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Items: 1 to 20 of 100

1.

The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells During Carcinogenesis.

Riesco-Eizaguirre G, Wert-Lamas L, Perales-Patón J, Sastre-Perona A, Fernández LP, Santisteban P.

Cancer Res. 2015 Aug 17. pii: canres.3547.2014. [Epub ahead of print]

PMID:
26282166
2.

Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type I diabetes rats.

Romaní-Pérez M, Outeiriño-Iglesias V, Moya CM, Santisteban P, González-Matías LC, Vigo E, Mallo F.

Endocrinology. 2015 Jul 21:en20141685. [Epub ahead of print]

PMID:
26196539
3.

DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

Cardoso-Weide LC, Cardoso-Penha RC, Costa MW, Ferreira AC, Carvalho DP, Santisteban PS.

Eur Thyroid J. 2015 Mar;4(1):6-13. doi: 10.1159/000379749. Epub 2015 Mar 7.

PMID:
25960956
4.

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.

Mancikova V, Cruz R, Inglada-Pérez L, Fernández-Rozadilla C, Landa I, Cameselle-Teijeiro J, Celeiro C, Pastor S, Velázquez A, Marcos R, Andía V, Álvarez-Escolá C, Meoro A, Schiavi F, Opocher G, Quintela I, Ansede-Bermejo J, Ruiz-Ponte C, Santisteban P, Robledo M, Carracedo A.

Int J Cancer. 2015 Oct 15;137(8):1870-8. doi: 10.1002/ijc.29557. Epub 2015 Apr 22.

PMID:
25855579
5.

MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors.

Mancikova V, Castelblanco E, Pineiro-Yanez E, Perales-Paton J, de Cubas AA, Inglada-Perez L, Matias-Guiu X, Capel I, Bella M, Lerma E, Riesco-Eizaguirre G, Santisteban P, Maravall F, Mauricio D, Al-Shahrour F, Robledo M.

Mod Pathol. 2015 Jun;28(6):748-57. doi: 10.1038/modpathol.2015.44. Epub 2015 Feb 27.

PMID:
25720323
6.

Thyroid transcription factors in development, differentiation and disease.

Fernández LP, López-Márquez A, Santisteban P.

Nat Rev Endocrinol. 2015 Jan;11(1):29-42. doi: 10.1038/nrendo.2014.186. Epub 2014 Oct 28.

PMID:
25350068
7.

Association between BRAF V600E mutation and recurrence of papillary thyroid cancer.

Xing M, Alzahrani AS, Carson KA, Shong YK, Kim TY, Viola D, Elisei R, Bendlová B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Clifton-Bligh R, Tallini G, Holt EH, Sýkorová V.

J Clin Oncol. 2015 Jan 1;33(1):42-50. doi: 10.1200/JCO.2014.56.8253. Epub 2014 Oct 20.

PMID:
25332244
8.

NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer.

Riesco-Eizaguirre G, Leoni SG, Mendiola M, Estevez-Cebrero MA, Gallego MI, Redondo A, Hardisson D, Santisteban P, De la Vieja A.

J Clin Endocrinol Metab. 2014 Jul;99(7):E1199-208. doi: 10.1210/jc.2013-4249. Epub 2014 Apr 7.

PMID:
24708099
9.

Wnt-independent role of β-catenin in thyroid cell proliferation and differentiation.

Sastre-Perona A, Santisteban P.

Mol Endocrinol. 2014 May;28(5):681-95. doi: 10.1210/me.2013-1377. Epub 2014 Mar 19.

PMID:
24645679
10.

An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility.

Landa I, Boullosa C, Inglada-Pérez L, Sastre-Perona A, Pastor S, Velázquez A, Mancikova V, Ruiz-Llorente S, Schiavi F, Marcos R, Malats N, Opocher G, Diaz-Uriarte R, Santisteban P, Valencia A, Robledo M.

PLoS One. 2013 Sep 23;8(9):e74765. doi: 10.1371/journal.pone.0074765. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/cd94c3eb-70f2-4dfa-85be-b3fc41e495c3.

11.

New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells.

Fernández LP, López-Márquez A, Martínez AM, Gómez-López G, Santisteban P.

PLoS One. 2013 May 13;8(5):e62849. doi: 10.1371/journal.pone.0062849. Print 2013.

12.

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

Rodríguez-Rodero S, Fernández AF, Fernández-Morera JL, Castro-Santos P, Bayon GF, Ferrero C, Urdinguio RG, Gonzalez-Marquez R, Suarez C, Fernández-Vega I, Fresno Forcelledo MF, Martínez-Camblor P, Mancikova V, Castelblanco E, Perez M, Marrón PI, Mendiola M, Hardisson D, Santisteban P, Riesco-Eizaguirre G, Matías-Guiu X, Carnero A, Robledo M, Delgado-Álvarez E, Menéndez-Torre E, Fraga MF.

J Clin Endocrinol Metab. 2013 Jul;98(7):2811-21. doi: 10.1210/jc.2012-3566. Epub 2013 May 10.

PMID:
23666970
13.

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.

Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Tufano RP, Pai SI, Zeiger MA, Westra WH, Clark DP, Clifton-Bligh R, Sidransky D, Ladenson PW, Sykorova V.

JAMA. 2013 Apr 10;309(14):1493-501. doi: 10.1001/jama.2013.3190.

14.

FOXO1 controls thyroid cell proliferation in response to TSH and IGF-I and is involved in thyroid tumorigenesis.

Zaballos MA, Santisteban P.

Mol Endocrinol. 2013 Jan;27(1):50-62. doi: 10.1210/me.2012-1032. Epub 2012 Nov 16.

PMID:
23160481
15.

Role of the wnt pathway in thyroid cancer.

Sastre-Perona A, Santisteban P.

Front Endocrinol (Lausanne). 2012 Feb 29;3:31. doi: 10.3389/fendo.2012.00031. eCollection 2012.

16.

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions.

Ruiz-Llorente S, Carrillo Santa de Pau E, Sastre-Perona A, Montero-Conde C, Gómez-López G, Fagin JA, Valencia A, Pisano DG, Santisteban P.

BMC Genomics. 2012 Apr 24;13:147. doi: 10.1186/1471-2164-13-147.

17.

DARPP-32 is required for MAPK/ERK signaling in thyroid cells.

Chocarro-Calvo A, Zaballos MA, Santisteban P, García-Jiménez C.

Mol Endocrinol. 2012 Mar;26(3):471-80. doi: 10.1210/me.2011-1309. Epub 2012 Feb 2.

PMID:
22301787
18.

Regulation of thyroid oxidative state by thioredoxin reductase has a crucial role in thyroid responses to iodide excess.

Leoni SG, Kimura ET, Santisteban P, De la Vieja A.

Mol Endocrinol. 2011 Nov;25(11):1924-35. doi: 10.1210/me.2011-0038. Epub 2011 Sep 8.

PMID:
21903721
19.

Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach.

Riesco-Eizaguirre G, De la Vieja A, Rodríguez I, Miranda S, Martín-Duque P, Vassaux G, Santisteban P.

J Clin Endocrinol Metab. 2011 Sep;96(9):E1435-43. doi: 10.1210/jc.2010-2373. Epub 2011 Jun 22.

PMID:
21697253
20.

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation.

Santisteban P, Recacha P, Metzger DE, Zaret KS.

Dev Dyn. 2010 Mar;239(3):980-6. doi: 10.1002/dvdy.22217.

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