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Items: 1 to 20 of 21

1.

Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease.

Dand N, Schulz R, Weale ME, Southgate L, Oakey RJ, Simpson MA, Schlitt T.

Hum Mutat. 2015 Dec;36(12):1135-44. doi: 10.1002/humu.22906. Epub 2015 Oct 7.

PMID:
26394720
2.

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.

Prescott NJ, Lehne B, Stone K, Lee JC, Taylor K, Knight J, Papouli E, Mirza MM, Simpson MA, Spain SL, Lu G, Fraternali F, Bumpstead SJ, Gray E, Amar A, Bye H, Green P, Chung-Faye G, Hayee B, Pollok R, Satsangi J, Parkes M, Barrett JC, Mansfield JC, Sanderson J, Lewis CM, Weale ME, Schlitt T, Mathew CG; UK IBD Genetics Consortium.

PLoS Genet. 2015 Feb 11;11(2):e1004955. doi: 10.1371/journal.pgen.1004955. eCollection 2015 Feb. Erratum in: PLoS Genet. 2015 Apr;11(4):e1005172.

3.

Predicting the functional consequences of non-synonymous DNA sequence variants--evaluation of bioinformatics tools and development of a consensus strategy.

Frousios K, Iliopoulos CS, Schlitt T, Simpson MA.

Genomics. 2013 Oct;102(4):223-8. doi: 10.1016/j.ygeno.2013.06.005. Epub 2013 Jul 3.

4.

Approaches to modeling gene regulatory networks: a gentle introduction.

Schlitt T.

Methods Mol Biol. 2013;1021:13-35. doi: 10.1007/978-1-62703-450-0_2.

PMID:
23715978
5.

BioGranat-IG: a network analysis tool to suggest mechanisms of genetic heterogeneity from exome-sequencing data.

Dand N, Sprengel F, Ahlers V, Schlitt T.

Bioinformatics. 2013 Mar 15;29(6):733-41. doi: 10.1093/bioinformatics/btt045. Epub 2013 Jan 29.

6.

HSM - a hybrid system based approach for modelling intracellular networks.

Brazma A, Cerans K, Ruklisa D, Schlitt T, Viksna J.

Gene. 2013 Apr 10;518(1):70-7. doi: 10.1016/j.gene.2012.11.084. Epub 2012 Dec 21.

PMID:
23266641
7.

Breaking free from the chains of pathway annotation: de novo pathway discovery for the analysis of disease processes.

Lehne B, Schlitt T.

Pharmacogenomics. 2012 Dec;13(16):1967-78. doi: 10.2217/pgs.12.170.

PMID:
23215889
8.

From SNPs to genes: disease association at the gene level.

Lehne B, Lewis CM, Schlitt T.

PLoS One. 2011;6(6):e20133. doi: 10.1371/journal.pone.0020133. Epub 2011 Jun 30.

9.

Exome localization of complex disease association signals.

Lehne B, Lewis CM, Schlitt T.

BMC Genomics. 2011 Feb 1;12:92. doi: 10.1186/1471-2164-12-92.

10.
11.

Learning about gene regulatory networks from gene deletion experiments.

Schlitt T, Brazma A.

Comp Funct Genomics. 2002;3(6):499-503. doi: 10.1002/cfg.220.

12.

Domain II hairpin structure in ITS1 sequences as an aid in differentiating recently evolved animal and plant pathogenic fungi.

Bridge PD, Schlitt T, Cannon PF, Buddie AG, Baker M, Borman AM.

Mycopathologia. 2008 Jul;166(1):1-16. doi: 10.1007/s11046-008-9094-3. Epub 2008 Mar 14.

PMID:
18340548
13.

Current approaches to gene regulatory network modelling.

Schlitt T, Brazma A.

BMC Bioinformatics. 2007 Sep 27;8 Suppl 6:S9.

14.

Modelling in molecular biology: describing transcription regulatory networks at different scales.

Schlitt T, Brazma A.

Philos Trans R Soc Lond B Biol Sci. 2006 Mar 29;361(1467):483-94. Review.

15.
16.

Modelling gene networks at different organisational levels.

Schlitt T, Brazma A.

FEBS Lett. 2005 Mar 21;579(8):1859-66. Review.

17.

From microarray data to results. Workshop on genomic approaches to microarray data analysis.

Schlitt T, Kemmeren P.

EMBO Rep. 2004 May;5(5):459-63. Epub 2004 Apr 23. No abstract available.

18.

From gene networks to gene function.

Schlitt T, Palin K, Rung J, Dietmann S, Lappe M, Ukkonen E, Brazma A.

Genome Res. 2003 Dec;13(12):2568-76.

19.

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain.

Tenbaum SP, Juenemann S, Schlitt T, Bernal J, Renkawitz R, Muñoz A, Baniahmad A.

Dev Biol. 2003 Feb 1;254(1):149-60.

20.

Building and analysing genome-wide gene disruption networks.

Rung J, Schlitt T, Brazma A, Freivalds K, Vilo J.

Bioinformatics. 2002;18 Suppl 2:S202-10.

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