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Results: 1 to 20 of 72

1.

Epigenetics in the treatment of systemic lupus erythematosus: Potential clinical application.

Guo Y, Sawalha AH, Lu Q.

Clin Immunol. 2014 Sep 16;155(1):79-90. doi: 10.1016/j.clim.2014.09.002. [Epub ahead of print] Review.

PMID:
25218424
[PubMed - as supplied by publisher]
2.

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype.

Zhao M, Liu S, Luo S, Wu H, Tang M, Cheng W, Zhang Q, Zhang P, Yu X, Xia Y, Yi N, Gao F, Wang L, Yung S, Chan TM, Sawalha AH, Richardson B, Gershwin ME, Li N, Lu Q.

J Autoimmun. 2014 Aug 1. pii: S0896-8411(14)00115-2. doi: 10.1016/j.jaut.2014.07.002. [Epub ahead of print]

PMID:
25091625
[PubMed - as supplied by publisher]
3.

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Jeffries MA, Donica M, Baker L, Stevenson M, Annan AC, Humphrey MB, James JA, Sawalha AH.

Arthritis Rheumatol. 2014 Jun 30. doi: 10.1002/art.38762. [Epub ahead of print]

PMID:
24980887
[PubMed - as supplied by publisher]
4.

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.

Altorok N, Tsou PS, Coit P, Khanna D, Sawalha AH.

Ann Rheum Dis. 2014 May 8. pii: annrheumdis-2014-205303. doi: 10.1136/annrheumdis-2014-205303. [Epub ahead of print]

PMID:
24812288
[PubMed - as supplied by publisher]
5.

Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells from patients with Behçet's disease.

Hughes T, Ture-Ozdemir F, Alibaz-Oner F, Coit P, Direskeneli H, Sawalha AH.

Arthritis Rheumatol. 2014 Jun;66(6):1648-58. doi: 10.1002/art.38409.

PMID:
24574333
[PubMed - indexed for MEDLINE]
6.

Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.

Altorok N, Coit P, Hughes T, Koelsch KA, Stone DU, Rasmussen A, Radfar L, Scofield RH, Sivils KL, Farris AD, Sawalha AH.

Arthritis Rheumatol. 2014 Mar;66(3):731-9. doi: 10.1002/art.38264.

PMID:
24574234
[PubMed - indexed for MEDLINE]
7.

Protein kinase Cδ mutations may contribute to lupus through effects on T cells: comment on the article by Belot et al.

Richardson B, Strickland FM, Sawalha AH, Gorelik G.

Arthritis Rheumatol. 2014 Jan;66(1):228-9. doi: 10.1002/art.38235. No abstract available.

PMID:
24449588
[PubMed - indexed for MEDLINE]
8.

TIR-domain-containing adaptor protein gene TIRAP S180L polymorphism is not increased in Behçet's disease patients in two ethnic cohorts.

Turunc G, Coskun D, Alibaz-Oner F, Coit P, Duzgun N, Alpsoy E, Yentur SP, Salvarani C, Casali B, Kötter I, Ergun T, Direskeneli H, Sawalha AH, Saruhan-Direskeneli G.

Clin Exp Rheumatol. 2013 May-Jun;31(3 Suppl 77):54-6. Epub 2013 Sep 9.

PMID:
24064014
[PubMed - indexed for MEDLINE]
9.

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell LA, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, James JA, Kamen DL, Kaufman KM, Kelly JA, Martin J, Merrill JT, Moser KL, Niewold TB, Park SY, Pons-Estel BA, Sawalha AH, Scofield RH, Shen N, Stevens AM, Sun C, Gilkeson GS, Edberg JC, Kimberly RP, Nath SK, Tsao BP, Vyse TJ.

PLoS Genet. 2013;9(7):e1003554. doi: 10.1371/journal.pgen.1003554. Epub 2013 Jul 18.

PMID:
23874208
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Overexpression of methyl-CpG-binding protein 2 and autoimmunity: evidence from MECP2 duplication syndrome, lupus, MECP2 transgenic and Mecp2 deficient mice.

Sawalha AH.

Lupus. 2013 Aug;22(9):870-2. doi: 10.1177/0961203313497119. Epub 2013 Jul 16. No abstract available.

PMID:
23861028
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Epigenetics in the pathogenesis of systemic lupus erythematosus.

Altorok N, Sawalha AH.

Curr Opin Rheumatol. 2013 Sep;25(5):569-76. doi: 10.1097/BOR.0b013e328364206f. Review.

PMID:
23846340
[PubMed - indexed for MEDLINE]
12.

Identification of multiple genetic susceptibility loci in Takayasu arteritis.

Saruhan-Direskeneli G, Hughes T, Aksu K, Keser G, Coit P, Aydin SZ, Alibaz-Oner F, Kamalı S, Inanc M, Carette S, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Maksimowicz-McKinnon K, Monach PA, Ozer HT, Seyahi E, Fresko I, Cefle A, Seo P, Warrington KJ, Ozturk MA, Ytterberg SR, Cobankara V, Onat AM, Guthridge JM, James JA, Tunc E, Duzgun N, Bıcakcıgil M, Yentür SP, Merkel PA, Direskeneli H, Sawalha AH.

Am J Hum Genet. 2013 Aug 8;93(2):298-305. doi: 10.1016/j.ajhg.2013.05.026. Epub 2013 Jul 3.

PMID:
23830517
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.

Coit P, Jeffries M, Altorok N, Dozmorov MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ, Sawalha AH.

J Autoimmun. 2013 Jun;43:78-84. doi: 10.1016/j.jaut.2013.04.003. Epub 2013 Apr 24.

PMID:
23623029
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

GFP affects human T cell activation and cytokine production following in vitro stimulation.

Koelsch KA, Wang Y, Maier-Moore JS, Sawalha AH, Wren JD.

PLoS One. 2013;8(4):e50068. doi: 10.1371/journal.pone.0050068. Epub 2013 Apr 5.

PMID:
23577054
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.

Strickland FM, Hewagama A, Wu A, Sawalha AH, Delaney C, Hoeltzel MF, Yung R, Johnson K, Mickelson B, Richardson BC.

Arthritis Rheum. 2013 Jul;65(7):1872-81. doi: 10.1002/art.37967.

PMID:
23576011
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse.

Koelsch KA, Webb R, Jeffries M, Dozmorov MG, Frank MB, Guthridge JM, James JA, Wren JD, Sawalha AH.

J Autoimmun. 2013 Mar;41:168-74. doi: 10.1016/j.jaut.2012.12.012. Epub 2013 Feb 18.

PMID:
23428850
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification of multiple independent susceptibility loci in the HLA region in Behçet's disease.

Hughes T, Coit P, Adler A, Yilmaz V, Aksu K, Düzgün N, Keser G, Cefle A, Yazici A, Ergen A, Alpsoy E, Salvarani C, Casali B, Kötter I, Gutierrez-Achury J, Wijmenga C, Direskeneli H, Saruhan-Direskeneli G, Sawalha AH.

Nat Genet. 2013 Mar;45(3):319-24. doi: 10.1038/ng.2551. Epub 2013 Feb 10.

PMID:
23396137
[PubMed - indexed for MEDLINE]
18.

Impaired DNA methylation and its mechanisms in CD4(+)T cells of systemic lupus erythematosus.

Zhang Y, Zhao M, Sawalha AH, Richardson B, Lu Q.

J Autoimmun. 2013 Mar;41:92-9. doi: 10.1016/j.jaut.2013.01.005. Epub 2013 Jan 20. Review.

PMID:
23340289
[PubMed - indexed for MEDLINE]
19.

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress.

Tran L, Chaloner A, Sawalha AH, Greenwood Van-Meerveld B.

Psychoneuroendocrinology. 2013 Jun;38(6):898-906. doi: 10.1016/j.psyneuen.2012.09.016. Epub 2012 Oct 22.

PMID:
23084728
[PubMed - indexed for MEDLINE]
20.

Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus…).

Richardson B, Sawalha AH, Ray D, Yung R.

Methods Mol Biol. 2012;900:169-80. doi: 10.1007/978-1-60761-720-4_8.

PMID:
22933069
[PubMed - indexed for MEDLINE]

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