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Items: 1 to 20 of 103

1.

Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma.

Triozzi PL, Achberger S, Aldrich W, Crabb JW, Saunthararajah Y, Singh AD.

Clin Epigenetics. 2016 Jul 22;8:80. doi: 10.1186/s13148-016-0243-0. eCollection 2016.

2.

GSK-3 Inhibition Sensitizes Acute Myeloid Leukemia Cells to 1,25D-Mediated Differentiation.

Gupta K, Stefan T, Ignatz-Hoover J, Moreton S, Parizher G, Saunthararajah Y, Wald DN.

Cancer Res. 2016 May 1;76(9):2743-53. doi: 10.1158/0008-5472.CAN-15-2290. Epub 2016 Mar 10.

PMID:
26964622
3.

Identification of a Small Molecule That Overcomes HdmX-Mediated Suppression of p53.

Karan G, Wang H, Chakrabarti A, Karan S, Liu Z, Xia Z, Gundluru M, Moreton S, Saunthararajah Y, Jackson MW, Agarwal MK, Wald DN.

Mol Cancer Ther. 2016 Apr;15(4):574-82. doi: 10.1158/1535-7163.MCT-15-0467. Epub 2016 Feb 16.

PMID:
26883273
4.

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).

Rivers A, Vaitkus K, Ibanez V, Ruiz MA, Jagadeeswaran R, Saunthararajah Y, Cui S, Engel JD, DeSimone J, Lavelle D.

Haematologica. 2016 Jun;101(6):688-97. doi: 10.3324/haematol.2015.140749. Epub 2016 Feb 8.

5.

Correction: Methylation Profiles Reveal Distinct Subgroup of Hepatocellular Carcinoma Patients with Poor Prognosis.

Mah WC, Thurnherr T, Chow PK, Chung AY, Ooi LL, Toh HC, Teh BT, Saunthararajah Y, Lee CG.

PLoS One. 2016 Jan 11;11(1):e0146690. doi: 10.1371/journal.pone.0146690. eCollection 2016. No abstract available.

6.

Prospective Clinical Study of Precision Oncology in Solid Tumors.

Sohal DP, Rini BI, Khorana AA, Dreicer R, Abraham J, Procop GW, Saunthararajah Y, Pennell NA, Stevenson JP, Pelley R, Estfan B, Shepard D, Funchain P, Elson P, Adelstein DJ, Bolwell BJ.

J Natl Cancer Inst. 2015 Nov 9;108(3). pii: djv332. doi: 10.1093/jnci/djv332.

PMID:
26553780
7.

Cx25 contributes to leukemia cell communication and chemosensitivity.

Sinyuk M, Alvarado AG, Nesmiyanov P, Shaw J, Mulkearns-Hubert EE, Eurich JT, Hale JS, Bogdanova A, Hitomi M, Maciejewski J, Huang AY, Saunthararajah Y, Lathia JD.

Oncotarget. 2015 Oct 13;6(31):31508-21. doi: 10.18632/oncotarget.5226.

8.

iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors.

Crabb JW, Hu B, Crabb JS, Triozzi P, Saunthararajah Y, Tubbs R, Singh AD.

PLoS One. 2015 Aug 25;10(8):e0135543. doi: 10.1371/journal.pone.0135543. eCollection 2015.

9.

The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.

Cui S, Lim KC, Shi L, Lee M, Jearawiriyapaisarn N, Myers G, Campbell A, Harro D, Iwase S, Trievel RC, Rivers A, DeSimone J, Lavelle D, Saunthararajah Y, Engel JD.

Blood. 2015 Jul 16;126(3):386-96. doi: 10.1182/blood-2015-02-626259. Epub 2015 Jun 1.

10.

Targets of opportunity for precision medicine.

Saunthararajah Y.

Blood. 2015 May 14;125(20):3041-2. doi: 10.1182/blood-2015-04-638270. No abstract available.

11.

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

Polprasert C, Schulze I, Sekeres MA, Makishima H, Przychodzen B, Hosono N, Singh J, Padgett RA, Gu X, Phillips JG, Clemente M, Parker Y, Lindner D, Dienes B, Jankowsky E, Saunthararajah Y, Du Y, Oakley K, Nguyen N, Mukherjee S, Pabst C, Godley LA, Churpek JE, Pollyea DA, Krug U, Berdel WE, Klein HU, Dugas M, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Yoshida K, Ogawa S, Müller-Tidow C, Maciejewski JP.

Cancer Cell. 2015 May 11;27(5):658-70. doi: 10.1016/j.ccell.2015.03.017. Epub 2015 Apr 23.

12.

Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.

Saunthararajah Y, Sekeres M, Advani A, Mahfouz R, Durkin L, Radivoyevitch T, Englehaupt R, Juersivich J, Cooper K, Husseinzadeh H, Przychodzen B, Rump M, Hobson S, Earl M, Sobecks R, Dean R, Reu F, Tiu R, Hamilton B, Copelan E, Lichtin A, Hsi E, Kalaycio M, Maciejewski J.

J Clin Invest. 2015 Mar 2;125(3):1043-55. doi: 10.1172/JCI78789. Epub 2015 Jan 26.

13.

Impact of vancomycin-resistant enterococcal bacteremia on outcome during acute myeloid leukemia induction therapy.

Ornstein MC, Mukherjee S, Keng M, Elson P, Tiu RV, Saunthararajah Y, Maggiotto A, Schaub M, Banks D, Advani A, Kalaycio M, Maciejewski JP, Sekeres MA.

Leuk Lymphoma. 2015;56(9):2536-42. doi: 10.3109/10428194.2014.1003557. Epub 2015 Feb 20.

PMID:
25563427
14.

Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts.

Visconte V, Tabarroki A, Zhang L, Parker Y, Hasrouni E, Mahfouz R, Isono K, Koseki H, Sekeres MA, Saunthararajah Y, Barnard J, Lindner D, Rogers HJ, Tiu RV.

J Hematol Oncol. 2014 Dec 7;7:89. doi: 10.1186/s13045-014-0089-x.

15.

Genomic microarray analysis on formalin-fixed paraffin-embedded material for uveal melanoma prognostication.

Minca EC, Tubbs RR, Portier BP, Wang Z, Lanigan C, Aronow ME, Triozzi PL, Singh A, Cook JR, Saunthararajah Y, Plesec TP, Schoenfield L, Cawich V, Sulpizio S, Schultz RA.

Cancer Genet. 2014 Jul-Aug;207(7-8):306-15. doi: 10.1016/j.cancergen.2014.08.005. Epub 2014 Aug 29.

PMID:
25442074
16.

Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis.

Mah WC, Thurnherr T, Chow PK, Chung AY, Ooi LL, Toh HC, Teh BT, Saunthararajah Y, Lee CG.

PLoS One. 2014 Aug 5;9(8):e104158. doi: 10.1371/journal.pone.0104158. eCollection 2014. Erratum in: PLoS One. 2016;11(1):e0146690.

17.

Decitabine suspends human CD34+ cell differentiation and proliferation during lentiviral transduction.

Uchida N, Hsieh MM, Platner C, Saunthararajah Y, Tisdale JF.

PLoS One. 2014 Aug 4;9(8):e104022. doi: 10.1371/journal.pone.0104022. eCollection 2014.

18.

Ligand exchange on gold nanoparticles for drug delivery and enhanced therapeutic index evaluated in acute myeloid leukemia models.

Egusa S, Ebrahem Q, Mahfouz RZ, Saunthararajah Y.

Exp Biol Med (Maywood). 2014 May 30;239(7):853-861. [Epub ahead of print]

PMID:
24879424
19.

Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron.

Visconte V, Avishai N, Mahfouz R, Tabarroki A, Cowen J, Sharghi-Moshtaghin R, Hitomi M, Rogers HJ, Hasrouni E, Phillips J, Sekeres MA, Heuer AH, Saunthararajah Y, Barnard J, Tiu RV.

Leukemia. 2015 Jan;29(1):188-95. doi: 10.1038/leu.2014.170. Epub 2014 May 23.

PMID:
24854990
20.

Clinicopathologic and molecular characterization of myeloid neoplasms harboring isochromosome 17(q10).

Visconte V, Tabarroki A, Zhang L, Hasrouni E, Gerace C, Frum R, Ai J, Advani AS, Duong HK, Kalaycio M, Saunthararajah Y, Sekeres MA, His ED, Shetty S, Rogers HJ, Tiu RV.

Am J Hematol. 2014 Aug;89(8):862. doi: 10.1002/ajh.23755. Epub 2014 May 16. No abstract available.

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