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Items: 1 to 20 of 92

1.

Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.

Boller S, Ramamoorthy S, Akbas D, Nechanitzky R, Burger L, Murr R, Schübeler D, Grosschedl R.

Immunity. 2016 Mar 15;44(3):527-41. doi: 10.1016/j.immuni.2016.02.021.

PMID:
26982363
2.

Competition between DNA methylation and transcription factors determines binding of NRF1.

Domcke S, Bardet AF, Adrian Ginno P, Hartl D, Burger L, Schübeler D.

Nature. 2015 Dec 24;528(7583):575-9. doi: 10.1038/nature16462. Epub 2015 Dec 16.

PMID:
26675734
3.

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation.

Zemke M, Draganova K, Klug A, Schöler A, Zurkirchen L, Gay MH, Cheng P, Koseki H, Valenta T, Schübeler D, Basler K, Sommer L.

BMC Biol. 2015 Nov 30;13:103. doi: 10.1186/s12915-015-0210-9.

4.

Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function.

Avrahami D, Li C, Zhang J, Schug J, Avrahami R, Rao S, Stadler MB, Burger L, Schübeler D, Glaser B, Kaestner KH.

Cell Metab. 2015 Oct 6;22(4):619-32. doi: 10.1016/j.cmet.2015.07.025. Epub 2015 Aug 27.

PMID:
26321660
5.

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers.

Stein C, Bardet AF, Roma G, Bergling S, Clay I, Ruchti A, Agarinis C, Schmelzle T, Bouwmeester T, Schübeler D, Bauer A.

PLoS Genet. 2015 Aug 21;11(8):e1005465. doi: 10.1371/journal.pgen.1005465. eCollection 2015 Aug.

6.

ESCI award lecture: regulation, function and biomarker potential of DNA methylation.

Schübeler D.

Eur J Clin Invest. 2015 Mar;45(3):288-93. doi: 10.1111/eci.12403. Epub 2015 Feb 14. Review.

PMID:
25608229
7.

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.

Baubec T, Colombo DF, Wirbelauer C, Schmidt J, Burger L, Krebs AR, Akalin A, Schübeler D.

Nature. 2015 Apr 9;520(7546):243-7. doi: 10.1038/nature14176. Epub 2015 Jan 21.

PMID:
25607372
8.

Function and information content of DNA methylation.

Schübeler D.

Nature. 2015 Jan 15;517(7534):321-6. doi: 10.1038/nature14192. Review.

PMID:
25592537
9.

Genomation: a toolkit to summarize, annotate and visualize genomic intervals.

Akalin A, Franke V, Vlahoviček K, Mason CE, Schübeler D.

Bioinformatics. 2015 Apr 1;31(7):1127-9. doi: 10.1093/bioinformatics/btu775. Epub 2014 Nov 21.

10.

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

Gilsbach R, Preissl S, Grüning BA, Schnick T, Burger L, Benes V, Würch A, Bönisch U, Günther S, Backofen R, Fleischmann BK, Schübeler D, Hein L.

Nat Commun. 2014 Oct 22;5:5288. doi: 10.1038/ncomms6288.

11.

High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions.

Krebs AR, Dessus-Babus S, Burger L, Schübeler D.

Elife. 2014 Sep 26;3:e04094. doi: 10.7554/eLife.04094.

12.

Short sequences can efficiently recruit histone H3 lysine 27 trimethylation in the absence of enhancer activity and DNA methylation.

Jermann P, Hoerner L, Burger L, Schübeler D.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3415-21. doi: 10.1073/pnas.1400672111. Epub 2014 Aug 4.

13.

DNA methylation is required for the control of stem cell differentiation in the small intestine.

Sheaffer KL, Kim R, Aoki R, Elliott EN, Schug J, Burger L, Schübeler D, Kaestner KH.

Genes Dev. 2014 Mar 15;28(6):652-64. doi: 10.1101/gad.230318.113.

14.

Genomic patterns and context specific interpretation of DNA methylation.

Baubec T, Schübeler D.

Curr Opin Genet Dev. 2014 Apr;25:85-92. doi: 10.1016/j.gde.2013.11.015. Epub 2014 Mar 7. Review.

PMID:
24614011
15.

DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes.

Gaidatzis D, Burger L, Murr R, Lerch A, Dessus-Babus S, Schübeler D, Stadler MB.

PLoS Genet. 2014 Feb 13;10(2):e1004143. doi: 10.1371/journal.pgen.1004143. eCollection 2014 Feb.

16.

Ezh2 is required for neural crest-derived cartilage and bone formation.

Schwarz D, Varum S, Zemke M, Schöler A, Baggiolini A, Draganova K, Koseki H, Schübeler D, Sommer L.

Development. 2014 Feb;141(4):867-77. doi: 10.1242/dev.094342.

17.

Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.

Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schübeler D.

PLoS Genet. 2013;9(12):e1003994. doi: 10.1371/journal.pgen.1003994. Epub 2013 Dec 19.

18.

Gene regulation and priming by topoisomerase IIα in embryonic stem cells.

Thakurela S, Garding A, Jung J, Schübeler D, Burger L, Tiwari VK.

Nat Commun. 2013;4:2478. doi: 10.1038/ncomms3478.

PMID:
24072229
19.

Twisting chromatin in stem cells.

Ginno P, Schübeler D.

EMBO J. 2013 Aug 28;32(17):2304-6. doi: 10.1038/emboj.2013.179. Epub 2013 Aug 6. No abstract available.

20.

Identification of active regulatory regions from DNA methylation data.

Burger L, Gaidatzis D, Schübeler D, Stadler MB.

Nucleic Acids Res. 2013 Sep;41(16):e155. doi: 10.1093/nar/gkt599. Epub 2013 Jul 4.

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