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Inclusion of targeted therapies in the standard of care for metastatic colorectal cancer patients in a German cancer center: the more the better?!

Moehler M, Thomaidis T, Zeifri C, Barhoom T, Marquardt J, Ploch P, Schattenberg J, Maderer A, Schimanski CC, Weinmann A, Woerns MA, Kranich AL, Warnecke JM, Galle PR.

J Cancer Res Clin Oncol. 2015 Mar;141(3):515-22. doi: 10.1007/s00432-014-1829-6. Epub 2014 Sep 19.


Murine genetic deficiency of neuronal nitric oxide synthase (nNOS(-/-) ) and interstitial cells of Cajal (W/W(v) ): Implications for achalasia?

Müller M, Colcuc S, Drescher DG, Eckardt AJ, von Pein H, Taube C, Schumacher J, Gockel HR, Schimanski CC, Lang H, Gockel I.

J Gastroenterol Hepatol. 2014 Oct;29(10):1800-7. doi: 10.1111/jgh.12600.


Rectal cancer: dynamic contrast-enhanced MRI correlates with lymph node status and epidermal growth factor receptor expression.

Lollert A, Junginger T, Schimanski CC, Biesterfeld S, Gockel I, Düber C, Oberholzer K.

J Magn Reson Imaging. 2014 Jun;39(6):1436-42. doi: 10.1002/jmri.24301. Epub 2013 Oct 11.


Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective.

Wehler TC, Graf C, Möhler M, Herzog J, Berger MR, Gockel I, Lang H, Theobald M, Galle PR, Schimanski CC.

J Cancer Res Clin Oncol. 2013 Oct;139(10):1667-72. doi: 10.1007/s00432-013-1483-4. Epub 2013 Aug 7. Erratum in: J Cancer Res Clin Oncol. 2013 Nov;139(11):1961-2.


Erythropoietin treatment in chemotherapy-induced anemia in previously untreated advanced esophagogastric cancer patients.

Thomaidis T, Weinmann A, Sprinzl M, Kanzler S, Raedle J, Ebert M, Schimanski CC, Galle PR, Hoehler T, Moehler M; Upper-GI-Group of AIO (Arbeitsgemeinschaft Internistische Onkologie), Germany.

Int J Clin Oncol. 2014 Apr;19(2):288-96. doi: 10.1007/s10147-013-0544-7. Epub 2013 Mar 27.


Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction.

Moehler M, Gockel I, Roessler HP, Arnold D, Trarbach T, Thomaidis T, Klautke G, Rödel C, Brenner B, Lang H, Galle PR, Schimanski CC, Schmidberger H.

BMC Cancer. 2013 Feb 11;13:75. doi: 10.1186/1471-2407-13-75.


Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy.

Wehler TC, Hamdi S, Maderer A, Graf C, Gockel I, Schmidtmann I, Hainz M, Berger MR, Theobald M, Galle PR, Moehler M, Schimanski CC.

Int J Colorectal Dis. 2013 Mar;28(3):385-98. doi: 10.1007/s00384-012-1551-2. Epub 2012 Sep 15.


Preservation of HUGL-1 expression as a favourable prognostic factor in pancreatic carcinoma.

Biesterfeld S, Kauhausen A, Kost C, Gockel I, Schimanski CC, Galle PR.

Anticancer Res. 2012 Aug;32(8):3153-9.


Model of wound healing for esophagogastric anastomoses in rats.

Drescher DG, Vogt J, Gabriel M, Baumgart J, Schimanski CC, Lang H, Gockel I.

Eur Surg Res. 2012;48(4):194-9. doi: 10.1159/000338625. Epub 2012 Jun 7.


Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.

Mueller A, Bachmann E, Linnig M, Khillimberger K, Schimanski CC, Galle PR, Moehler M.

Cancer Chemother Pharmacol. 2012 Jun;69(6):1601-15. doi: 10.1007/s00280-012-1869-z. Epub 2012 Apr 29.


LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases: a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial.

Schimanski CC, Möhler M, Schön M, van Cutsem E, Greil R, Bechstein WO, Hegewisch-Becker S, von Wichert G, Vöhringer M, Heike M, Heinemann V, Peeters M, Kanzler S, Kasper S, Overkamp F, Schröder J, Seehofer D, Kullmann F, Linz B, Schmidtmann I, Smith-Machnow V, Gockel I, Lang H, Galle PR.

BMC Cancer. 2012 Apr 11;12:144. doi: 10.1186/1471-2407-12-144.


[With the scalpel against the immune system: HIV infection complicated by an unclear colitis].

Ploch P, Schimanski CC, Goetz M, Orth C, Lang H, Galle PR, Schuchmann M, Kittner JM.

Z Gastroenterol. 2012 Apr;50(4):382-5. doi: 10.1055/s-0031-1273454. Epub 2012 Apr 1. German.


Survival after chemotherapy and/or radiotherapy versus self-expanding metal stent insertion in the setting of inoperable esophageal cancer: a case-control study.

Sgourakis G, Gockel I, Karaliotas C, Moehler M, Schimanski CC, Schmidberger H, Junginger T.

BMC Cancer. 2012 Feb 15;12:70. doi: 10.1186/1471-2407-12-70.


Autocrine CSF-1 and CSF-1 receptor coexpression promotes renal cell carcinoma growth.

Menke J, Kriegsmann J, Schimanski CC, Schwartz MM, Schwarting A, Kelley VR.

Cancer Res. 2012 Jan 1;72(1):187-200. doi: 10.1158/0008-5472.CAN-11-1232. Epub 2011 Nov 3.


Etiopathological aspects of achalasia: lessons learned with Hirschsprung's disease.

Gockel HR, Gockel I, Schimanski CC, Schier F, Schumacher J, Nöthen MM, Lang H, Müller M, Eckardt AJ, Eckardt VF.

Dis Esophagus. 2012 Aug;25(6):566-72. doi: 10.1111/j.1442-2050.2011.01277.x. Epub 2011 Nov 2. Review.


SDF1β expression in renal cell carcinoma correlates with grading and infiltration by CD8+ T-cells.

Wehler TC, Graf C, Altherr K, Zimmermann T, Brenner W, Thüroff JW, Biesterfeld S, Gockel I, Theobald M, Galle PR, Schimanski CC.

Anticancer Res. 2011 Sep;31(9):2797-803.


Risk of lymph node metastasis in submucosal esophageal cancer: a review of surgically resected patients.

Gockel I, Sgourakis G, Lyros O, Polotzek U, Schimanski CC, Lang H, Hoppo T, Jobe BA.

Expert Rev Gastroenterol Hepatol. 2011 Jun;5(3):371-84. doi: 10.1586/egh.11.33. Review.


SNP rs1801157 significantly correlates with distant metastasis in CXCL12 expressing esophagogastric cancer.

Schimanski CC, Jordan M, Schlaegel F, Schmidtmann I, Lang H, Galle PR, Moehler M, Gockel I.

Int J Oncol. 2011 Aug;39(2):515-20. doi: 10.3892/ijo.2011.1044. Epub 2011 May 16.


Cetuximab-induced skin exanthema: Improvement by a reactive skin therapy.

Schimanski CC, Moehler M, Zimmermann T, Wörns MA, Steinbach A, Baum M, Galle PR.

Mol Med Rep. 2010 Sep-Oct;3(5):789-93. doi: 10.3892/mmr.2010.336. Epub 2010 Jul 20.

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