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Results: 1 to 20 of 1795

1.

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.

Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ.

Elife. 2015 May 22;4. doi: 10.7554/eLife.05920.

2.

Optimizing the inflammatory bowel disease unit to improve quality of care: expert recommendations.

Louis E, Dotan I, Ghosh S, Mlynarsky L, Reenaers C, Schreiber S.

J Crohns Colitis. 2015 May 18. pii: jjv085. [Epub ahead of print]

PMID:
25987349
3.

KRAS genomic status predicts sensitivity to decitabine in an extended assay in ovarian cancer cell lines.

Stewart ML, Tamayo P, Wilson AJ, Wang S, Chang YM, Kim JW, Khabele D, Shamji AF, Schreiber SL.

Cancer Res. 2015 May 12. pii: canres.2860.2014. [Epub ahead of print]

PMID:
25968887
4.

Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.

Dockendorff C, Faloon PW, Germain A, Yu M, Youngsaye W, Nag PP, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M.

Bioorg Med Chem Lett. 2015 Jun 15;25(12):2594-8. doi: 10.1016/j.bmcl.2015.03.074. Epub 2015 Apr 11.

5.

Polymorphisms in the mitochondrially encoded ATP synthase 8 gene are associated with susceptibility to bullous pemphigoid in the German population.

Hirose M, Schilf P, Benoit S, Eming R, Gläser R, Homey B, Kunz M, Nebel A, Peitsch WK, Pföhler C, Sárdy M, Schreiber S, Zillikens D, Schmidt E, Ibrahim SM; German AIBD Genetic Study Group.

Exp Dermatol. 2015 May 2. doi: 10.1111/exd.12732. [Epub ahead of print] No abstract available.

PMID:
25941154
6.

Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.

Dockendorff C, Faloon PW, Pu J, Yu M, Johnston S, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M.

Bioorg Med Chem Lett. 2015 May 15;25(10):2100-5. doi: 10.1016/j.bmcl.2015.03.073. Epub 2015 Apr 1.

7.

Externalization of neuronal somata as an evolutionary strategy for energy economization.

Hesse J, Schreiber S.

Curr Biol. 2015 Apr 20;25(8):R324-5. doi: 10.1016/j.cub.2015.02.024.

PMID:
25898099
8.

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells.

Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E, Resnick E, Goldacker S, Buchta M, Witte T, Padyukov L, Videm V, Folseraas T, Atschekzei F, Elder JT, Nair RP, Winkelmann J, Gieger C, Nöthen MM, Büning C, Brand S, Sullivan KE, Orange JS, Fevang B, Schreiber S, Lieb W, Aukrust P, Chapel H, Cunningham-Rundles C, Franke A, Karlsen TH, Grimbacher B, Hakonarson H, Hammarström L, Ellinghaus E.

Nat Commun. 2015 Apr 20;6:6804. doi: 10.1038/ncomms7804.

PMID:
25891430
9.

Delayed Transcranial Echo-Contrast Bolus Arrival in Unilateral Internal Carotid Artery Stenosis and Occlusion.

Gómez-Choco M, Schreiber SJ, Weih M, Doepp F, Valdueza JM.

Ultrasound Med Biol. 2015 Apr 15. pii: S0301-5629(15)00231-8. doi: 10.1016/j.ultrasmedbio.2015.03.018. [Epub ahead of print]

PMID:
25890887
10.

PLIP: fully automated protein-ligand interaction profiler.

Salentin S, Schreiber S, Haupt VJ, Adasme MF, Schroeder M.

Nucleic Acids Res. 2015 Apr 14. pii: gkv315. [Epub ahead of print]

11.

Discovery of a Small-Molecule Probe for V-ATPase Function.

Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ.

J Am Chem Soc. 2015 Apr 29;137(16):5563-8. doi: 10.1021/jacs.5b02150. Epub 2015 Apr 20.

12.

Genetically determined height and coronary artery disease.

Nelson CP, Hamby SE, Saleheen D, Hopewell JC, Zeng L, Assimes TL, Kanoni S, Willenborg C, Burgess S, Amouyel P, Anand S, Blankenberg S, Boehm BO, Clarke RJ, Collins R, Dedoussis G, Farrall M, Franks PW, Groop L, Hall AS, Hamsten A, Hengstenberg C, Hovingh GK, Ingelsson E, Kathiresan S, Kee F, König IR, Kooner J, Lehtimäki T, März W, McPherson R, Metspalu A, Nieminen MS, O'Donnell CJ, Palmer CN, Peters A, Perola M, Reilly MP, Ripatti S, Roberts R, Salomaa V, Shah SH, Schreiber S, Siegbahn A, Thorsteinsdottir U, Veronesi G, Wareham N, Willer CJ, Zalloua PA, Erdmann J, Deloukas P, Watkins H, Schunkert H, Danesh J, Thompson JR, Samani NJ; CARDIoGRAM+C4D Consortium.

N Engl J Med. 2015 Apr 23;372(17):1608-18. doi: 10.1056/NEJMoa1404881. Epub 2015 Apr 8.

13.

Discovering Small Molecules that Overcome Differentiation Arrest in Acute Myeloid Leukemia.

Sykes DB, Haynes MK, Waller A, Garcia M, Ursu O, Gouveia KE, Sklar L, Lewis TA, Dandapani S, Munoz B, Scadden DT, Palmer M, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 15 [updated 2015 Feb 11].

14.

Discovery and Evaluation of Fungicidal Anti-Cryptococcal Molecules.

Hartland CL, Pu J, Krysan D, Didone L, Moquist PN, Dandapani S, Munoz B, Palmer M, Schreiber S.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

15.

Discovery of small molecule probe that shows anti-tubercular activity via Mtb bioA (DAPA synthase) enzyme inhibition.

Casalena D, Nag PP, Park SW, Wilson D, Edwankar R, Johnston S, Le H, Schilling R, Bittker JA, Dandapani S, Munoz B, Dai R, Finzel BC, Schnappinger D, Aldrich C, Schreiber SL, Palmer M.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

16.

Identification of a chemically validated target in replicating and non-replicating Mycobacterium tuberculosis with the aid of a small molecule probe.

Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Fitzgerald M, Nietupski R, Gomez J, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa M, Rasmussen L, Johnston S, Bittker JA, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

17.
18.

Soluble receptor for advanced glycation end products as a potential biomarker to predict weight loss and improvement of insulin sensitivity by a very low calorie diet of obese human subjects.

Hagen I, Schulte DM, Müller N, Martinsen J, Türk K, Hedderich J, Schreiber S, Laudes M.

Cytokine. 2015 Jun;73(2):265-9. doi: 10.1016/j.cyto.2015.02.022. Epub 2015 Mar 21.

PMID:
25802195
19.

State-dependencies of learning across brain scales.

Ritter P, Born J, Brecht M, Dinse HR, Heinemann U, Pleger B, Schmitz D, Schreiber S, Villringer A, Kempter R.

Front Comput Neurosci. 2015 Feb 26;9:1. doi: 10.3389/fncom.2015.00001. eCollection 2015. Review.

20.

Everolimus maintenance in patients with mantle cell lymphoma not eligible for intensive therapy: results of a prematurely closed phase 2 study.

Schreiber S, Hoellein A, Decker T, Jilg S, Dreyling M, Peschel C, Keller U.

Leuk Lymphoma. 2015 Mar 31:1-3. [Epub ahead of print] No abstract available.

PMID:
25754578
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