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Items: 1 to 20 of 125


Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation.

Bai G, Smolka MB, Schimenti JC.

PLoS Genet. 2016 Jan 14;12(1):e1005787. doi: 10.1371/journal.pgen.1005787. eCollection 2016 Jan.


MCM9 deficiency delays primordial germ cell proliferation independent of the ATM pathway.

Luo Y, Schimenti JC.

Genesis. 2015 Nov;53(11):678-84. doi: 10.1002/dvg.22901. Epub 2015 Oct 14.


The genetics of human infertility by functional interrogation of SNPs in mice.

Singh P, Schimenti JC.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10431-6. doi: 10.1073/pnas.1506974112. Epub 2015 Aug 3.


Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes.

Lee CY, Horn HF, Stewart CL, Burke B, Bolcun-Filas E, Schimenti JC, Dresser ME, Pezza RJ.

Cell Rep. 2015 Apr 28;11(4):551-63. doi: 10.1016/j.celrep.2015.03.045. Epub 2015 Apr 16.


Effects of Deletion of ERα in Osteoblast-Lineage Cells on Bone Mass and Adaptation to Mechanical Loading Differ in Female and Male Mice.

Melville KM, Kelly NH, Surita G, Buchalter DB, Schimenti JC, Main RP, Ross FP, van der Meulen MC.

J Bone Miner Res. 2015 Aug;30(8):1468-80. doi: 10.1002/jbmr.2488. Epub 2015 May 22.


Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability.

Pattabiraman S, Baumann C, Guisado D, Eppig JJ, Schimenti JC, De La Fuente R.

J Cell Biol. 2015 Jan 5;208(1):53-69. doi: 10.1083/jcb.201404109. Epub 2014 Dec 29.


A mouse geneticist's practical guide to CRISPR applications.

Singh P, Schimenti JC, Bolcun-Filas E.

Genetics. 2015 Jan;199(1):1-15. doi: 10.1534/genetics.114.169771. Epub 2014 Sep 29. Review.


A method for isolating high quality RNA from mouse cortical and cancellous bone.

Kelly NH, Schimenti JC, Patrick Ross F, van der Meulen MC.

Bone. 2014 Nov;68:1-5. doi: 10.1016/j.bone.2014.07.022. Epub 2014 Jul 26.


Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling.

Luo Y, Hartford SA, Zeng R, Southard TL, Shima N, Schimenti JC.

PLoS Genet. 2014 Jul 10;10(7):e1004471. doi: 10.1371/journal.pgen.1004471. eCollection 2014 Jul. Erratum in: PLoS Genet. 2014 Sep;10(9):e1004730.


Applying "gold standards" to in-vitro-derived germ cells.

Handel MA, Eppig JJ, Schimenti JC.

Cell. 2014 Jun 5;157(6):1257-61. doi: 10.1016/j.cell.2014.05.019. Erratum in: Cell. 2014 Sep 25;159(1):216.


Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro.

Schnabel LV, Abratte CM, Schimenti JC, Felippe MJ, Cassano JM, Southard TL, Cross JA, Fortier LA.

Regen Med. 2014;9(5):621-35. doi: 10.2217/rme.14.29. Epub 2014 Apr 28.


miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment.

Cheng CY, Hwang CI, Corney DC, Flesken-Nikitin A, Jiang L, Oner GM, Munroe RJ, Schimenti JC, Hermeking H, Nikitin AY.

Cell Rep. 2014 Mar 27;6(6):1000-7. doi: 10.1016/j.celrep.2014.02.023. Epub 2014 Mar 13. Erratum in: Cell Rep. 2015 Sep 29;12(12):2181.


STAG3 is a strong candidate gene for male infertility.

Llano E, Gomez-H L, García-Tuñón I, Sánchez-Martín M, Caburet S, Barbero JL, Schimenti JC, Veitia RA, Pendas AM.

Hum Mol Genet. 2014 Jul 1;23(13):3421-31. doi: 10.1093/hmg/ddu051. Epub 2014 Mar 7.


Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway.

Bolcun-Filas E, Rinaldi VD, White ME, Schimenti JC.

Science. 2014 Jan 31;343(6170):533-6. doi: 10.1126/science.1247671.


IQ motif-containing G (Iqcg) is required for mouse spermiogenesis.

Harris TP, Schimenti KJ, Munroe RJ, Schimenti JC.

G3 (Bethesda). 2014 Feb 19;4(2):367-72. doi: 10.1534/g3.113.009563.


Female mice lacking estrogen receptor-alpha in osteoblasts have compromised bone mass and strength.

Melville KM, Kelly NH, Khan SA, Schimenti JC, Ross FP, Main RP, van der Meulen MC.

J Bone Miner Res. 2014 Feb;29(2):370-9. doi: 10.1002/jbmr.2082.


Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.

Wallace MD, Southard TL, Schimenti KJ, Schimenti JC.

Oncogene. 2014 Jul 10;33(28):3688-95. doi: 10.1038/onc.2013.339. Epub 2013 Aug 26.


AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice.

Schimenti KJ, Feuer SK, Griffin LB, Graham NR, Bovet CA, Hartford S, Pendola J, Lessard C, Schimenti JC, Ward JO.

Genetics. 2013 Jun;194(2):447-57. doi: 10.1534/genetics.113.150789. Epub 2013 Apr 22.


An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes.

Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW, Xu J, Moore MJ, Schimenti JC, Weng Z, Zamore PD.

Mol Cell. 2013 Apr 11;50(1):67-81. doi: 10.1016/j.molcel.2013.02.016. Epub 2013 Mar 21.


The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.

Park J, Long DT, Lee KY, Abbas T, Shibata E, Negishi M, Luo Y, Schimenti JC, Gambus A, Walter JC, Dutta A.

Mol Cell Biol. 2013 Apr;33(8):1632-44. doi: 10.1128/MCB.01503-12. Epub 2013 Feb 11.

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