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Results: 1 to 20 of 40


Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains.

Shin DL, Pandey AK, Ziebarth JD, Mulligan MK, Williams RW, Geffers R, Hatesuer B, Schughart K, Wilk E.

G3 (Bethesda). 2014 Dec 17;5(2):235-9. doi: 10.1534/g3.114.015164.


The interferon-induced gene Ifi27l2a is active in lung macrophages and lymphocytes after influenza A infection but deletion of Ifi27l2a in mice does not increase susceptibility to infection.

Tantawy MA, Hatesuer B, Wilk E, Dengler L, Kasnitz N, Weiß S, Schughart K.

PLoS One. 2014 Sep 3;9(9):e106392. doi: 10.1371/journal.pone.0106392. eCollection 2014.


Cellular changes in blood indicate severe respiratory disease during influenza infections in mice.

Dengler L, Kühn N, Shin DL, Hatesuer B, Schughart K, Wilk E.

PLoS One. 2014 Jul 24;9(7):e103149. doi: 10.1371/journal.pone.0103149. eCollection 2014.


Systems genetics of liver fibrosis: identification of fibrogenic and expression quantitative trait loci in the BXD murine reference population.

Hall RA, Liebe R, Hochrath K, Kazakov A, Alberts R, Laufs U, Böhm M, Fischer HP, Williams RW, Schughart K, Weber SN, Lammert F.

PLoS One. 2014 Feb 28;9(2):e89279. doi: 10.1371/journal.pone.0089279. eCollection 2014.


Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Hatesuer B, Bertram S, Mehnert N, Bahgat MM, Nelson PS, Pöhlman S, Schughart K.

PLoS Pathog. 2013;9(12):e1003774. doi: 10.1371/journal.ppat.1003774. Epub 2013 Dec 5.


Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice.

Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F.

BMC Microbiol. 2013 Dec 17;13:293. doi: 10.1186/1471-2180-13-293.


The bioluminescent Listeria monocytogenes strain Xen32 is defective in flagella expression and highly attenuated in orally infected BALB/cJ mice.

Bergmann S, Rohde M, Schughart K, Lengeling A.

Gut Pathog. 2013 Jul 15;5(1):19. doi: 10.1186/1757-4749-5-19.


ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains.

Dogan A, Lasch P, Neuschl C, Millrose MK, Alberts R, Schughart K, Naumann D, Brockmann GA.

BMC Genomics. 2013 Jun 10;14:386. doi: 10.1186/1471-2164-14-386.


Controlling complexity: the clinical relevance of mouse complex genetics.

Schughart K, Libert C; SYSGENET consortium, Kas MJ.

Eur J Hum Genet. 2013 Nov;21(11):1191-6. doi: 10.1038/ejhg.2013.79. Epub 2013 May 1. Review.


Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.

Bergmann S, Beard PM, Pasche B, Lienenklaus S, Weiss S, Gahan CG, Schughart K, Lengeling A.

BMC Microbiol. 2013 Apr 23;13:90. doi: 10.1186/1471-2180-13-90.


PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.

He F, Chen H, Probst-Kepper M, Geffers R, Eifes S, Del Sol A, Schughart K, Zeng AP, Balling R.

Mol Syst Biol. 2012;8:624. doi: 10.1038/msb.2012.56.


Equivalence of self- and staff-collected nasal swabs for the detection of viral respiratory pathogens.

Akmatov MK, Gatzemeier A, Schughart K, Pessler F.

PLoS One. 2012;7(11):e48508. doi: 10.1371/journal.pone.0048508. Epub 2012 Nov 14.


Structural and functional concepts in current mouse phenotyping and archiving facilities.

Kollmus H, Post R, Brielmeier M, Fernández J, Fuchs H, McKerlie C, Montoliu L, Otaegui PJ, Rebelo M, Riedesel H, Ruberte J, Sedlacek R, de Angelis MH, Schughart K.

J Am Assoc Lab Anim Sci. 2012 Jul;51(4):418-35.


Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.

Dengler L, May M, Wilk E, Bahgat MM, Schughart K.

Virol J. 2012 Sep 19;9:212. doi: 10.1186/1743-422X-9-212.


Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.

Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K.

BMC Genomics. 2012 Aug 20;13:411. doi: 10.1186/1471-2164-13-411.


Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses.

Pommerenke C, Wilk E, Srivastava B, Schulze A, Novoselova N, Geffers R, Schughart K.

PLoS One. 2012;7(7):e41169. doi: 10.1371/journal.pone.0041169. Epub 2012 Jul 17.


Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.

Durrant C, Swertz MA, Alberts R, Arends D, Möller S, Mott R, Prins P, van der Velde KJ, Jansen RC, Schughart K.

Brief Bioinform. 2012 Mar;13(2):135-42. doi: 10.1093/bib/bbr026. Epub 2011 Jul 8. Review.


Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Alberts R, Chen H, Pommerenke C, Smit AB, Spijker S, Williams RW, Geffers R, Bruder D, Schughart K.

BMC Genomics. 2011 Dec 19;12:610. doi: 10.1186/1471-2164-12-610.


Dynamic gene network reconstruction from gene expression data in mice after influenza A (H1N1) infection.

Dimitrakopoulou K, Tsimpouris C, Papadopoulos G, Pommerenke C, Wilk E, Sgarbas KN, Schughart K, Bezerianos A.

J Clin Bioinforma. 2011 Oct 21;1:27. doi: 10.1186/2043-9113-1-27.


Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures.

Alberts R, Lu L, Williams RW, Schughart K.

Respir Res. 2011 May 2;12:61. doi: 10.1186/1465-9921-12-61. Erratum in: Respir Res. 2012;13(1):5.

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