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Results: 1 to 20 of 118

1.

Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.

Asgari E, Farrar CA, Lynch N, Ali YM, Roscher S, Stover C, Zhou W, Schwaeble WJ, Sacks SH.

FASEB J. 2014 May 27. pii: fj.13-246306. [Epub ahead of print]

PMID:
24868011
[PubMed - as supplied by publisher]
2.

Trypanosoma cruzi calreticulin inhibits the complement lectin pathway activation by direct interaction with L-Ficolin.

Sosoniuk E, Vallejos G, Kenawy H, Gaboriaud C, Thielens N, Fujita T, Schwaeble W, Ferreira A, Valck C.

Mol Immunol. 2014 Jul;60(1):80-5. doi: 10.1016/j.molimm.2014.03.014. Epub 2014 Apr 24.

PMID:
24769495
[PubMed - indexed for MEDLINE]
3.

Septicaemia models using Streptococcus pneumoniae and Listeria monocytogenes: understanding the role of complement properdin.

Dupont A, Mohamed F, Salehen N, Glenn S, Francescut L, Adib R, Byrne S, Brewin H, Elliott I, Richards L, Dimitrova P, Schwaeble W, Ivanovska N, Kadioglu A, Machado LR, Andrew PW, Stover C.

Med Microbiol Immunol. 2014 Apr 12. [Epub ahead of print]

PMID:
24728387
[PubMed - as supplied by publisher]
4.

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.

Ali YM, Hayat A, Saeed BM, Haleem KS, Alshamrani S, Kenawy HI, Ferreira VP, Saggu G, Buchberger A, Lachmann PJ, Sim RB, Goundis D, Andrew PW, Lynch NJ, Schwaeble WJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5301-6. doi: 10.1073/pnas.1401011111. Epub 2014 Mar 24.

PMID:
24706855
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae.

Ali YM, Kenawy HI, Muhammad A, Sim RB, Andrew PW, Schwaeble WJ.

PLoS One. 2013 Dec 12;8(12):e82583. doi: 10.1371/journal.pone.0082583. eCollection 2013.

PMID:
24349316
[PubMed - in process]
Free PMC Article
6.

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation.

Venkatraman Girija U, Gingras AR, Marshall JE, Panchal R, Sheikh MA, Gál P, Schwaeble WJ, Mitchell DA, Moody PC, Wallis R.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13916-20. doi: 10.1073/pnas.1311113110. Epub 2013 Aug 6.

PMID:
23922389
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of ficolin-A and lectin complement pathway in the innate defense against pathogenic Aspergillus species.

Bidula S, Kenawy H, Ali YM, Sexton D, Schwaeble WJ, Schelenz S.

Infect Immun. 2013 May;81(5):1730-40. doi: 10.1128/IAI.00032-13. Epub 2013 Mar 11.

PMID:
23478320
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Targeting complement at the time of transplantation.

Sacks S, Karegli J, Farrar CA, Asgari E, Schwaeble W, Zhou W, Smith RA.

Adv Exp Med Biol. 2013;735:247-55. Review.

PMID:
23402032
[PubMed - indexed for MEDLINE]
9.

Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency.

Ruseva MM, Vernon KA, Lesher AM, Schwaeble WJ, Ali YM, Botto M, Cook T, Song W, Stover CM, Pickering MC.

J Am Soc Nephrol. 2013 Jan;24(1):43-52. doi: 10.1681/ASN.2012060571. Epub 2012 Nov 26.

PMID:
23184055
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Which pathways trigger the role of complement in ischaemia/reperfusion injury?

Farrar CA, Asgari E, Schwaeble WJ, Sacks SH.

Front Immunol. 2012 Nov 19;3:341. doi: 10.3389/fimmu.2012.00341. eCollection 2012.

PMID:
23181062
[PubMed]
Free PMC Article
11.

Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection.

Endo Y, Takahashi M, Iwaki D, Ishida Y, Nakazawa N, Kodama T, Matsuzaka T, Kanno K, Liu Y, Tsuchiya K, Kawamura I, Ikawa M, Waguri S, Wada I, Matsushita M, Schwaeble WJ, Fujita T.

J Immunol. 2012 Dec 15;189(12):5860-6. doi: 10.4049/jimmunol.1200836. Epub 2012 Nov 12.

PMID:
23150716
[PubMed - indexed for MEDLINE]
Free Article
12.

The complement system in ischemia-reperfusion injuries.

Gorsuch WB, Chrysanthou E, Schwaeble WJ, Stahl GL.

Immunobiology. 2012 Nov;217(11):1026-33. doi: 10.1016/j.imbio.2012.07.024. Epub 2012 Aug 7. Review.

PMID:
22964228
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Abrogated RANKL expression in properdin-deficient mice is associated with better outcome from collagen-antibody-induced arthritis.

Dimitrova P, Ivanovska N, Belenska L, Milanova V, Schwaeble W, Stover C.

Arthritis Res Ther. 2012 Jul 25;14(4):R173. [Epub ahead of print]

PMID:
22830570
[PubMed - as supplied by publisher]
Free PMC Article
14.

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.

Ali YM, Lynch NJ, Haleem KS, Fujita T, Endo Y, Hansen S, Holmskov U, Takahashi K, Stahl GL, Dudler T, Girija UV, Wallis R, Kadioglu A, Stover CM, Andrew PW, Schwaeble WJ.

PLoS Pathog. 2012;8(7):e1002793. doi: 10.1371/journal.ppat.1002793. Epub 2012 Jul 5.

PMID:
22792067
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm.

Zhou HF, Yan H, Stover CM, Fernandez TM, Rodriguez de Cordoba S, Song WC, Wu X, Thompson RW, Schwaeble WJ, Atkinson JP, Hourcade DE, Pham CT.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):E415-22. doi: 10.1073/pnas.1119000109. Epub 2012 Jan 30.

PMID:
22308431
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections.

Kenawy HI, Ali YM, Rajakumar K, Lynch NJ, Kadioglu A, Stover CM, Schwaeble WJ.

Immunobiology. 2012 Feb;217(2):272-80. doi: 10.1016/j.imbio.2011.10.001. Epub 2011 Oct 13.

PMID:
22070931
[PubMed - indexed for MEDLINE]
17.

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.

Schwaeble WJ, Lynch NJ, Clark JE, Marber M, Samani NJ, Ali YM, Dudler T, Parent B, Lhotta K, Wallis R, Farrar CA, Sacks S, Lee H, Zhang M, Iwaki D, Takahashi M, Fujita T, Tedford CE, Stover CM.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7523-8. doi: 10.1073/pnas.1101748108. Epub 2011 Apr 18.

PMID:
21502512
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The lectin pathway of complement activation contributes to protection from West Nile virus infection.

Fuchs A, Pinto AK, Schwaeble WJ, Diamond MS.

Virology. 2011 Mar 30;412(1):101-9. doi: 10.1016/j.virol.2011.01.003. Epub 2011 Jan 26.

PMID:
21269656
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin.

Fuchs A, Lin TY, Beasley DW, Stover CM, Schwaeble WJ, Pierson TC, Diamond MS.

Cell Host Microbe. 2010 Aug 19;8(2):186-95. doi: 10.1016/j.chom.2010.07.007.

PMID:
20709295
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Use of recombinant calreticulin and cercarial transformation fluid (CTF) in the serodiagnosis of Schistosoma mansoni.

El Aswad Bel D, Doenhoff MJ, El Hadidi AS, Schwaeble WJ, Lynch NJ.

Immunobiology. 2011 Mar;216(3):379-85. doi: 10.1016/j.imbio.2010.06.014. Epub 2010 Jul 15.

PMID:
20691496
[PubMed - indexed for MEDLINE]

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