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Results: 1 to 20 of 96


Protection from severe influenza infections in mice carrying the Mx1 influenza resistance gene strongly depends on genetic background.

Shin DL, Hatesuer B, Bergmann S, Nedelko T, Schughart K.

J Virol. 2015 Jul 22. pii: JVI.01305-15. [Epub ahead of print]


Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains.

Preusse M, Schughart K, Wilk E, Klawonn F, Pessler F.

BMC Res Notes. 2015 Jun 6;8:225. doi: 10.1186/s13104-015-1195-8.


Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes.

Janecek E, Wilk E, Schughart K, Geffers R, Strube C.

Int J Parasitol. 2015 Jun;45(7):495-503. doi: 10.1016/j.ijpara.2015.02.009. Epub 2015 Apr 3.


Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains.

Shin DL, Pandey AK, Ziebarth JD, Mulligan MK, Williams RW, Geffers R, Hatesuer B, Schughart K, Wilk E.

G3 (Bethesda). 2014 Dec 17;5(2):235-9. doi: 10.1534/g3.114.015164.


The interferon-induced gene Ifi27l2a is active in lung macrophages and lymphocytes after influenza A infection but deletion of Ifi27l2a in mice does not increase susceptibility to infection.

Tantawy MA, Hatesuer B, Wilk E, Dengler L, Kasnitz N, Weiß S, Schughart K.

PLoS One. 2014 Sep 3;9(9):e106392. doi: 10.1371/journal.pone.0106392. eCollection 2014.


Cellular changes in blood indicate severe respiratory disease during influenza infections in mice.

Dengler L, Kühn N, Shin DL, Hatesuer B, Schughart K, Wilk E.

PLoS One. 2014 Jul 24;9(7):e103149. doi: 10.1371/journal.pone.0103149. eCollection 2014.


Systems biology and systems genetics - novel innovative approaches to study host-pathogen interactions during influenza infection.

Kollmus H, Wilk E, Schughart K.

Curr Opin Virol. 2014 Jun;6:47-54. doi: 10.1016/j.coviro.2014.03.008. Epub 2014 Apr 23. Review.


Systems genetics of liver fibrosis: identification of fibrogenic and expression quantitative trait loci in the BXD murine reference population.

Hall RA, Liebe R, Hochrath K, Kazakov A, Alberts R, Laufs U, Böhm M, Fischer HP, Williams RW, Schughart K, Weber SN, Lammert F.

PLoS One. 2014 Feb 28;9(2):e89279. doi: 10.1371/journal.pone.0089279. eCollection 2014.


Influenza A immunomics and public health omics: the dynamic pathway interplay in host response to H1N1 infection.

Dimitrakopoulou K, Dimitrakopoulos GN, Wilk E, Tsimpouris C, Sgarbas KN, Schughart K, Bezerianos A.

OMICS. 2014 Mar;18(3):167-83. doi: 10.1089/omi.2013.0062. Epub 2014 Feb 10.


Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Hatesuer B, Bertram S, Mehnert N, Bahgat MM, Nelson PS, Pöhlmann S, Schughart K.

PLoS Pathog. 2013;9(12):e1003774. doi: 10.1371/journal.ppat.1003774. Epub 2013 Dec 5. Erratum in: PLoS Pathog. 2014 Sep;10(9):e1004435. Pöhlman, Stefan [corrected to Pöhlmann, Stefan].


Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice.

Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F.

BMC Microbiol. 2013 Dec 17;13:293. doi: 10.1186/1471-2180-13-293.


IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E.

J Immunol. 2013 Oct 1;191(7):3913-21. doi: 10.4049/jimmunol.1203305. Epub 2013 Sep 6.


The bioluminescent Listeria monocytogenes strain Xen32 is defective in flagella expression and highly attenuated in orally infected BALB/cJ mice.

Bergmann S, Rohde M, Schughart K, Lengeling A.

Gut Pathog. 2013 Jul 15;5(1):19. doi: 10.1186/1757-4749-5-19.


ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains.

Dogan A, Lasch P, Neuschl C, Millrose MK, Alberts R, Schughart K, Naumann D, Brockmann GA.

BMC Genomics. 2013 Jun 10;14:386. doi: 10.1186/1471-2164-14-386.


Meeting report of the European mouse complex genetics network SYSGENET.

Delprato A, Aransay AM, Kollmus H, Schughart K, Falcon-Perez JM.

Mamm Genome. 2013 Jun;24(5-6):190-7. doi: 10.1007/s00335-013-9458-y. Epub 2013 May 15.


Controlling complexity: the clinical relevance of mouse complex genetics.

Schughart K, Libert C; SYSGENET consortium, Kas MJ.

Eur J Hum Genet. 2013 Nov;21(11):1191-6. doi: 10.1038/ejhg.2013.79. Epub 2013 May 1. Review.


Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.

Bergmann S, Beard PM, Pasche B, Lienenklaus S, Weiss S, Gahan CG, Schughart K, Lengeling A.

BMC Microbiol. 2013 Apr 23;13:90. doi: 10.1186/1471-2180-13-90.


Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts.

Shepelkova G, Pommerenke C, Alberts R, Geffers R, Evstifeev V, Apt A, Schughart K, Wilk E.

Tuberculosis (Edinb). 2013 Mar;93(2):263-9. doi: 10.1016/ Epub 2012 Dec 29.


Human disease: Strength to strength for mouse models.

Schughart K, Libert C, Kas MJ.

Nature. 2012 Dec 6;492(7427):41. doi: 10.1038/492041c. No abstract available.


PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.

He F, Chen H, Probst-Kepper M, Geffers R, Eifes S, Del Sol A, Schughart K, Zeng AP, Balling R.

Mol Syst Biol. 2012;8:624. doi: 10.1038/msb.2012.56.

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