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Items: 1 to 20 of 139


Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice.

Yu Q, Liu X, Liu Y, Riederer B, Li T, Tian DA, Tuo B, Shull G, Seidler U.

Pflugers Arch. 2016 Aug;468(8):1419-32. doi: 10.1007/s00424-016-1836-3. Epub 2016 May 26.


Clinical Effects of a Topically Applied Toll-like Receptor 9 Agonist in Active Moderate-to-Severe Ulcerative Colitis.

Atreya R, Bloom S, Scaldaferri F, Gerardi V, Admyre C, Karlsson Å, Knittel T, Kowalski J, Lukas M, Löfberg R, Nancey S, Petryka R, Rydzewska G, Schnabel R, Seidler U, Neurath MF, Hawkey C.

J Crohns Colitis. 2016 May 20. pii: jjw103. [Epub ahead of print]


Host and microbiota interactions are critical for development of murine Crohn's-like ileitis.

Roulis M, Bongers G, Armaka M, Salviano T, He Z, Singh A, Seidler U, Becker C, Demengeot J, Furtado GC, Lira SA, Kollias G.

Mucosal Immunol. 2016 May;9(3):787-97. doi: 10.1038/mi.2015.102. Epub 2015 Oct 21.


Randomised clinical trial: vercirnon, an oral CCR9 antagonist, vs. placebo as induction therapy in active Crohn's disease.

Feagan BG, Sandborn WJ, D'Haens G, Lee SD, Allez M, Fedorak RN, Seidler U, Vermeire S, Lawrance IC, Maroney AC, Jurgensen CH, Heath A, Chang DJ.

Aliment Pharmacol Ther. 2015 Nov;42(10):1170-81. doi: 10.1111/apt.13398. Epub 2015 Sep 23.


Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.

Jalali R, Zandieh-Doulabi B, DenBesten PK, Seidler U, Riederer B, Wedenoja S, Micha D, Bronckers AL.

J Dent Res. 2015 Dec;94(12):1732-9. doi: 10.1177/0022034515606873. Epub 2015 Sep 22.


Evidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitis.

Yeruva S, Chodisetti G, Luo M, Chen M, Cinar A, Ludolph L, Lünnemann M, Goldstein J, Singh AK, Riederer B, Bachmann O, Bleich A, Gereke M, Bruder D, Hagen S, He P, Yun C, Seidler U.

Pflugers Arch. 2015 Aug;467(8):1795-807. doi: 10.1007/s00424-014-1608-x. Epub 2014 Oct 2.


Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO3(-) transport and reduces survival in CFTR-deficient mice.

Liu X, Li T, Riederer B, Lenzen H, Ludolph L, Yeruva S, Tuo B, Soleimani M, Seidler U.

Pflugers Arch. 2015 Jun;467(6):1261-75. doi: 10.1007/s00424-014-1543-x. Epub 2014 Jun 27.


An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

Kamiya K, Michel V, Giraudet F, Riederer B, Foucher I, Papal S, Perfettini I, Le Gal S, Verpy E, Xia W, Seidler U, Georgescu MM, Avan P, El-Amraoui A, Petit C.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9307-12. doi: 10.1073/pnas.1405322111. Epub 2014 Jun 11.


Short-term regulation of murine colonic NBCe1-B (electrogenic Na+/HCO3(-) cotransporter) membrane expression and activity by protein kinase C.

May O, Yu H, Riederer B, Manns MP, Seidler U, Bachmann O.

PLoS One. 2014 Mar 18;9(3):e92275. doi: 10.1371/journal.pone.0092275. eCollection 2014.


Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1.

Rubino R, Bezzerri V, Favia M, Facchini M, Tebon M, Singh AK, Riederer B, Seidler U, Iannucci A, Bragonzi A, Cabrini G, Reshkin SJ, Tamanini A.

Pflugers Arch. 2014 Dec;466(12):2269-78. doi: 10.1007/s00424-014-1474-6. Epub 2014 Mar 5.


Na⁺/H⁺ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney.

Park J, Kwak JO, Riederer B, Seidler U, Cole SP, Lee HJ, Lee MG.

J Am Soc Nephrol. 2014 Apr;25(4):726-36. doi: 10.1681/ASN.2013040438. Epub 2014 Jan 16.


Slc26a3 deficiency is associated with loss of colonic HCO3 (-) secretion, absence of a firm mucus layer and barrier impairment in mice.

Xiao F, Yu Q, Li J, Johansson ME, Singh AK, Xia W, Riederer B, Engelhardt R, Montrose M, Soleimani M, Tian DA, Xu G, Hansson GC, Seidler U.

Acta Physiol (Oxf). 2014 May;211(1):161-75. doi: 10.1111/apha.12220. Epub 2014 Jan 31.


The role of pancreatic ductal secretion in protection against acute pancreatitis in mice*.

Pallagi P, Balla Z, Singh AK, Dósa S, Iványi B, Kukor Z, Tóth A, Riederer B, Liu Y, Engelhardt R, Jármay K, Szabó A, Janovszky A, Perides G, Venglovecz V, Maléth J, Wittmann T, Takács T, Gray MA, Gácser A, Hegyi P, Seidler U, Rakonczay Z Jr.

Crit Care Med. 2014 Mar;42(3):e177-88. doi: 10.1097/CCM.0000000000000101.


Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3.

Sultan A, Luo M, Yu Q, Riederer B, Xia W, Chen M, Lissner S, Gessner JE, Donowitz M, Yun CC, deJonge H, Lamprecht G, Seidler U.

Cell Physiol Biochem. 2013;32(5):1386-402.


Gastrointestinal HCO3- transport and epithelial protection in the gut: new techniques, transport pathways and regulatory pathways.

Seidler UE.

Curr Opin Pharmacol. 2013 Dec;13(6):900-8. doi: 10.1016/j.coph.2013.10.001. Epub 2013 Oct 25. Review.


The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.

Xia W, Yu Q, Riederer B, Singh AK, Engelhardt R, Yeruva S, Song P, Tian DA, Soleiman M, Seidler U.

Pflugers Arch. 2014 Aug;466(8):1541-56.


Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.

Singh AK, Liu Y, Riederer B, Engelhardt R, Thakur BK, Soleimani M, Seidler U.

J Physiol. 2013 Nov 1;591(21):5377-91. doi: 10.1113/jphysiol.2013.254854. Epub 2013 Sep 9.


The PDZ-interaction of the intestinal anion exchanger downregulated in adenoma (DRA; SLC26A3) facilitates its movement into Rab11a-positive recycling endosomes.

Lissner S, Hsieh CJ, Nold L, Bannert K, Bodammer P, Sultan A, Seidler U, Graeve L, Lamprecht G.

Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1;304(11):G980-90. doi: 10.1152/ajpgi.00132.2012. Epub 2013 Apr 11.


Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.

Juric M, Xiao F, Amasheh S, May O, Wahl K, Bantel H, Manns MP, Seidler U, Bachmann O.

Inflamm Bowel Dis. 2013 Apr;19(5):904-11. doi: 10.1097/MIB.0b013e3182813322.

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