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Items: 1 to 20 of 207

1.

Intraoperative Monitoring of Epiphyseal Perfusion in Slipped Capital Femoral Epiphysis.

Schrader T, Jones CR, Kaufman AM, Herzog MM.

J Bone Joint Surg Am. 2016 Jun 15;98(12):1030-40. doi: 10.2106/JBJS.15.01002.

PMID:
27307364
2.

Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos.

Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM.

Environ Health Perspect. 2016 Jun 15. [Epub ahead of print]

3.

Reducing synuclein accumulation improves neuronal survival after spinal cord injury.

Fogerson SM, van Brummen AJ, Busch DJ, Allen SR, Roychaudhuri R, Banks SM, Klärner FG, Schrader T, Bitan G, Morgan JR.

Exp Neurol. 2016 Apr;278:105-15. doi: 10.1016/j.expneurol.2016.02.004. Epub 2016 Feb 13.

PMID:
26854933
4.

Protein Camouflage: Supramolecular Anion Recognition by Ubiquitin.

Mallon M, Dutt S, Schrader T, Crowley PB.

Chembiochem. 2016 Apr 15;17(8):774-83. doi: 10.1002/cbic.201500477. Epub 2016 Mar 15.

PMID:
26818656
5.

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.

Kathum OA, Schräder T, Anhlan D, Nordhoff C, Liedmann S, Pande A, Mellmann A, Ehrhardt C, Wixler V, Ludwig S.

Cell Microbiol. 2016 Jun;18(6):784-91. doi: 10.1111/cmi.12559. Epub 2016 Jan 27.

PMID:
26687707
6.

Exploring the Mechanism of β-Lactam Ring Protonation in the Class A β-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography.

Vandavasi VG, Weiss KL, Cooper JB, Erskine PT, Tomanicek SJ, Ostermann A, Schrader TE, Ginell SL, Coates L.

J Med Chem. 2016 Jan 14;59(1):474-9. doi: 10.1021/acs.jmedchem.5b01215. Epub 2015 Dec 2.

PMID:
26630115
7.

Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.

Wan Q, Parks JM, Hanson BL, Fisher SZ, Ostermann A, Schrader TE, Graham DE, Coates L, Langan P, Kovalevsky A.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12384-9. doi: 10.1073/pnas.1504986112. Epub 2015 Sep 21.

8.

Toxicity inhibitors protect lipid membranes from disruption by Aβ42.

Malishev R, Nandi S, Kolusheva S, Levi-Kalisman Y, Klärner FG, Schrader T, Bitan G, Jelinek R.

ACS Chem Neurosci. 2015 Nov 18;6(11):1860-9. doi: 10.1021/acschemneuro.5b00200. Epub 2015 Sep 9.

PMID:
26317327
9.

Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase.

Yokoyama T, Mizuguchi M, Ostermann A, Kusaka K, Niimura N, Schrader TE, Tanaka I.

J Med Chem. 2015 Sep 24;58(18):7549-56. doi: 10.1021/acs.jmedchem.5b01147. Epub 2015 Sep 4.

PMID:
26314394
10.

A molecular tweezer antagonizes seminal amyloids and HIV infection.

Lump E, Castellano LM, Meier C, Seeliger J, Erwin N, Sperlich B, Stürzel CM, Usmani S, Hammond RM, von Einem J, Gerold G, Kreppel F, Bravo-Rodriguez K, Pietschmann T, Holmes VM, Palesch D, Zirafi O, Weissman D, Sowislok A, Wettig B, Heid C, Kirchhoff F, Weil T, Klärner FG, Schrader T, Bitan G, Sanchez-Garcia E, Winter R, Shorter J, Münch J.

Elife. 2015 Aug 18;4. doi: 10.7554/eLife.05397.

11.

Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase.

Ohlin M, von Schantz L, Schrader TE, Ostermann A, Logan DT, Fisher SZ.

Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):1072-7. doi: 10.1107/S2053230X15011383. Epub 2015 Jul 29.

PMID:
26249702
12.

The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity.

Herzog G, Shmueli MD, Levy L, Engel L, Gazit E, Klärner FG, Schrader T, Bitan G, Segal D.

Biochemistry. 2015 Jun 23;54(24):3729-38. doi: 10.1021/bi501092p. Epub 2015 Jun 11.

PMID:
26030124
13.

Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.

Michalczyk R, Unkefer CJ, Bacik JP, Schrader TE, Ostermann A, Kovalevsky AY, McKenna R, Fisher SZ.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5673-8. doi: 10.1073/pnas.1502255112. Epub 2015 Apr 20.

14.

Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism.

Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G.

ACS Chem Biol. 2015 Jun 19;10(6):1555-69. doi: 10.1021/acschembio.5b00146. Epub 2015 Apr 16.

PMID:
25844890
15.

Amyloid β-protein assembly: The effect of molecular tweezers CLR01 and CLR03.

Zheng X, Liu D, Klärner FG, Schrader T, Bitan G, Bowers MT.

J Phys Chem B. 2015 Apr 9;119(14):4831-41. doi: 10.1021/acs.jpcb.5b00692. Epub 2015 Mar 16.

16.

Hybridization of an Aβ-specific antibody fragment with aminopyrazole-based β-sheet ligands displays striking enhancement of target affinity.

Hellmert M, Müller-Schiffmann A, Peters MS, Korth C, Schrader T.

Org Biomol Chem. 2015 Mar 14;13(10):2974-9. doi: 10.1039/c4ob02411g.

PMID:
25613910
17.

A reference model based interface terminology for generic observations in Anatomic Pathology Structured Reports.

Haroske G, Schrader T.

Diagn Pathol. 2014;9 Suppl 1:S4. doi: 10.1186/1746-1596-9-S1-S4. Epub 2014 Dec 19.

18.

Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor.

Buzard DJ, Schrader TO, Zhu X, Lehmann J, Johnson B, Kasem M, Kim SH, Kawasaki A, Lopez L, Moody J, Han S, Gao Y, Edwards J, Barden J, Thatte J, Gatlin J, Jones RM.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):659-63. doi: 10.1016/j.bmcl.2014.11.089. Epub 2014 Dec 9.

PMID:
25532755
19.

(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.

Buzard DJ, Lopez L, Moody J, Kawasaki A, Schrader TO, Kasem M, Johnson B, Zhu X, Thoresen L, Kim SH, Gharbaoui T, Sengupta D, Calvano L, Krishnan A, Gao Y, Semple G, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Chen W, Christopher RJ, Thatte J, Fu L, Solomon M, Whelan K, Al-Shamma H, Gatlin J, Gaidarov I, Anthony T, Le M, Unett DJ, Stirn S, Blackburn A, Behan DP, Jones RM.

ACS Med Chem Lett. 2014 Nov 25;5(12):1334-9. doi: 10.1021/ml500422m. eCollection 2014 Dec 11.

20.

Affinity polymers tailored for the protein A binding site of immunoglobulin G proteins.

Latza P, Gilles P, Schaller T, Schrader T.

Chemistry. 2014 Sep 1;20(36):11479-87. doi: 10.1002/chem.201402399. Epub 2014 Jul 24.

PMID:
25059560
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