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Items: 17


Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration.

Kircher P, Hermanns C, Nossek M, Drexler MK, Grosse R, Fischer M, Sarikas A, Penkava J, Lewis T, Prywes R, Gudermann T, Muehlich S.

Sci Signal. 2015 Nov 10;8(402):ra112. doi: 10.1126/scisignal.aad2959.


Use of learning media by undergraduate medical students in pharmacology: a prospective cohort study.

Gutmann J, Kühbeck F, Berberat PO, Fischer MR, Engelhardt S, Sarikas A.

PLoS One. 2015 Apr 7;10(4):e0122624. doi: 10.1371/journal.pone.0122624. eCollection 2015.


Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology.

Kräenbring J, Monzon Penza T, Gutmann J, Muehlich S, Zolk O, Wojnowski L, Maas R, Engelhardt S, Sarikas A.

PLoS One. 2014 Sep 24;9(9):e106930. doi: 10.1371/journal.pone.0106930. eCollection 2014.

4. novel web-based audience response system for higher education. A pilot study to evaluate user acceptance.

Kühbeck F, Engelhardt S, Sarikas A.

GMS Z Med Ausbild. 2014 Feb 17;31(1):Doc5. doi: 10.3205/zma000897. eCollection 2014.


Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen.

Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3371-6. doi: 10.1073/pnas.1401556111. Epub 2014 Feb 18.


Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.

Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Muehlich S, Pfeiffer AF, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A.

Cell Signal. 2014 Feb;26(2):233-9. doi: 10.1016/j.cellsig.2013.11.005. Epub 2013 Nov 9.


Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.

Hampl V, Martin C, Aigner A, Hoebel S, Singer S, Frank N, Sarikas A, Ebert O, Prywes R, Gudermann T, Muehlich S.

EMBO Mol Med. 2013 Sep;5(9):1367-82. doi: 10.1002/emmm.201202406. Epub 2013 Jul 29.


Internet discussion forums as part of a student-centred teaching concept of pharmacology.

Sucha M, Engelhardt S, Sarikas A.

GMS Z Med Ausbild. 2013;30(1):Doc2. doi: 10.3205/zma000845. Epub 2013 Feb 21.

9. - a student-centered e-learning project of clinical pharmacology.

Zollner B, Sucha M, Berg C, Muß N, Amann P, Amann-Neher B, Oestreicher D, Engelhardt S, Sarikas A.

Med Teach. 2013;35(3):251-3. doi: 10.3109/0142159X.2013.759642. Epub 2013 Jan 22.


Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination.

Xu X, Keshwani M, Meyer K, Sarikas A, Taylor S, Pan ZQ.

J Biol Chem. 2012 Nov 23;287(48):40758-66. doi: 10.1074/jbc.M112.405209. Epub 2012 Oct 8.


The cullin protein family.

Sarikas A, Hartmann T, Pan ZQ.

Genome Biol. 2011;12(4):220. doi: 10.1186/gb-2011-12-4-220. Epub 2011 Apr 28. Review.


The cullin7 E3 ubiquitin ligase: a novel player in growth control.

Sarikas A, Xu X, Field LJ, Pan ZQ.

Cell Cycle. 2008 Oct;7(20):3154-61. Epub 2008 Oct 4. Review.


Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail.

Yamoah K, Oashi T, Sarikas A, Gazdoiu S, Osman R, Pan ZQ.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12230-5. doi: 10.1073/pnas.0806155105. Epub 2008 Aug 22.


The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation.

Xu X, Sarikas A, Dias-Santagata DC, Dolios G, Lafontant PJ, Tsai SC, Zhu W, Nakajima H, Nakajima HO, Field LJ, Wang R, Pan ZQ.

Mol Cell. 2008 May 23;30(4):403-14. doi: 10.1016/j.molcel.2008.03.009.


Proteomic expression analysis of cardiomyocytes subjected to proteasome inhibition.

Doll D, Sarikas A, Krajcik R, Zolk O.

Biochem Biophys Res Commun. 2007 Feb 9;353(2):436-42. Epub 2006 Dec 12.


The ubiquitin-proteasome system: focus on the heart.

Zolk O, Schenke C, Sarikas A.

Cardiovasc Res. 2006 Jun 1;70(3):410-21. Epub 2006 Feb 23. Review.


Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants.

Sarikas A, Carrier L, Schenke C, Doll D, Flavigny J, Lindenberg KS, Eschenhagen T, Zolk O.

Cardiovasc Res. 2005 Apr 1;66(1):33-44.

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