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Results: 20

1.

Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro.

Sandholm J, Tuomela J, Kauppila JH, Harris KW, Graves D, Selander KS.

Oncol Lett. 2014 Jul;8(1):266-274. Epub 2014 Apr 25.

PMID:
24959259
[PubMed]
Free PMC Article
2.

Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer.

Tuomela J, Sandholm J, Kauppila JH, Lehenkari P, Harris KW, Selander KS.

Oncol Lett. 2013 Dec;6(6):1665-1672. Epub 2013 Oct 4.

PMID:
24273604
[PubMed]
Free PMC Article
3.

DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells.

Tuomela J, Sandholm J, Kaakinen M, Patel A, Kauppila JH, Ilvesaro J, Chen D, Harris KW, Graves D, Selander KS.

Breast Cancer Res Treat. 2013 Dec;142(3):477-87. doi: 10.1007/s10549-013-2762-0. Epub 2013 Nov 10.

PMID:
24212717
[PubMed - indexed for MEDLINE]
4.

Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer.

Tuomela J, Sandholm J, Karihtala P, Ilvesaro J, Vuopala KS, Kauppila JH, Kauppila S, Chen D, Pressey C, Härkönen P, Harris KW, Graves D, Auvinen PK, Soini Y, Jukkola-Vuorinen A, Selander KS.

Breast Cancer Res Treat. 2012 Sep;135(2):481-93. doi: 10.1007/s10549-012-2181-7. Epub 2012 Jul 31.

PMID:
22847512
[PubMed - indexed for MEDLINE]
5.

Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes.

Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M.

Glia. 2011 Nov;59(11):1643-57. doi: 10.1002/glia.21212. Epub 2011 Aug 8.

PMID:
21826742
[PubMed - indexed for MEDLINE]
6.

Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes.

Heinonen J, Taipaleenmäki H, Roering P, Takatalo M, Harkness L, Sandholm J, Uusitalo-Järvinen H, Kassem M, Kiviranta I, Laitala-Leinonen T, Säämänen AM.

Osteoarthritis Cartilage. 2011 Aug;19(8):1026-35. doi: 10.1016/j.joca.2011.04.016. Epub 2011 May 17.

PMID:
21624478
[PubMed - indexed for MEDLINE]
Free Article
7.

Estrogen receptor-α and sex steroid hormones regulate Toll-like receptor-9 expression and invasive function in human breast cancer cells.

Sandholm J, Kauppila JH, Pressey C, Tuomela J, Jukkola-Vuorinen A, Vaarala M, Johnson MR, Harris KW, Selander KS.

Breast Cancer Res Treat. 2012 Apr;132(2):411-9. doi: 10.1007/s10549-011-1590-3. Epub 2011 May 24.

PMID:
21607583
[PubMed - indexed for MEDLINE]
8.

Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.

Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Björkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nguyen L, Kallunki T, Courtney MJ, Coffey ET.

Nat Neurosci. 2011 Mar;14(3):305-13. doi: 10.1038/nn.2755. Epub 2011 Feb 6.

PMID:
21297631
[PubMed - indexed for MEDLINE]
9.

Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts.

Tuomela J, Grönroos TJ, Valta MP, Sandholm J, Schrey A, Seppänen J, Marjamäki P, Forsback S, Kinnunen I, Solin O, Minn H, Härkönen PL.

BMC Cancer. 2010 Oct 30;10:596. doi: 10.1186/1471-2407-10-596.

PMID:
21034500
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion.

Santio NM, Vahakoski RL, Rainio EM, Sandholm JA, Virtanen SS, Prudhomme M, Anizon F, Moreau P, Koskinen PJ.

Mol Cancer. 2010 Oct 19;9:279. doi: 10.1186/1476-4598-9-279.

PMID:
20958956
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells.

Virtanen SS, Sandholm J, Yegutkin G, Kalervo Väänänen H, Härkönen PL.

Cell Biol Int. 2010 Aug;34(8):815-26. doi: 10.1042/CBI20090288.

PMID:
20446922
[PubMed - indexed for MEDLINE]
12.

Pim-1 kinase expression predicts radiation response in squamocellular carcinoma of head and neck and is under the control of epidermal growth factor receptor.

Peltola K, Hollmen M, Maula SM, Rainio E, Ristamäki R, Luukkaa M, Sandholm J, Sundvall M, Elenius K, Koskinen PJ, Grenman R, Jalkanen S.

Neoplasia. 2009 Jul;11(7):629-36.

PMID:
19568408
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reconstruction of critical size calvarial bone defects in rabbits with glass-fiber-reinforced composite with bioactive glass granule coating.

Tuusa SM, Peltola MJ, Tirri T, Puska MA, Röyttä M, Aho H, Sandholm J, Lassila LV, Vallittu PK.

J Biomed Mater Res B Appl Biomater. 2008 Feb;84(2):510-9.

PMID:
17618510
[PubMed - indexed for MEDLINE]
14.

Intrinsic properties of so-called dormant probiotic bacteria, determined by flow cytometric viability assays.

Lahtinen SJ, Ouwehand AC, Reinikainen JP, Korpela JM, Sandholm J, Salminen SJ.

Appl Environ Microbiol. 2006 Jul;72(7):5132-4.

PMID:
16820522
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity.

Aho TL, Sandholm J, Peltola KJ, Ito Y, Koskinen PJ.

BMC Cell Biol. 2006 May 9;7:21.

PMID:
16684349
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.

Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ.

FEBS Lett. 2004 Jul 30;571(1-3):43-9.

PMID:
15280015
[PubMed - indexed for MEDLINE]
Free Article
17.

Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase.

Rainio EM, Sandholm J, Koskinen PJ.

J Immunol. 2002 Feb 15;168(4):1524-7.

PMID:
11823475
[PubMed - indexed for MEDLINE]
Free Article
18.

The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.

Lilly M, Sandholm J, Cooper JJ, Koskinen PJ, Kraft A.

Oncogene. 1999 Jul 8;18(27):4022-31.

PMID:
10435626
[PubMed - indexed for MEDLINE]
Free Article
19.

Four SINE-associated polymorphic bovine microsatellites (HEL23-HEL26).

Vilkki J, Sandholm J, Kostia S, Varvio SL.

Anim Genet. 1995 Jun;26(3):206. No abstract available.

PMID:
7793697
[PubMed - indexed for MEDLINE]
20.

Distribution of nitrapyrin [12-chloro-6-(trichloromethyl)-pyridine] and 2-chloro-6-(dichloromethyl)-pyridine in red beet treated with nitrapyrin.

Kallio H, Sandholm J.

J Sci Food Agric. 1982 May;33(5):451-5. No abstract available.

PMID:
7087403
[PubMed - indexed for MEDLINE]

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