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Results: 1 to 20 of 194

1.

A reference model based interface terminology for generic observations in Anatomic Pathology Structured Reports.

Haroske G, Schrader T.

Diagn Pathol. 2014 Dec;9(1):1067. doi: 10.1186/1746-1596-9-S1-S4.

2.

Amyloid β-Protein Assembly: The Effect of Molecular Tweezers CLR01 and CLR03.

Zheng X, Liu D, Klärner FG, Schrader T, Bitan G, Bowers MT.

J Phys Chem B. 2015 Mar 16. [Epub ahead of print]

PMID:
25751170
3.

Hybridization of an Aβ-specific antibody fragment with aminopyrazole-based β-sheet ligands displays striking enhancement of target affinity.

Hellmert M, Müller-Schiffmann A, Peters MS, Korth C, Schrader T.

Org Biomol Chem. 2015 Feb 24;13(10):2974-9. doi: 10.1039/c4ob02411g.

PMID:
25613910
4.

A reference model based interface terminology for generic observations in Anatomic Pathology Structured Reports.

Haroske G, Schrader T.

Diagn Pathol. 2014;9 Suppl 1:S4. doi: 10.1186/1746-1596-9-S1-S4. Epub 2014 Dec 19.

5.

Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor.

Buzard DJ, Schrader TO, Zhu X, Lehmann J, Johnson B, Kasem M, Kim SH, Kawasaki A, Lopez L, Moody J, Han S, Gao Y, Edwards J, Barden J, Thatte J, Gatlin J, Jones RM.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):659-63. doi: 10.1016/j.bmcl.2014.11.089. Epub 2014 Dec 9.

PMID:
25532755
6.

(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.

Buzard DJ, Lopez L, Moody J, Kawasaki A, Schrader TO, Kasem M, Johnson B, Zhu X, Thoresen L, Kim SH, Gharbaoui T, Sengupta D, Calvano L, Krishnan A, Gao Y, Semple G, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Chen W, Christopher RJ, Thatte J, Fu L, Solomon M, Whelan K, Al-Shamma H, Gatlin J, Gaidarov I, Anthony T, Le M, Unett DJ, Stirn S, Blackburn A, Behan DP, Jones RM.

ACS Med Chem Lett. 2014 Nov 25;5(12):1334-9. doi: 10.1021/ml500422m. eCollection 2014 Dec 11.

PMID:
25516794
7.

Affinity polymers tailored for the protein A binding site of immunoglobulin G proteins.

Latza P, Gilles P, Schaller T, Schrader T.

Chemistry. 2014 Sep 1;20(36):11479-87. doi: 10.1002/chem.201402399. Epub 2014 Jul 24.

PMID:
25059560
8.

Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase.

Casadei CM, Gumiero A, Metcalfe CL, Murphy EJ, Basran J, Concilio MG, Teixeira SC, Schrader TE, Fielding AJ, Ostermann A, Blakeley MP, Raven EL, Moody PC.

Science. 2014 Jul 11;345(6193):193-7. doi: 10.1126/science.1254398. Epub 2014 Jul 10.

PMID:
25013070
9.

Safety and pharmacological characterization of the molecular tweezer CLR01 - a broad-spectrum inhibitor of amyloid proteins' toxicity.

Attar A, Chan WT, Klärner FG, Schrader T, Bitan G.

BMC Pharmacol Toxicol. 2014 Apr 16;15:23. doi: 10.1186/2050-6511-15-23.

10.

Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate.

Yokoyama T, Ostermann A, Mizuguchi M, Niimura N, Schrader TE, Tanaka I.

Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):470-2. doi: 10.1107/S2053230X14004087. Epub 2014 Mar 25.

PMID:
24699741
11.

Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ.

J Biol Chem. 2014 Apr 11;289(15):10727-37. doi: 10.1074/jbc.M113.524520. Epub 2014 Feb 24.

PMID:
24567327
12.

Molecular tweezers targeting transthyretin amyloidosis.

Ferreira N, Pereira-Henriques A, Attar A, Klärner FG, Schrader T, Bitan G, Gales L, Saraiva MJ, Almeida MR.

Neurotherapeutics. 2014 Apr;11(2):450-61. doi: 10.1007/s13311-013-0256-8.

13.

Isomerization- and temperature-jump-induced dynamics of a photoswitchable β-hairpin.

Deeg AA, Rampp MS, Popp A, Pilles BM, Schrader TE, Moroder L, Hauser K, Zinth W.

Chemistry. 2014 Jan 13;20(3):694-703. doi: 10.1002/chem.201303189. Epub 2013 Dec 20.

PMID:
24415361
14.

Neutron diffraction studies towards deciphering the protonation state of catalytic residues in the bacterial KDN9P phosphatase.

Bryan T, González JM, Bacik JP, DeNunzio NJ, Unkefer CJ, Schrader TE, Ostermann A, Dunaway-Mariano D, Allen KN, Fisher SZ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1015-9. doi: 10.1107/S1744309113021386. Epub 2013 Aug 19.

PMID:
23989152
15.

Molecular tweezers with varying anions: a comparative study.

Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo-Rodriguez K, Hanni M, Sánchez-García E, Ochsenfeld C, Klärner FG, Schrader T.

J Org Chem. 2013 Jul 5;78(13):6721-34. doi: 10.1021/jo4009673. Epub 2013 Jun 18.

PMID:
23750919
16.

Molecular tweezers modulate 14-3-3 protein-protein interactions.

Bier D, Rose R, Bravo-Rodriguez K, Bartel M, Ramirez-Anguita JM, Dutt S, Wilch C, Klärner FG, Sanchez-Garcia E, Schrader T, Ottmann C.

Nat Chem. 2013 Mar;5(3):234-9. doi: 10.1038/nchem.1570. Epub 2013 Feb 17.

PMID:
23422566
17.

Following the energy transfer in and out of a polyproline-peptide.

Schreier WJ, Aumüller T, Haiser K, Koller FO, Löweneck M, Musiol HJ, Schrader TE, Kiefhaber T, Moroder L, Zinth W.

Biopolymers. 2013 Apr;100(1):38-50. doi: 10.1002/bip.22171.

PMID:
23335166
18.

Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus.

Esser D, Kouril T, Talfournier F, Polkowska J, Schrader T, Bräsen C, Siebers B.

Extremophiles. 2013 Mar;17(2):205-16. doi: 10.1007/s00792-012-0507-3. Epub 2013 Jan 8.

PMID:
23296511
19.

Neutron and X-ray crystal structures of a perdeuterated enzyme inhibitor complex reveal the catalytic proton network of the Toho-1 β-lactamase for the acylation reaction.

Tomanicek SJ, Standaert RF, Weiss KL, Ostermann A, Schrader TE, Ng JD, Coates L.

J Biol Chem. 2013 Feb 15;288(7):4715-22. doi: 10.1074/jbc.M112.436238. Epub 2012 Dec 18.

20.

Complementary asymmetric routes to (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate.

Schrader TO, Johnson BR, Lopez L, Kasem M, Gharbaoui T, Sengupta D, Buzard D, Basmadjian C, Jones RM.

Org Lett. 2012 Dec 21;14(24):6306-9. doi: 10.1021/ol303070k. Epub 2012 Dec 4.

PMID:
23210718
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