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Items: 1 to 20 of 126

1.

The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function.

Pfeffer TJ, Sasse F, Schmidt CF, Lakämper S, Kirschning A, Scholz T.

Eur J Med Chem. 2016 Apr 13;112:164-70. doi: 10.1016/j.ejmech.2016.02.022. Epub 2016 Feb 8.

PMID:
26896705
2.

Target identification by image analysis.

Fetz V, Prochnow H, Brönstrup M, Sasse F.

Nat Prod Rep. 2016 May 4;33(5):655-67. doi: 10.1039/c5np00113g. Review.

PMID:
26777141
3.

Synthesis of the AB ring system of clifednamide utilizing Claisen rearrangement and Diels-Alder reaction as key steps.

Loke I, Bentzinger G, Holz J, Raja A, Bhasin A, Sasse F, Köhn A, Schobert R, Laschat S.

Org Biomol Chem. 2016 Jan 21;14(3):884-94. doi: 10.1039/c5ob01491c. Epub 2015 Nov 24.

PMID:
26599642
4.

Paleo-soraphens: chemical total syntheses and biological studies.

Lu HH, Hinkelmann B, Tautz T, Li J, Sasse F, Franke R, Kalesse M.

Org Biomol Chem. 2015 Aug 7;13(29):8029-36. doi: 10.1039/c5ob01249j. Epub 2015 Jun 29.

PMID:
26119264
5.

The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide.

Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB 3rd, Lee D, Taylor RE, Sasse F, Kalesse M.

Angew Chem Int Ed Engl. 2015 Jun 1;54(23):6935-9. doi: 10.1002/anie.201501526. Epub 2015 Apr 27.

PMID:
25914374
6.

Design, synthesis, and biological evaluation of simplified side chain hybrids of the potent actin binding polyketides rhizopodin and bistramide.

Herkommer D, Dreisigacker S, Sergeev G, Sasse F, Gohlke H, Menche D.

ChemMedChem. 2015 Mar;10(3):470-89. doi: 10.1002/cmdc.201402508. Epub 2015 Jan 29.

PMID:
25641798
7.

New, non-quinone fluorogeldanamycin derivatives strongly inhibit Hsp90.

Hermane J, Bułyszko I, Eichner S, Sasse F, Collisi W, Poso A, Schax E, Walter JG, Scheper T, Kock K, Herrmann C, Aliuos P, Reuter G, Zeilinger C, Kirschning A.

Chembiochem. 2015 Jan 19;16(2):302-11. doi: 10.1002/cbic.201402375. Epub 2015 Jan 8.

PMID:
25572106
8.

Preparation of thermocleavable conjugates based on ansamitocin and superparamagnetic nanostructured particles by a chemobiosynthetic approach.

Mancuso L, Knobloch T, Buchholz J, Hartwig J, Möller L, Seidel K, Collisi W, Sasse F, Kirschning A.

Chemistry. 2014 Dec 22;20(52):17541-51. doi: 10.1002/chem.201404502. Epub 2014 Oct 24.

PMID:
25346489
9.

Antiviral drug discovery: broad-spectrum drugs from nature.

Martinez JP, Sasse F, Brönstrup M, Diez J, Meyerhans A.

Nat Prod Rep. 2015 Jan;32(1):29-48. doi: 10.1039/c4np00085d. Review.

PMID:
25315648
10.

Host range of the potential biopesticide Pea Albumin 1b (PA1b) is limited to insects.

Rahioui I, Eyraud V, Karaki L, Sasse F, Carre-Pierrat M, Qin A, Zheng MH, Toepfer S, Sivignon C, Royer C, Da Silva P, Gressent F.

Toxicon. 2014 Oct;89:67-76. doi: 10.1016/j.toxicon.2014.07.004. Epub 2014 Jul 23.

PMID:
25064271
11.

Sulfur, selenium and tellurium pseudopeptides: synthesis and biological evaluation.

Shaaban S, Sasse F, Burkholz T, Jacob C.

Bioorg Med Chem. 2014 Jul 15;22(14):3610-9. doi: 10.1016/j.bmc.2014.05.019. Epub 2014 May 21.

PMID:
24890655
12.

SAR studies on hydropentalene derivatives--Important core units of biologically active tetramic acid macrolactams and ptychanolides.

Lutz V, Mannchen F, Krebs M, Park N, Krüger C, Raja A, Sasse F, Baro A, Laschat S.

Bioorg Med Chem. 2014 Jul 1;22(13):3252-61. doi: 10.1016/j.bmc.2014.04.063. Epub 2014 May 9.

PMID:
24856181
13.

Preparative mass-spectrometry profiling of bioactive metabolites in Saudi-Arabian propolis fractionated by high-speed countercurrent chromatography and off-line atmospheric pressure chemical ionization mass-spectrometry injection.

Jerz G, Elnakady YA, Braun A, Jäckel K, Sasse F, Al Ghamdi AA, Omar MO, Winterhalter P.

J Chromatogr A. 2014 Jun 20;1347:17-29. doi: 10.1016/j.chroma.2014.04.068. Epub 2014 Apr 28.

PMID:
24831423
14.

Gold(I) biscarbene complexes derived from vascular-disrupting combretastatin A-4 address different targets and show antimetastatic potential.

Muenzner JK, Biersack B, Kalie H, Andronache IC, Kaps L, Schuppan D, Sasse F, Schobert R.

ChemMedChem. 2014 Jun;9(6):1195-204. doi: 10.1002/cmdc.201400049. Epub 2014 Mar 19.

PMID:
24648184
15.

Preparation of new alkyne-modified ansamitocins by mutasynthesis.

Harmrolfs K, Mancuso L, Drung B, Sasse F, Kirschning A.

Beilstein J Org Chem. 2014 Mar 3;10:535-43. doi: 10.3762/bjoc.10.49. eCollection 2014.

16.

The myxobacterial metabolite ratjadone A inhibits HIV infection by blocking the Rev/CRM1-mediated nuclear export pathway.

Fleta-Soriano E, Martinez JP, Hinkelmann B, Gerth K, Washausen P, Diez J, Frank R, Sasse F, Meyerhans A.

Microb Cell Fact. 2014 Jan 29;13:17. doi: 10.1186/1475-2859-13-17.

17.

Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology.

Martínez JP, Pérez-Vilaró G, Muthukumar Y, Scheller N, Hirsch T, Diestel R, Steinmetz H, Jansen R, Frank R, Sasse F, Meyerhans A, Díez J.

RNA Biol. 2013 Nov;10(11):1661-9. doi: 10.4161/rna.26851.

18.

Synthesis and biological evaluation of paleo-soraphens.

Lu HH, Raja A, Franke R, Landsberg D, Sasse F, Kalesse M.

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13549-52. doi: 10.1002/anie.201305331. Epub 2013 Nov 7.

PMID:
24346938
19.

Total synthesis and biological evaluation of jerantinine E.

Frei R, Staedler D, Raja A, Franke R, Sasse F, Gerber-Lemaire S, Waser J.

Angew Chem Int Ed Engl. 2013 Dec 9;52(50):13373-6. doi: 10.1002/anie.201305533. Epub 2013 Oct 14. No abstract available.

PMID:
24127420
20.

Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay.

Martinez JP, Hinkelmann B, Fleta-Soriano E, Steinmetz H, Jansen R, Diez J, Frank R, Sasse F, Meyerhans A.

Microb Cell Fact. 2013 Sep 24;12:85. doi: 10.1186/1475-2859-12-85.

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