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Results: 1 to 20 of 79

1.

Activation of the JAK/STAT pathway in Behcet's disease.

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H.

Genes Immun. 2015 Mar;16(2):176. doi: 10.1038/gene.2014.80. No abstract available.

PMID:
25739881
2.

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.

Coit P, Yalavarthi S, Ognenovski M, Zhao W, Hasni S, Wren JD, Kaplan MJ, Sawalha AH.

J Autoimmun. 2015 Apr;58:59-66. doi: 10.1016/j.jaut.2015.01.004. Epub 2015 Jan 28.

PMID:
25638528
3.

Genome-wide association study identifies susceptibility loci in IL6, RPS9/LILRB3, and an intergenic locus on chromosome 21q22 in Takayasu's arteritis.

Renauer P, Saruhan-Direskeneli G, Coit P, Adler A, Aksu K, Keser G, Alibaz-Oner F, Aydin SZ, Kamali S, Inanc M, Carette S, Cuthbertson D, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, Maksimowicz-McKinnon K, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Duzgun N, Monach PA, Ozer HT, Erken E, Ozturk MA, Yazici A, Cefle A, Onat AM, Kisacik B, Pagnoux C, Kasifoglu T, Seyahi E, Fresko I, Seo P, Sreih A, Warrington KJ, Ytterberg SR, Cobankara V, Cunninghame-Graham DS, Vyse TJ, Pamuk ON, Tunc E, Dalkilic E, Bicakcigil M, Yentur SP, Wren JD, Merkel PA, Direskeneli H, Sawalha AH.

Arthritis Rheumatol. 2015 Jan 20. doi: 10.1002/art.39035. [Epub ahead of print]

PMID:
25604533
4.

Hydroxychloroquine-induced hyperpigmentation of the skin.

Sawalha AH.

J Rheumatol. 2015 Jan;42(1):135-6. doi: 10.3899/jrheum.140995. No abstract available.

PMID:
25554808
5.

Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?

Jeffries MA, Sawalha AH.

Expert Rev Clin Immunol. 2015 Jan;11(1):45-58. doi: 10.1586/1744666X.2015.994507.

PMID:
25534978
6.
7.

Activation of the JAK/STAT pathway in Behcet's disease.

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H.

Genes Immun. 2015 Mar;16(2):170-5. doi: 10.1038/gene.2014.64. Epub 2014 Nov 20.

PMID:
25410656
8.

Epigenetics in the treatment of systemic lupus erythematosus: potential clinical application.

Guo Y, Sawalha AH, Lu Q.

Clin Immunol. 2014 Nov;155(1):79-90. doi: 10.1016/j.clim.2014.09.002. Epub 2014 Sep 16. Review.

PMID:
25218424
9.

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype.

Zhao M, Liu S, Luo S, Wu H, Tang M, Cheng W, Zhang Q, Zhang P, Yu X, Xia Y, Yi N, Gao F, Wang L, Yung S, Chan TM, Sawalha AH, Richardson B, Gershwin ME, Li N, Lu Q.

J Autoimmun. 2014 Nov;54:127-36. doi: 10.1016/j.jaut.2014.07.002. Epub 2014 Aug 3.

PMID:
25091625
10.

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Jeffries MA, Donica M, Baker LW, Stevenson ME, Annan AC, Humphrey MB, James JA, Sawalha AH.

Arthritis Rheumatol. 2014 Oct;66(10):2804-15. doi: 10.1002/art.38762.

PMID:
24980887
11.

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.

Altorok N, Tsou PS, Coit P, Khanna D, Sawalha AH.

Ann Rheum Dis. 2014 May 8. pii: annrheumdis-2014-205303. doi: 10.1136/annrheumdis-2014-205303. [Epub ahead of print]

PMID:
24812288
12.

Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells from patients with Behçet's disease.

Hughes T, Ture-Ozdemir F, Alibaz-Oner F, Coit P, Direskeneli H, Sawalha AH.

Arthritis Rheumatol. 2014 Jun;66(6):1648-58. doi: 10.1002/art.38409.

PMID:
24574333
13.

Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.

Altorok N, Coit P, Hughes T, Koelsch KA, Stone DU, Rasmussen A, Radfar L, Scofield RH, Sivils KL, Farris AD, Sawalha AH.

Arthritis Rheumatol. 2014 Mar;66(3):731-9. doi: 10.1002/art.38264.

14.

Protein kinase Cδ mutations may contribute to lupus through effects on T cells: comment on the article by Belot et al.

Richardson B, Strickland FM, Sawalha AH, Gorelik G.

Arthritis Rheumatol. 2014 Jan;66(1):228-9. doi: 10.1002/art.38235. No abstract available.

PMID:
24449588
15.

TIR-domain-containing adaptor protein gene TIRAP S180L polymorphism is not increased in Behçet's disease patients in two ethnic cohorts.

Turunc G, Coskun D, Alibaz-Oner F, Coit P, Duzgun N, Alpsoy E, Yentur SP, Salvarani C, Casali B, Kötter I, Ergun T, Direskeneli H, Sawalha AH, Saruhan-Direskeneli G.

Clin Exp Rheumatol. 2013 May-Jun;31(3 Suppl 77):54-6. Epub 2013 Sep 9.

PMID:
24064014
16.

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell LA, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, James JA, Kamen DL, Kaufman KM, Kelly JA, Martin J, Merrill JT, Moser KL, Niewold TB, Park SY, Pons-Estel BA, Sawalha AH, Scofield RH, Shen N, Stevens AM, Sun C, Gilkeson GS, Edberg JC, Kimberly RP, Nath SK, Tsao BP, Vyse TJ.

PLoS Genet. 2013;9(7):e1003554. doi: 10.1371/journal.pgen.1003554. Epub 2013 Jul 18.

17.

Overexpression of methyl-CpG-binding protein 2 and autoimmunity: evidence from MECP2 duplication syndrome, lupus, MECP2 transgenic and Mecp2 deficient mice.

Sawalha AH.

Lupus. 2013 Aug;22(9):870-2. doi: 10.1177/0961203313497119. Epub 2013 Jul 16. No abstract available.

18.

Epigenetics in the pathogenesis of systemic lupus erythematosus.

Altorok N, Sawalha AH.

Curr Opin Rheumatol. 2013 Sep;25(5):569-76. doi: 10.1097/BOR.0b013e328364206f. Review.

PMID:
23846340
19.

Identification of multiple genetic susceptibility loci in Takayasu arteritis.

Saruhan-Direskeneli G, Hughes T, Aksu K, Keser G, Coit P, Aydin SZ, Alibaz-Oner F, Kamalı S, Inanc M, Carette S, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Maksimowicz-McKinnon K, Monach PA, Ozer HT, Seyahi E, Fresko I, Cefle A, Seo P, Warrington KJ, Ozturk MA, Ytterberg SR, Cobankara V, Onat AM, Guthridge JM, James JA, Tunc E, Duzgun N, Bıcakcıgil M, Yentür SP, Merkel PA, Direskeneli H, Sawalha AH.

Am J Hum Genet. 2013 Aug 8;93(2):298-305. doi: 10.1016/j.ajhg.2013.05.026. Epub 2013 Jul 3.

20.

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.

Coit P, Jeffries M, Altorok N, Dozmorov MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ, Sawalha AH.

J Autoimmun. 2013 Jun;43:78-84. doi: 10.1016/j.jaut.2013.04.003. Epub 2013 Apr 24.

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