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Results: 1 to 20 of 46

1.

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma.

Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, Unterberg A, Hartmann C, Pietsch T, Reifenberger G, Lichter P, Radlwimmer B, Platten M, Pfister SM, von Deimling A, Weller M, Wick W.

Acta Neuropathol. 2014 Jul 10. [Epub ahead of print]

PMID:
25008768
[PubMed - as supplied by publisher]
2.

Extramedullary relapse after accidental head injury in a patient with multiple myeloma.

Merz M, Schweizer L, Kentar M, Schneider T, Goldschmidt H, Hillengass J.

Ann Hematol. 2014 Jun 29. [Epub ahead of print] No abstract available.

PMID:
24974108
[PubMed - as supplied by publisher]
3.

Nuclear relocation of STAT6 reliably predicts NAB2/STAT6 fusion for the diagnosis of Solitary Fibrous Tumour.

Koelsche C, Schweizer L, Renner M, Warth A, Jones DT, Sahm F, Reuss DE, Capper D, Knösel T, Schulz B, Petersen I, Ulrich A, Renker EK, Lehner B, Pfister SM, Schirmacher P, von Deimling A, Mechtersheimer G.

Histopathology. 2014 Apr 4. doi: 10.1111/his.12431. [Epub ahead of print]

PMID:
24702701
[PubMed - as supplied by publisher]
4.

Establishing a High-content Analysis Method for Tubulin Polymerization to Evaluate Both the Stabilizing and Destabilizing Activities of Compounds.

Sum CS, Nickischer D, Lei M, Weston A, Zhang L, Schweizer L.

Curr Chem Genomics Transl Med. 2014 Feb 7;8(Suppl 1):16-26. doi: 10.2174/2213988501408010016. eCollection 2014.

PMID:
24596681
[PubMed]
Free PMC Article
5.

Targeting epigenetic regulators for cancer therapy.

Wee S, Dhanak D, Li H, Armstrong SA, Copeland RA, Sims R, Baylin SB, Liu XS, Schweizer L.

Ann N Y Acad Sci. 2014 Feb;1309:30-6. doi: 10.1111/nyas.12356. Review.

PMID:
24571255
[PubMed - indexed for MEDLINE]
6.

D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma.

Pusch S, Schweizer L, Beck AC, Lehmler JM, Weissert S, Balss J, Miller AK, von Deimling A.

Acta Neuropathol Commun. 2014 Feb 14;2(1):19. doi: 10.1186/2051-5960-2-19.

PMID:
24529257
[PubMed]
Free PMC Article
7.

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.

Sahm F, Bissel J, Koelsche C, Schweizer L, Capper D, Reuss D, Böhmer K, Lass U, Göck T, Kalis K, Meyer J, Habel A, Brehmer S, Mittelbronn M, Jones DT, Schittenhelm J, Urbschat S, Ketter R, Heim S, Mawrin C, Hainfellner JA, Berghoff AS, Preusser M, Becker A, Herold-Mende C, Unterberg A, Hartmann C, Kickingereder P, Collins VP, Pfister SM, von Deimling A.

Acta Neuropathol. 2013 Nov;126(5):757-62. doi: 10.1007/s00401-013-1187-5. Epub 2013 Oct 6.

PMID:
24096618
[PubMed - indexed for MEDLINE]
8.

Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization.

Lei M, Ribeiro H, Kolodin G, Gill J, Wang YS, Maloney D, Fan Y, Li S, Myer L, Beluch M, Zhang L, Schweizer L.

J Biomol Screen. 2013 Oct;18(9):1043-53. doi: 10.1177/1087057113491825. Epub 2013 Jun 3.

PMID:
23733846
[PubMed - indexed for MEDLINE]
9.

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein.

Schweizer L, Koelsche C, Sahm F, Piro RM, Capper D, Reuss DE, Pusch S, Habel A, Meyer J, Göck T, Jones DT, Mawrin C, Schittenhelm J, Becker A, Heim S, Simon M, Herold-Mende C, Mechtersheimer G, Paulus W, König R, Wiestler OD, Pfister SM, von Deimling A.

Acta Neuropathol. 2013 May;125(5):651-8. doi: 10.1007/s00401-013-1117-6. Epub 2013 Apr 11.

PMID:
23575898
[PubMed - indexed for MEDLINE]
10.

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.

Reuss DE, Piro RM, Jones DT, Simon M, Ketter R, Kool M, Becker A, Sahm F, Pusch S, Meyer J, Hagenlocher C, Schweizer L, Capper D, Kickingereder P, Mucha J, Koelsche C, Jäger N, Santarius T, Tarpey PS, Stephens PJ, Andrew Futreal P, Wellenreuther R, Kraus J, Lenartz D, Herold-Mende C, Hartmann C, Mawrin C, Giese N, Eils R, Collins VP, König R, Wiestler OD, Pfister SM, von Deimling A.

Acta Neuropathol. 2013 Mar;125(3):351-8. doi: 10.1007/s00401-013-1093-x. Epub 2013 Feb 12.

PMID:
23404370
[PubMed - indexed for MEDLINE]
11.

The contribution of the nonhomologous region of Prs1 to the maintenance of cell wall integrity and cell viability.

Ugbogu EA, Wippler S, Euston M, Kouwenhoven EN, de Brouwer AP, Schweizer LM, Schweizer M.

FEMS Yeast Res. 2013 May;13(3):291-301. doi: 10.1111/1567-1364.12033. Epub 2013 Mar 13.

PMID:
23368839
[PubMed - indexed for MEDLINE]
12.

Enhancing Cancer Drug Discovery through Novel Cell Signaling Pathway Panel Strategy.

Schweizer L, Zhang L.

Cancer Growth Metastasis. 2013 Aug 20;6:53-9. doi: 10.4137/CGM.S11134. eCollection 2013.

PMID:
24665207
[PubMed]
Free PMC Article
13.

Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors.

Shi Y, O'Connor SP, Sitkoff D, Zhang J, Shi M, Bisaha SN, Wang Y, Li C, Ruan Z, Lawrence RM, Klei HE, Kish K, Liu EC, Seiler SM, Schweizer L, Steinbacher TE, Schumacher WA, Robl JA, Macor JE, Atwal KS, Stein PD.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7516-21. doi: 10.1016/j.bmcl.2011.06.098. Epub 2011 Jun 28.

PMID:
22041058
[PubMed - indexed for MEDLINE]
14.

SDRS--an algorithm for analyzing large-scale dose-response data.

Ji RR, Siemers NO, Lei M, Schweizer L, Bruccoleri RE.

Bioinformatics. 2011 Oct 15;27(20):2921-3. doi: 10.1093/bioinformatics/btr489. Epub 2011 Aug 24.

PMID:
21865301
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0(2,6)]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists.

Xiao HY, Balog A, Attar RM, Fairfax D, Fleming LB, Holst CL, Martin GS, Rossiter LM, Chen J, Cvjic ME, Dell-John J, Geng J, Gottardis MM, Han WC, Nation A, Obermeier M, Rizzo CA, Schweizer L, Spires T Jr, Shan W, Gavai A, Salvati ME, Vite G.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4491-5. doi: 10.1016/j.bmcl.2010.06.034. Epub 2010 Jun 10.

PMID:
20584610
[PubMed - indexed for MEDLINE]
16.

Valproic acid- and lithium-sensitivity in prs mutants of Saccharomyces cerevisiae.

Kleineidam A, Vavassori S, Wang K, Schweizer LM, Griac P, Schweizer M.

Biochem Soc Trans. 2009 Oct;37(Pt 5):1115-20. doi: 10.1042/BST0371115.

PMID:
19754463
[PubMed - indexed for MEDLINE]
17.

Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer.

Attar RM, Jure-Kunkel M, Balog A, Cvijic ME, Dell-John J, Rizzo CA, Schweizer L, Spires TE, Platero JS, Obermeier M, Shan W, Salvati ME, Foster WR, Dinchuk J, Chen SJ, Vite G, Kramer R, Gottardis MM.

Cancer Res. 2009 Aug 15;69(16):6522-30. doi: 10.1158/0008-5472.CAN-09-1111. Epub 2009 Aug 4.

PMID:
19654297
[PubMed - indexed for MEDLINE]
Free Article
18.

The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens.

Schweizer L, Rizzo CA, Spires TE, Platero JS, Wu Q, Lin TA, Gottardis MM, Attar RM.

BMC Cell Biol. 2008 Jan 24;9:4. doi: 10.1186/1471-2121-9-4.

PMID:
18218096
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Yeast-based assay for the measurement of positive and negative influences on microsatellite stability.

Marden A, Walmsley RM, Schweizer LM, Schweizer M.

FEMS Yeast Res. 2006 Aug;6(5):716-25.

PMID:
16879423
[PubMed - indexed for MEDLINE]
20.

Ramifications of impaired PRPP synthesis in Saccharomyces cerevisiae.

Vavassori S, Wang K, Schweizer LM, Schweizer M.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1418-20. Review.

PMID:
16246134
[PubMed - indexed for MEDLINE]

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