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Results: 1 to 20 of 188

1.

Affinity polymers tailored for the protein A binding site of immunoglobulin G proteins.

Latza P, Gilles P, Schaller T, Schrader T.

Chemistry. 2014 Sep 1;20(36):11479-87. doi: 10.1002/chem.201402399. Epub 2014 Jul 24.

PMID:
25059560
[PubMed - in process]
2.

Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase.

Casadei CM, Gumiero A, Metcalfe CL, Murphy EJ, Basran J, Concilio MG, Teixeira SC, Schrader TE, Fielding AJ, Ostermann A, Blakeley MP, Raven EL, Moody PC.

Science. 2014 Jul 11;345(6193):193-7. doi: 10.1126/science.1254398. Epub 2014 Jul 10.

PMID:
25013070
[PubMed - indexed for MEDLINE]
3.

Safety and pharmacological characterization of the molecular tweezer CLR01 - a broad-spectrum inhibitor of amyloid proteins' toxicity.

Attar A, Chan WT, Klärner FG, Schrader T, Bitan G.

BMC Pharmacol Toxicol. 2014 Apr 16;15:23. doi: 10.1186/2050-6511-15-23.

PMID:
24735982
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate.

Yokoyama T, Ostermann A, Mizuguchi M, Niimura N, Schrader TE, Tanaka I.

Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):470-2. doi: 10.1107/S2053230X14004087. Epub 2014 Mar 25.

PMID:
24699741
[PubMed - in process]
5.

Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ.

J Biol Chem. 2014 Apr 11;289(15):10727-37. doi: 10.1074/jbc.M113.524520. Epub 2014 Feb 24.

PMID:
24567327
[PubMed - indexed for MEDLINE]
6.

Molecular tweezers targeting transthyretin amyloidosis.

Ferreira N, Pereira-Henriques A, Attar A, Klärner FG, Schrader T, Bitan G, Gales L, Saraiva MJ, Almeida MR.

Neurotherapeutics. 2014 Apr;11(2):450-61. doi: 10.1007/s13311-013-0256-8.

PMID:
24459092
[PubMed - in process]
Free PMC Article
7.

Isomerization- and temperature-jump-induced dynamics of a photoswitchable β-hairpin.

Deeg AA, Rampp MS, Popp A, Pilles BM, Schrader TE, Moroder L, Hauser K, Zinth W.

Chemistry. 2014 Jan 13;20(3):694-703. doi: 10.1002/chem.201303189. Epub 2013 Dec 20.

PMID:
24415361
[PubMed - indexed for MEDLINE]
8.

Neutron diffraction studies towards deciphering the protonation state of catalytic residues in the bacterial KDN9P phosphatase.

Bryan T, González JM, Bacik JP, DeNunzio NJ, Unkefer CJ, Schrader TE, Ostermann A, Dunaway-Mariano D, Allen KN, Fisher SZ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1015-9. doi: 10.1107/S1744309113021386. Epub 2013 Aug 19.

PMID:
23989152
[PubMed - indexed for MEDLINE]
9.

Molecular tweezers with varying anions: a comparative study.

Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo-Rodriguez K, Hanni M, Sánchez-García E, Ochsenfeld C, Klärner FG, Schrader T.

J Org Chem. 2013 Jul 5;78(13):6721-34. doi: 10.1021/jo4009673. Epub 2013 Jun 18.

PMID:
23750919
[PubMed - indexed for MEDLINE]
10.

Molecular tweezers modulate 14-3-3 protein-protein interactions.

Bier D, Rose R, Bravo-Rodriguez K, Bartel M, Ramirez-Anguita JM, Dutt S, Wilch C, Klärner FG, Sanchez-Garcia E, Schrader T, Ottmann C.

Nat Chem. 2013 Mar;5(3):234-9. doi: 10.1038/nchem.1570. Epub 2013 Feb 17.

PMID:
23422566
[PubMed - indexed for MEDLINE]
11.

Following the energy transfer in and out of a polyproline-peptide.

Schreier WJ, Aumüller T, Haiser K, Koller FO, Löweneck M, Musiol HJ, Schrader TE, Kiefhaber T, Moroder L, Zinth W.

Biopolymers. 2013 Apr;100(1):38-50. doi: 10.1002/bip.22171.

PMID:
23335166
[PubMed - in process]
12.

Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus.

Esser D, Kouril T, Talfournier F, Polkowska J, Schrader T, Bräsen C, Siebers B.

Extremophiles. 2013 Mar;17(2):205-16. doi: 10.1007/s00792-012-0507-3. Epub 2013 Jan 8.

PMID:
23296511
[PubMed - indexed for MEDLINE]
13.

Neutron and X-ray crystal structures of a perdeuterated enzyme inhibitor complex reveal the catalytic proton network of the Toho-1 β-lactamase for the acylation reaction.

Tomanicek SJ, Standaert RF, Weiss KL, Ostermann A, Schrader TE, Ng JD, Coates L.

J Biol Chem. 2013 Feb 15;288(7):4715-22. doi: 10.1074/jbc.M112.436238. Epub 2012 Dec 18.

PMID:
23255594
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Complementary asymmetric routes to (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate.

Schrader TO, Johnson BR, Lopez L, Kasem M, Gharbaoui T, Sengupta D, Buzard D, Basmadjian C, Jones RM.

Org Lett. 2012 Dec 21;14(24):6306-9. doi: 10.1021/ol303070k. Epub 2012 Dec 4.

PMID:
23210718
[PubMed - indexed for MEDLINE]
15.

Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers.

Attar A, Ripoli C, Riccardi E, Maiti P, Li Puma DD, Liu T, Hayes J, Jones MR, Lichti-Kaiser K, Yang F, Gale GD, Tseng CH, Tan M, Xie CW, Straudinger JL, Klärner FG, Schrader T, Frautschy SA, Grassi C, Bitan G.

Brain. 2012 Dec;135(Pt 12):3735-48. doi: 10.1093/brain/aws289. Epub 2012 Nov 26.

PMID:
23183235
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Terahertz radiation at 0.380 THz and 2.520 THz does not lead to DNA damage in skin cells in vitro.

Hintzsche H, Jastrow C, Heinen B, Baaske K, Kleine-Ostmann T, Schwerdtfeger M, Shakfa MK, Kärst U, Koch M, Schrader T, Stopper H.

Radiat Res. 2013 Jan;179(1):38-45. doi: 10.1667/RR3077.1. Epub 2012 Nov 26.

PMID:
23181591
[PubMed - indexed for MEDLINE]
17.

Terahertz electromagnetic fields (0.106 THz) do not induce manifest genomic damage in vitro.

Hintzsche H, Jastrow C, Kleine-Ostmann T, Kärst U, Schrader T, Stopper H.

PLoS One. 2012;7(9):e46397. doi: 10.1371/journal.pone.0046397. Epub 2012 Sep 27.

PMID:
23029508
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Artificial signal transduction with primary and secondary messengers.

Bernitzki K, Maue M, Schrader T.

Chemistry. 2012 Oct 15;18(42):13412-7. doi: 10.1002/chem.201200623. Epub 2012 Sep 7.

PMID:
22961842
[PubMed - indexed for MEDLINE]
19.

Standards and specifications in pathology: image management, report management and terminology.

Daniel C, Booker D, Beckwith B, Della Mea V, García-Rojo M, Havener L, Kennedy M, Klossa J, Laurinavicius A, Macary F, Punys V, Scharber W, Schrader T.

Stud Health Technol Inform. 2012;179:105-22.

PMID:
22925792
[PubMed - indexed for MEDLINE]
20.

State of the art in pathology business process analysis, modeling, design and optimization.

Schrader T, Blobel B, García-Rojo M, Daniel C, Słodkowska J.

Stud Health Technol Inform. 2012;179:88-102. Review.

PMID:
22925790
[PubMed - indexed for MEDLINE]

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