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Results: 1 to 20 of 66

1.

Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.

Thomas JB, Giddings AM, Olepu S, Wiethe RW, Harris DL, Narayanan S, Warner KR, Sarret P, Longpre JM, Runyon SP, Gilmour BP.

Bioorg Med Chem Lett. 2014 Nov 24. pii: S0960-894X(14)01231-1. doi: 10.1016/j.bmcl.2014.11.047. [Epub ahead of print]

PMID:
25499438
[PubMed - as supplied by publisher]
2.

Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Sep 11;57(17):7472-7. doi: 10.1021/jm500857r. Epub 2014 Aug 26.

PMID:
25157640
[PubMed - indexed for MEDLINE]
3.

Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.

Thomas JB, Giddings AM, Wiethe RW, Olepu S, Warner KR, Sarret P, Gendron L, Longpre JM, Zhang Y, Runyon SP, Gilmour BP.

J Med Chem. 2014 Jun 26;57(12):5318-32. doi: 10.1021/jm5003843. Epub 2014 Jun 5.

PMID:
24856674
[PubMed - indexed for MEDLINE]
4.

Preventive effect of α-lipoic acid on prepulse inhibition deficits in a juvenile two-hit model of schizophrenia.

Deslauriers J, Racine W, Sarret P, Grignon S.

Neuroscience. 2014 Jul 11;272:261-70. doi: 10.1016/j.neuroscience.2014.04.061. Epub 2014 May 9.

PMID:
24813434
[PubMed - in process]
5.

Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid.

Murza A, Belleville K, Longpré JM, Sarret P, Marsault E.

Biopolymers. 2014 Apr;101(4):297-303. doi: 10.1002/bip.22498.

PMID:
24728860
[PubMed - in process]
6.

Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation.

Belkouch M, Dansereau MA, Tétreault P, Biet M, Beaudet N, Dumaine R, Chraibi A, Mélik-Parsadaniantz S, Sarret P.

J Neuroinflammation. 2014 Mar 7;11:45. doi: 10.1186/1742-2094-11-45.

PMID:
24606981
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.

Demeule M, Beaudet N, Régina A, Besserer-Offroy É, Murza A, Tétreault P, Belleville K, Ché C, Larocque A, Thiot C, Béliveau R, Longpré JM, Marsault É, Leduc R, Lachowicz JE, Gonias SL, Castaigne JP, Sarret P.

J Clin Invest. 2014 Mar 3;124(3):1199-213. doi: 10.1172/JCI70647. Epub 2014 Feb 17.

PMID:
24531547
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Improving the selection of true incident cases of low back pain by screening retrospective administrative data.

Beaudet N, Courteau J, Sarret P, Vanasse A.

Eur J Pain. 2014 Aug;18(7):923-31. doi: 10.1002/j.1532-2149.2013.00437.x. Epub 2013 Dec 16.

PMID:
24343901
[PubMed - in process]
9.

Implication of the ERK/MAPK pathway in antipsychotics-induced dopamine D2 receptor upregulation and in the preventive effects of (±)-α-lipoic acid in SH-SY5Y neuroblastoma cells.

Deslauriers J, Desmarais C, Sarret P, Grignon S.

J Mol Neurosci. 2014 Mar;52(3):378-83. doi: 10.1007/s12031-013-0158-6. Epub 2013 Nov 8.

PMID:
24203573
[PubMed - indexed for MEDLINE]
10.

Spinal NTS2 receptor activation reverses signs of neuropathic pain.

Tétreault P, Beaudet N, Perron A, Belleville K, René A, Cavelier F, Martinez J, Stroh T, Jacobi AM, Rose SD, Behlke MA, Sarret P.

FASEB J. 2013 Sep;27(9):3741-52. doi: 10.1096/fj.12-225540. Epub 2013 Jun 11.

PMID:
23756650
[PubMed - indexed for MEDLINE]
Free Article
11.

Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers.

Deslauriers J, Larouche A, Sarret P, Grignon S.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:156-64. doi: 10.1016/j.pnpbp.2013.05.006. Epub 2013 May 19.

PMID:
23697796
[PubMed - indexed for MEDLINE]
12.

Prevalence of claims-based recurrent low back pain in a Canadian population: a secondary analysis of an administrative database.

Beaudet N, Courteau J, Sarret P, Vanasse A.

BMC Musculoskelet Disord. 2013 Apr 29;14:151. doi: 10.1186/1471-2474-14-151.

PMID:
23628144
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mammary cancer bone metastasis follow-up using multimodal small-animal MR and PET imaging.

Doré-Savard L, Barrière DA, Midavaine É, Bélanger D, Beaudet N, Tremblay L, Beaudoin JF, Turcotte EE, Lecomte R, Lepage M, Sarret P.

J Nucl Med. 2013 Jun;54(6):944-52. doi: 10.2967/jnumed.112.114215. Epub 2013 Apr 17.

PMID:
23596003
[PubMed - indexed for MEDLINE]
Free Article
14.

Postnatal administration of IL-1Ra exerts neuroprotective effects following perinatal inflammation and/or hypoxic-ischemic injuries.

Girard S, Sébire H, Brochu ME, Briota S, Sarret P, Sébire G.

Brain Behav Immun. 2012 Nov;26(8):1331-9. doi: 10.1016/j.bbi.2012.09.001. Epub 2012 Sep 13.

PMID:
22982341
[PubMed - indexed for MEDLINE]
15.

α-Lipoic acid interaction with dopamine D2 receptor-dependent activation of the Akt/GSK-3β signaling pathway induced by antipsychotics: potential relevance for the treatment of schizophrenia.

Deslauriers J, Desmarais C, Sarret P, Grignon S.

J Mol Neurosci. 2013 May;50(1):134-45. doi: 10.1007/s12031-012-9884-4. Epub 2012 Sep 14.

PMID:
22975849
[PubMed - indexed for MEDLINE]
16.

A micro-imaging study linking bone cancer pain with tumor growth and bone resorption in a rat model.

Doré-Savard L, Beaudet N, Tremblay L, Xiao Y, Lepage M, Sarret P.

Clin Exp Metastasis. 2013 Feb;30(2):225-36. doi: 10.1007/s10585-012-9530-0. Epub 2012 Sep 6.

PMID:
22956259
[PubMed - indexed for MEDLINE]
17.

Intrathecal administration of NTS1 agonists reverses nociceptive behaviors in a rat model of neuropathic pain.

Guillemette A, Dansereau MA, Beaudet N, Richelson E, Sarret P.

Eur J Pain. 2012 Apr;16(4):473-84. doi: 10.1016/j.ejpain.2011.07.008.

PMID:
22396077
[PubMed - indexed for MEDLINE]
18.

Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain.

Parent AJ, Beaudet N, Beaudry H, Bergeron J, Bérubé P, Drolet G, Sarret P, Gendron L.

Behav Brain Res. 2012 Apr 1;229(1):160-7. doi: 10.1016/j.bbr.2012.01.001. Epub 2012 Jan 8.

PMID:
22245257
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The chemokine CCL2 increases Nav1.8 sodium channel activity in primary sensory neurons through a Gβγ-dependent mechanism.

Belkouch M, Dansereau MA, Réaux-Le Goazigo A, Van Steenwinckel J, Beaudet N, Chraibi A, Melik-Parsadaniantz S, Sarret P.

J Neurosci. 2011 Dec 14;31(50):18381-90. doi: 10.1523/JNEUROSCI.3386-11.2011.

PMID:
22171040
[PubMed - indexed for MEDLINE]
Free Article
20.

Elucidation of the structure-activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability.

Murza A, Parent A, Besserer-Offroy E, Tremblay H, Karadereye F, Beaudet N, Leduc R, Sarret P, Marsault É.

ChemMedChem. 2012 Feb 6;7(2):318-25. doi: 10.1002/cmdc.201100492. Epub 2011 Dec 13.

PMID:
22170700
[PubMed - indexed for MEDLINE]

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