J Gastroenterol Hepatol. 2013 Aug;28 Suppl 1:38-42. doi: 10.1111/jgh.12019. Review.

PMID:
23855294
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Dislocation of the extensor carpi ulnaris tendon in rheumatoid wrists using three-dimensional computed tomographic imaging.

Seki E, Ishikawa H, Murasawa A, Nakazono K, Abe A, Horizono H, Ishii K.

Clin Rheumatol. 2013 Nov;32(11):1627-32. doi: 10.1007/s10067-013-2331-2. Epub 2013 Jul 16.

PMID:
23857663
[PubMed - indexed for MEDLINE]

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